PDB entry 6xxt

View 6xxt on RCSB PDB site
Description: The crystal structure of hCA II in complex with a 4-(4-aroylpiperazine-1-carbonyl)benzenesulfonamide derivative.
Class: lyase
Keywords: Protein-inhibitor adduct, LYASE
Deposited on 2020-01-28, released 2020-06-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-06-03, with a file datestamp of 2020-05-29.
Experiment type: XRAY
Resolution: 1.05 Å
R-factor: N/A
AEROSPACI score: 0.77 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'X':
    Compound: Carbonic anhydrase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00918 (2-End)
      • expression tag (1)
    Domains in SCOPe 2.08: d6xxtx1, d6xxtx2
  • Heterogens: O42, ZN, GOL, HOH

PDB Chain Sequences:

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >6xxtX (X:)
mgmshhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslr
ilnnghafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaael
hlvhwntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnf
dprgllpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepee
lmvdnwrpaqplknrqikasfk

    Sequence, based on observed residues (ATOM records): (download) 
    >6xxtX (X:)
gmshhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslri
lnnghafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelh
lvhwntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfd
prgllpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepeel
mvdnwrpaqplknrqikasf