PDB entry 6y2v

View 6y2v on RCSB PDB site
Description: Crystal structure of the double mutant L13R I16K of Low Molecular Weight Protein Tyrosine Phosphatase (LMW-PTP)
Class: hydrolase
Keywords: Engineered, HYDROLASE
Deposited on 2020-02-17, released 2020-07-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-22, with a file datestamp of 2020-07-17.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Low molecular weight phosphotyrosine protein phosphatase
    Species: Homo sapiens [TaxId:9606]
    Gene: Acp1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24666 (Start-157)
      • engineered mutation (13)
      • engineered mutation (16)
    Domains in SCOPe 2.08: d6y2va_
  • Heterogens: PGE, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6y2vA (A:)
    maeqatksvlfvcrgnkcrspiaeavfrklvtdqnisenwvidsgavsdwnvgrspdpra
    vsclrnhgihtahkarqitkedfatfdyilcmdesnlrdlnrksnqvktckakiellgsy
    dpqkqliiedpyygndsdfetvyqqcvrccraflekah
    

    Sequence, based on observed residues (ATOM records): (download)
    >6y2vA (A:)
    tksvlfvcrgnkcrspiaeavfrklvtdqnisenwvidsgavsdwnvgrspdpravsclr
    nhgihtahkarqitkedfatfdyilcmdesnlrdlnrksnqvktckakiellgsydpqkq
    liiedpyygndsdfetvyqqcvrccraflekah