PDB entry 6xwm

View 6xwm on RCSB PDB site
Description: Mechanism of substrate release in neurotransmitter:sodium symporters: the structure of LeuT in an inward-facing occluded conformation
Class: membrane protein
Keywords: Neurotransmitter:sodium symporters (NSS), MEMBRANE PROTEIN
Deposited on 2020-01-24, released 2020-05-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-11-25, with a file datestamp of 2020-11-20.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Na(+):neurotransmitter symporter (Snf family)
    Species: Aquifex aeolicus VF5 [TaxId:224324]
    Gene: snf, aq_2077
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6xwma_
  • Chain 'B':
    Compound: Na(+):neurotransmitter symporter (Snf family)
    Species: Aquifex aeolicus VF5 [TaxId:224324]
    Gene: snf, aq_2077
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6xwmb_
  • Heterogens: NA, PHE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6xwmA (A:)
mevkrehaatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmw
iewamgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfai
kflvglvpepppnatdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinv
silirgiskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkd
pgvwiaavgqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisip
aavaffgvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaim
qpmiafledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffgltel
iiffwifgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeeth
wtvwitrfyiiglflfltflvflaerrrnhesagtlvpr

    Sequence, based on observed residues (ATOM records): (download) 
    >6xwmA (A:)
glilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiewamgryggaq
ghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikflvglvpeppp
natdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsilirgiskgie
rfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgvwiaavgqif
ftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaavaffgvanav
aiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpmiafledelk
lsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiffwifgadka
weeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtvwitrfyiig
lflfltflvflaerrrnh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6xwmB (B:)
mevkrehaatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmw
iewamgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfai
kflvglvpepppnatdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinv
silirgiskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkd
pgvwiaavgqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisip
aavaffgvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaim
qpmiafledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffgltel
iiffwifgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeeth
wtvwitrfyiiglflfltflvflaerrrnhesagtlvpr

    Sequence, based on observed residues (ATOM records): (download) 
    >6xwmB (B:)
glilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiewamgryggaq
ghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikflvglvpeppp
natdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsilirgiskgie
rfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgvwiaavgqif
ftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaavaffgvanav
aiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpmiafledelk
lsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiffwifgadka
weeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtvwitrfyiig
lflfltflvflaerr