PDB entry 6xv6

View 6xv6 on RCSB PDB site
Description: human sirt6 3-318 in complex with adp-ribose
Deposited on 2020-01-21, released 2020-10-28
The last revision was dated 2021-05-05, with a file datestamp of 2021-04-30.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: nad-dependent protein deacetylase sirtuin-6
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT6, SIR2L6
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: nad-dependent protein deacetylase sirtuin-6
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT6, SIR2L6
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: nad-dependent protein deacetylase sirtuin-6
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT6, SIR2L6
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: nad-dependent protein deacetylase sirtuin-6
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT6, SIR2L6
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: nad-dependent protein deacetylase sirtuin-6
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT6, SIR2L6
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: nad-dependent protein deacetylase sirtuin-6
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT6, SIR2L6
    Database cross-references and differences (RAF-indexed):
  • Heterogens: AR6, ZN, NCA, GOL, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6xv6A (A:)
vnyaaglspyadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgip
dfrgphgvwtmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrs
gfprdklaelhgnmfveecakcktqyvrdtvvgtmglkatgrlctvakarglracrgelr
dtildwedslpdrdlaladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlq
ptkhdrhadlrihgyvdevmtrlmkhlgleipawdgprvleralpplprpptpklepkee
sptringsipagpkqe

    Sequence, based on observed residues (ATOM records):
    >6xv6A (A:)
nyaaglspyadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgipd
frgphgvwtmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrsg
fprdklaelhgnmfveecakcktqyvrdtvvgtmglkatgrlctvacrgelrdtildwed
slpdrdlaladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlqptkhdrha
dlrihgyvdevmtrlmkhlgleipawdgprvleralpplprpptpkle

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6xv6B (B:)
vnyaaglspyadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgip
dfrgphgvwtmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrs
gfprdklaelhgnmfveecakcktqyvrdtvvgtmglkatgrlctvakarglracrgelr
dtildwedslpdrdlaladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlq
ptkhdrhadlrihgyvdevmtrlmkhlgleipawdgprvleralpplprpptpklepkee
sptringsipagpkqe

    Sequence, based on observed residues (ATOM records):
    >6xv6B (B:)
dkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgipdfrgphgvwtm
eerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrsgfprdklaelh
gnmfveecakcktqyvrdtvvgtmglkatgrlctvaacrgelrdtildwedslpdrdlal
adeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlqptkhdrhadlrihgyvd
evmtrlmkhlgleipawdgprvleralpplprpptpkle

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6xv6C (C:)
vnyaaglspyadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgip
dfrgphgvwtmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrs
gfprdklaelhgnmfveecakcktqyvrdtvvgtmglkatgrlctvakarglracrgelr
dtildwedslpdrdlaladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlq
ptkhdrhadlrihgyvdevmtrlmkhlgleipawdgprvleralpplprpptpklepkee
sptringsipagpkqe

    Sequence, based on observed residues (ATOM records):
    >6xv6C (C:)
vnaglspyadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgipdf
rgphgvwtmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrsgf
prdklaelhgnmfveecakcktqyvrdtvvgtmglkatgrlctvaacrgelrdtildwed
slpdrdlaladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlqptkhdrha
dlrihgyvdevmtrlmkhlgleipawdgprvleralpplprpptpkl

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6xv6D (D:)
vnyaaglspyadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgip
dfrgphgvwtmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrs
gfprdklaelhgnmfveecakcktqyvrdtvvgtmglkatgrlctvakarglracrgelr
dtildwedslpdrdlaladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlq
ptkhdrhadlrihgyvdevmtrlmkhlgleipawdgprvleralpplprpptpklepkee
sptringsipagpkqe

    Sequence, based on observed residues (ATOM records):
    >6xv6D (D:)
yadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgipdfrgphgvw
tmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrsgfprdklae
lhgnmfveecakcktqyvrdtvvgtmglkatgrlctvacrgelrdtildwedslpdrdla
ladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlqptkhdrhadlrihgyv
devmtrlmkhlgleipawdgprvleralpplprpptpkle

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6xv6E (E:)
vnyaaglspyadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgip
dfrgphgvwtmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrs
gfprdklaelhgnmfveecakcktqyvrdtvvgtmglkatgrlctvakarglracrgelr
dtildwedslpdrdlaladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlq
ptkhdrhadlrihgyvdevmtrlmkhlgleipawdgprvleralpplprpptpklepkee
sptringsipagpkqe

    Sequence, based on observed residues (ATOM records):
    >6xv6E (E:)
adkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgipdfrgphgvwt
meerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrsgfprdklael
hgnmfveecakcktqyvrdtvvgtmglkatgrlctvacrgelrdtildwedslpdrdlal
adeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlqptkhdrhadlrihgyvd
evmtrlmkhlgleipawdgprvleralpplprpptpkle

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6xv6F (F:)
vnyaaglspyadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgip
dfrgphgvwtmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrs
gfprdklaelhgnmfveecakcktqyvrdtvvgtmglkatgrlctvakarglracrgelr
dtildwedslpdrdlaladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlq
ptkhdrhadlrihgyvdevmtrlmkhlgleipawdgprvleralpplprpptpklepkee
sptringsipagpkqe

    Sequence, based on observed residues (ATOM records):
    >6xv6F (F:)
vnyaaglspyadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgip
dfrgphgvwtmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrs
gfprdklaelhgnmfveecakcktqyvrdtvvgtmglkatgrlctvacrgelrdtildwe
dslpdrdlaladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlqptkhdrh
adlrihgyvdevmtrlmkhlgleipawdgprvleralpplprpptpkle