PDB entry 6xrt

View 6xrt on RCSB PDB site
Description: cryo-em structure of shiv-elicited rha1.v2.01 in complex with hiv-1 env bg505 ds-sosip.664
Deposited on 2020-07-13, released 2020-10-07
The last revision was dated 2021-01-20, with a file datestamp of 2021-01-15.
Experiment type: EM
Resolution: 3.9 Å
R-factor: N/A
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp41
    Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
    Gene: ENV
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2N0S6 (Start-152)
      • engineered mutation (93)
  • Chain 'B':
    Compound: HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp41
    Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
    Gene: ENV
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2N0S6 (Start-152)
      • engineered mutation (93)
  • Chain 'C':
    Compound: HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp41
    Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
    Gene: ENV
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2N0S6 (Start-152)
      • engineered mutation (93)
  • Chain 'E':
    Compound: envelope glycoprotein gp160
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: ENV
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2N0S6
      • conflict (170)
      • conflict (300)
      • conflict (400)
      • conflict (468)
  • Chain 'F':
    Compound: envelope glycoprotein gp160
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: ENV
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2N0S6
      • conflict (170)
      • conflict (300)
      • conflict (400)
      • conflict (468)
  • Chain 'G':
    Compound: envelope glycoprotein gp160
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: ENV
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2N0S6
      • conflict (170)
      • conflict (300)
      • conflict (400)
      • conflict (468)
  • Chain 'H':
    Compound: VRC01.23 Heavy Chain
    Species: MACACA MULATTA [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 6XRT (0-132)
  • Chain 'L':
    Compound: VRC01.23 Light Chain
    Species: MACACA MULATTA [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 6XRT (0-104)
  • Heterogens: BMA, MAN, NAG, TYS

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6xrtA (A:)
avgigavflgflgaagstmgaasmtltvqarnllsgivqqqsnllrapeaqqhllkltvw
gikqlqarvlaverylrdqqllgiwgcsgklicctnvpwnsswsnrnlseiwdnmtwlqw
dkeisnytqiiyglleesqnqqekneqdllald

    Sequence, based on observed residues (ATOM records):
    >6xrtA (A:)
flgflgaagstmgaasmtltvqarnlltvwgikqlqarvlaverylrdqqllgiwgcsgk
licctnvpwnsswsnrnlseiwdmtwlqwdkeisnytqiiyglleesqnqqekneqdlla
ld

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6xrtB (B:)
avgigavflgflgaagstmgaasmtltvqarnllsgivqqqsnllrapeaqqhllkltvw
gikqlqarvlaverylrdqqllgiwgcsgklicctnvpwnsswsnrnlseiwdnmtwlqw
dkeisnytqiiyglleesqnqqekneqdllald

    Sequence, based on observed residues (ATOM records):
    >6xrtB (B:)
lgflgaagstmgaasmtltvqarnllsltvwgikqlqarvlaverylrdqqllgiwgcsg
klicctnvpwnsswsnrnlseiwdnmtwlqwdkeisnytqiiyglleesqnqqekneqdl
lald

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6xrtC (C:)
avgigavflgflgaagstmgaasmtltvqarnllsgivqqqsnllrapeaqqhllkltvw
gikqlqarvlaverylrdqqllgiwgcsgklicctnvpwnsswsnrnlseiwdnmtwlqw
dkeisnytqiiyglleesqnqqekneqdllald

    Sequence, based on observed residues (ATOM records):
    >6xrtC (C:)
vflgflgaagstmgaasmtltvqarnllsltvwgikqlqarvlaverylrdqqllgiwgc
sgklicctnvpwnsswsnrnlseiwdnmtwlqwdkeisnytqiiyglleesqnqqekneq
dllald

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6xrtE (E:)
aenlwvtvyygvpvwkdaettlfcasdakayetekhnvwathacvptdpnpqeihlenvt
eefnmwknnmveqmhtdiislwdqslkpcvkltplcvtlqctnvtnnitddmrgelkncs
fnmttelrdkkqkvyslfyrldvvqinenqgnrsnnsnkeyrlincntsactqacpkvsf
epipihycapagfailkckdkkfngtgpcpsvstvqcthgikpvvstqlllngslaeeev
mirsenitnnaknilvqfntpvqinctrpnnntrksirigpgqafyatgdiigdirqahc
nvskatwnetlgkvvkqlrkhfgnntiirfanssggdlevtthsfncggeffycntsglf
nstwisntsvqgsnstgsndsitlpcrikqiinmwqrigqcmyappiqgvircvsnitgl
iltrdggstnsttetfrpgggdmrdnwrselykykvvkieplgvaptrckrrvvgr

    Sequence, based on observed residues (ATOM records):
    >6xrtE (E:)
enlwvtvyygvpvwkdaettlfcasdakhnvwathacvptdpnpqeihlenvteefnmwk
nnmveqmhtdiislwdqslkpcvkltplcvtlqctnvtnnitddmrgelkncsfnmttel
rdkkqkvyslfyrldvvqinnkeyrlincntsactqacpkvsfepipihycapagfailk
ckdkkfngtgpcpsvstvqcthgikpvvstqlllngslaeeevmirsenitnnaknilvq
fntpvqinctrpnnntrksirigpgqafyatgdiigdirqahcnvskatwnetlgkvvkq
lrkhfgnntiirfanssggdlevtthsfncggeffycntsglfnstwisnndsitlpcri
kqiinmwqrigqcmyappiqgvircvsnitgliltrdggstnsttetfrpgggdmrdnwr
selykykvvkieplgvaptrckrrvv

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6xrtF (F:)
aenlwvtvyygvpvwkdaettlfcasdakayetekhnvwathacvptdpnpqeihlenvt
eefnmwknnmveqmhtdiislwdqslkpcvkltplcvtlqctnvtnnitddmrgelkncs
fnmttelrdkkqkvyslfyrldvvqinenqgnrsnnsnkeyrlincntsactqacpkvsf
epipihycapagfailkckdkkfngtgpcpsvstvqcthgikpvvstqlllngslaeeev
mirsenitnnaknilvqfntpvqinctrpnnntrksirigpgqafyatgdiigdirqahc
nvskatwnetlgkvvkqlrkhfgnntiirfanssggdlevtthsfncggeffycntsglf
nstwisntsvqgsnstgsndsitlpcrikqiinmwqrigqcmyappiqgvircvsnitgl
iltrdggstnsttetfrpgggdmrdnwrselykykvvkieplgvaptrckrrvvgr

    Sequence, based on observed residues (ATOM records):
    >6xrtF (F:)
enlwvtvyygvpvwkdaettlfcasdahnvwathacvptdpnpqeihlenvteefnmwkn
nmveqmhtdiislwdqslkpcvkltplcvtlqctnvtnnitddmrgelkncsfnmttelr
dkkqkvyslfyrldvvqinnkeyrlincntsactqacpkvsfepipihycapagfailkc
kdkkfngtgpcpsvstvqcthgikpvvstqlllngslaeeevmirsenitnnaknilvqf
ntpvqinctrpnnntrksirigpgqafyatgdiigdirqahcnvskatwnetlgkvvkql
rkhfgnntiirfanssggdlevtthsfncggeffycntsglfnstwisnndsitlpcrik
qiinmwqrigqcmyappiqgvircvsnitgliltrdggstnsttetfrpgggdmrdnwrs
elykykvvkieplgvaptrckrrvv

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6xrtG (G:)
aenlwvtvyygvpvwkdaettlfcasdakayetekhnvwathacvptdpnpqeihlenvt
eefnmwknnmveqmhtdiislwdqslkpcvkltplcvtlqctnvtnnitddmrgelkncs
fnmttelrdkkqkvyslfyrldvvqinenqgnrsnnsnkeyrlincntsactqacpkvsf
epipihycapagfailkckdkkfngtgpcpsvstvqcthgikpvvstqlllngslaeeev
mirsenitnnaknilvqfntpvqinctrpnnntrksirigpgqafyatgdiigdirqahc
nvskatwnetlgkvvkqlrkhfgnntiirfanssggdlevtthsfncggeffycntsglf
nstwisntsvqgsnstgsndsitlpcrikqiinmwqrigqcmyappiqgvircvsnitgl
iltrdggstnsttetfrpgggdmrdnwrselykykvvkieplgvaptrckrrvvgr

    Sequence, based on observed residues (ATOM records):
    >6xrtG (G:)
enlwvtvyygvpvwkdaettlfcasdakkhnvwathacvptdpnpqeihlenvteefnmw
knnmveqmhtdiislwdqslkpcvkltplcvtlqctnvtnnitddmrgelkncsfnmtte
lrdkkqkvyslfyrldvvqinkeyrlincntsactqacpkvsfepipihycapagfailk
ckdkkfngtgpcpsvstvqcthgikpvvstqlllngslaeeevmirsenitnnaknilvq
fntpvqinctrpnnntrksirigpgqafyatgdiigdirqahcnvskatwnetlgkvvkq
lrkhfgnntiirfanssggdlevtthsfncggeffycntsglfnstwisntdsitlpcri
kqiinmwqrigqcmyappiqgvircvsnitgliltrdggstnsttetfrpgggdmrdnwr
selykykvvkieplgvaptrckrrvv

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records:
    >6xrtH (H:)
qvqlresgpglvkpsetlvltcavsgggdsfgfhywnwirqppgkglewighiggssgst
dfnpslksrvtismdssrnqfslrlksvtaadtavyfcarkgedfyeddygqyftagwff
dlwgpgtpiiiss

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records:
    >6xrtL (L:)
qfvltqppsvsgapgqtvtisctgrssnfgghyvqwyqqlpgtaprlvifendrrpsgvs
drfsgsqsgasasltitglqsedeadyycqcydssvlfgrgtrlt