PDB entry 6y17

View 6y17 on RCSB PDB site
Description: Crystal structure of an NCoR1BBD2-BCL6BTB chimera in complex with nebulinSH3-NCoR1BBD1
Class: transcription
Keywords: BCL6, NCoR1., TRANSCRIPTION
Deposited on 2020-02-11, released 2020-12-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-03-24, with a file datestamp of 2021-03-19.
Experiment type: XRAY
Resolution: 1.56 Å
R-factor: N/A
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nuclear receptor corepressor 1,B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
    • Uniprot O75376 (Start-10)
      • linker (11-12)
    • Uniprot P41182 (13-End)
      • conflict (15)
      • conflict (74)
      • conflict (91)
    Domains in SCOPe 2.08: d6y17a_
  • Chain 'B':
    Compound: Nuclear receptor corepressor 1,B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
    • Uniprot O75376 (2-End)
      • expression tag (0-1)
    • Uniprot P41182 (13-End)
      • conflict (15)
      • conflict (74)
      • conflict (91)
    Domains in SCOPe 2.08: d6y17b1, d6y17b2
  • Chain 'C':
    Compound: Nebulin,Nuclear receptor corepressor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NCOR1, KIAA1047
    Database cross-references and differences (RAF-indexed):
    • Uniprot H0Y786 (Start-61)
      • linker (62-64)
    • Uniprot O75376 (65-81)
  • Chain 'D':
    Compound: Nebulin,Nuclear receptor corepressor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NCOR1, KIAA1047
    Database cross-references and differences (RAF-indexed):
    • Uniprot H0Y786 (2-61)
      • expression tag (0-1)
      • linker (62-64)
    • Uniprot O75376 (65-81)
  • Heterogens: NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6y17A (A:)
gpssdlylrpgggdsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlma
csglfysiftdqlkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamyl
qmehvvdtcrkfikase

    Sequence, based on observed residues (ATOM records): (download) 
    >6y17A (A:)
lrpgggdsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfys
iftdqlkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvd
tcrkfikas

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6y17B (B:)
gpssdlylrpgggdsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlma
csglfysiftdqlkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamyl
qmehvvdtcrkfikase

    Sequence, based on observed residues (ATOM records): (download) 
    >6y17B (B:)
gpssdlyldsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglf
ysiftdqlkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehv
vdtcrkfika

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.