PDB entry 6xqy

View 6xqy on RCSB PDB site
Description: Crystal structure of the catalytic domain of PBP2 S310A from Neisseria gonorrhoeae at pH 9.5
Class: hydrolase
Keywords: PBP2, beta-lactam, antibiotic target, TRANSFERASE, HYDROLASE
Deposited on 2020-07-10, released 2021-07-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-21, with a file datestamp of 2021-07-16.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Probable peptidoglycan D,D-transpeptidase PenA
    Species: NEISSERIA GONORRHOEAE [TaxId:485]
    Gene: penA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08149 (2-47)
      • expression tag (0-1)
      • linker (48-49)
    • Uniprot P08149 (50-326)
      • engineered mutation (62)
    Domains in SCOPe 2.08: d6xqya1, d6xqya2
  • Chain 'B':
    Compound: Probable peptidoglycan D,D-transpeptidase PenA
    Species: NEISSERIA GONORRHOEAE [TaxId:485]
    Gene: penA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08149 (2-47)
      • expression tag (0-1)
      • linker (48-49)
    • Uniprot P08149 (50-326)
      • engineered mutation (62)
    Domains in SCOPe 2.08: d6xqyb1, d6xqyb2
  • Heterogens: CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6xqyA (A:)
dmlsldqriqtlayeelnkaveyhqakagtvvvldartgeilalantpggrnravtdmie
pgaaikpfviakaldagktdlnerlntqpykigpspvrdthvypsldvrgimqkssnvgt
sklsarfgaeemydfyhelgigvrmhsgfpgetagllrnwrrwrpieqatmsfgyglqls
llqlaraytalthdgvllplsfekqavapqgkrifkestarevrnlmvsvtepggtgtag
avdgfdvgaktgtarkfvngryadnkhvatfigfapaknprvivavtideptahgyyggv
vagppfkkimggslnilgisptkplta

    Sequence, based on observed residues (ATOM records): (download) 
    >6xqyA (A:)
mlsldqriqtlayeelnkaveyhqakagtvvvldartgeilalantpggrnravtdmiep
gaaikpfviakaldagktdlnerlntqpykigpspvrdthvypsldvrgimqkssnvgts
klsarfgaeemydfyhelgigvrmhsgfpgetagllrnwrrwrpieqatmsfgyglqlsl
lqlaraytalthdgvllplsfekqavapqgkrifkestarevrnlmvsvtepggtgtaga
vdgfdvgaktgtarkkhvatfigfapaknprvivavtideptahgyyggvvagppfkkim
ggslnilgisptkplt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6xqyB (B:)
dmlsldqriqtlayeelnkaveyhqakagtvvvldartgeilalantpggrnravtdmie
pgaaikpfviakaldagktdlnerlntqpykigpspvrdthvypsldvrgimqkssnvgt
sklsarfgaeemydfyhelgigvrmhsgfpgetagllrnwrrwrpieqatmsfgyglqls
llqlaraytalthdgvllplsfekqavapqgkrifkestarevrnlmvsvtepggtgtag
avdgfdvgaktgtarkfvngryadnkhvatfigfapaknprvivavtideptahgyyggv
vagppfkkimggslnilgisptkplta

    Sequence, based on observed residues (ATOM records): (download) 
    >6xqyB (B:)
mlsldqriqtlayeelnkaveyhqakagtvvvldartgeilalantpggrnravtdmiep
gaaikpfviakaldagktdlnerlntqpykigpspvrdthvypsldvrgimqkssnvgts
klsarfgaeemydfyhelgigvrmhsgfpgetagllrnwrrwrpieqatmsfgyglqlsl
lqlaraytalthdgvllplsfekqavapqgkrifkestarevrnlmvsvtepggtgtaga
vdgfdvgaktgtarkfvngryadnkhvatfigfapaknprvivavtideptahgyyggvv
agppfkkimggslnilgisptkplta