PDB entry 6xyu

View 6xyu on RCSB PDB site
Description: Update of AChE from Drosophila Melanogaster complex with tacrine derivative 9-(3-iodobenzylamino)-1,2,3,4-tetrahydroacridine
Class: hydrolase
Keywords: acetylcholinesterase, insect, inhibitor, complex, HYDROLASE
Deposited on 2020-01-31, released 2020-03-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-05-05, with a file datestamp of 2021-04-30.
Experiment type: XRAY
Resolution: 2.51 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acetylcholinesterase
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Ace, CG17907
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6xyua_
  • Heterogens: IOD, I40, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6xyuA (A:)
vidrlvvqtssgpvrgrsvtvqgrevhvytgipyakppvedlrfrkpvpaepwhgvldat
glsatcvqeryeyfpgfsgeeiwnpntnvsedclyinvwapakarlrhgrganggehpng
kqadtdhlihngnpqnttnglpiliwiygggfmtgsatldiynadimaavgnvivasfqy
rvgafgflhlapempsefaeeapgnvglwdqalairwlkdnahafggnpewmtlfgesag
sssvnaqlmspvtrglvkrgmmqsgtmnapwshmtsekaveigkalindcncnasmlktn
pahvmscmrsvdaktisvqqwnsysgilsfpsaptidgaflpadpmtlmktadlkdydil
mgnvrdegtyfllydfidyfdkddatalprdkyleimnnifgkatqaereaiifqytswe
gnpgyqnqqqigravgdhfftcptneyaqalaergasvhyyyfthrtstslwgewmgvlh
gdeieyffgqplnnslqyrpverelgkrmlsaviefaktgnpaqdgeewpnfskedpvyy
ifstddkieklargplaarcsfwndylpkvrswagtcdgds

    Sequence, based on observed residues (ATOM records): (download) 
    >6xyuA (A:)
drlvvqtssgpvrgrsvtvqgrevhvytgipyakppvedlrfrkpvpaepwhgvldatgl
satcvqeryeyfpgfsgeeiwnpntnvsedclyinvwapattnglpiliwiygggfmtgs
atldiynadimaavgnvivasfqyrvgafgflhlapempsefaeeapgnvglwdqalair
wlkdnahafggnpewmtlfgesagsssvnaqlmspvtrglvkrgmmqsgtmnapwshmts
ekaveigkalindcncnasmlktnpahvmscmrsvdaktisvqqwnsysgilsfpsapti
dgaflpadpmtlmktadlkdydilmgnvrdegtyfllydfidyfdkddatalprdkylei
mnnifgkatqaereaiifqytswegnpgyqnqqqigravgdhfftcptneyaqalaerga
svhyyyfthrtstslwgewmgvlhgdeieyffgqplnnslqyrpverelgkrmlsavief
aktgnpaqdgeewpnfskedpvyyifstddkieklargplaarcsfwndylpkvrsw