PDB entry 6xug

View 6xug on RCSB PDB site
Description: human ecto-5'-nucleotidase (cd73) in complex with a2410 (compound 53 in publication) in the closed form in crystal form iv
Deposited on 2020-01-19, released 2020-04-22
The last revision was dated 2020-09-23, with a file datestamp of 2020-09-18.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 5'-nucleotidase
    Species: Homo sapiens [TaxId:9606]
    Gene: NT5E, NT5, NTE
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21589 (0-522)
      • conflict (26)
      • conflict (284)
      • conflict (306)
      • conflict (376)
  • Chain 'B':
    Compound: 5'-nucleotidase
    Species: Homo sapiens [TaxId:9606]
    Gene: NT5E, NT5, NTE
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21589 (0-522)
      • conflict (26)
      • conflict (284)
      • conflict (306)
      • conflict (376)
  • Heterogens: O1Q, ZN, CA, PO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6xugA (A:)
weltilhtndvhsrleqtsedsskcvdasrcmggvarlftkvqqirraepnvllldagdq
yqgtiwftvykgaevahfmnalrydamalgnhefdngvegliepllkeakfpilsanika
kgplasqisglylpykvlpvgdevvgivgytsketpflsnpgtnlvfedeitalqpevdk
lktlnvnkiialghsgfemdkliaqkvrgvdvvvgghsntflytgnppskevpagkypfi
vtsddgrkvpvvqayafgkylgylkiefdergnvisshgnpilldssipedpsikadink
wriklddystqelgktivyldgssqscrfrecnmgnlicdaminnnlrhtdemfwnhvsm
cilngggirspiderndgtitwenlaavlpfggtfdlvqlkgstlkkafehsvhrygqst
geflqvggihvvydlsrkpgdrvvkldvlctkcrvpsydplkmdevykvilpnflanggd
gfqmikdellrhdsgdqdinvvstyiskmkviypavegrikfsggggagggghhhhhh

    Sequence, based on observed residues (ATOM records):
    >6xugA (A:)
weltilhtndvhsrleqtsedsskcvdasrcmggvarlftkvqqirraepnvllldagdq
yqgtiwftvykgaevahfmnalrydamalgnhefdngvegliepllkeakfpilsanika
kgplasqisglylpykvlpvgdevvgivgytsketpflsnpgtnlvfedeitalqpevdk
lktlnvnkiialghsgfemdkliaqkvrgvdvvvgghsntflytgnppskevpagkypfi
vtsddgrkvpvvqayafgkylgylkiefdergnvisshgnpilldssipedpsikadink
wriklddystqelgktivyldgssqscrfrecnmgnlicdaminnnlrhvsmcilngggi
rspiderndgtitwenlaavlpfggtfdlvqlkgstlkkafehsvhrygqstgeflqvgg
ihvvydlsrkpgdrvvkldvlctkcrvpsydplkmdevykvilpnflanggdgfqmikde
llrhdsgdqdinvvstyiskmkviypavegrikfs

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6xugB (B:)
weltilhtndvhsrleqtsedsskcvdasrcmggvarlftkvqqirraepnvllldagdq
yqgtiwftvykgaevahfmnalrydamalgnhefdngvegliepllkeakfpilsanika
kgplasqisglylpykvlpvgdevvgivgytsketpflsnpgtnlvfedeitalqpevdk
lktlnvnkiialghsgfemdkliaqkvrgvdvvvgghsntflytgnppskevpagkypfi
vtsddgrkvpvvqayafgkylgylkiefdergnvisshgnpilldssipedpsikadink
wriklddystqelgktivyldgssqscrfrecnmgnlicdaminnnlrhtdemfwnhvsm
cilngggirspiderndgtitwenlaavlpfggtfdlvqlkgstlkkafehsvhrygqst
geflqvggihvvydlsrkpgdrvvkldvlctkcrvpsydplkmdevykvilpnflanggd
gfqmikdellrhdsgdqdinvvstyiskmkviypavegrikfsggggagggghhhhhh

    Sequence, based on observed residues (ATOM records):
    >6xugB (B:)
weltilhtndvhsrleqtsedsskcvdasrcmggvarlftkvqqirraepnvllldagdq
yqgtiwftvykgaevahfmnalrydamalgnhefdngvegliepllkeakfpilsanika
kgplasqisglylpykvlpvgdevvgivgytsketpflsnpgtnlvfedeitalqpevdk
lktlnvnkiialghsgfemdkliaqkvrgvdvvvgghsntflytgnppskevpagkypfi
vtsddgrkvpvvqayafgkylgylkiefdergnvisshgnpilldssipedpsikadink
wriklddystqelgktivyldgssqscrfrecnmgnlicdaminnnlrvsmcilngggir
spiderndgtitwenlaavlpfggtfdlvqlkgstlkkafehsvhrygqstgeflqvggi
hvvydlsrkpgdrvvkldvlctkcrvpsydplkmdevykvilpnflanggdgfqmikdel
lrhdsgdqdinvvstyiskmkviypavegrikfs