PDB entry 6xpr

View 6xpr on RCSB PDB site
Description: human antibody d2 h1-1/h3-1 h3 in complex with the influenza hemagglutinin head domain of a/texas/50/2012(h3n2)
Deposited on 2020-07-08, released 2021-05-19
The last revision was dated 2021-07-28, with a file datestamp of 2021-07-23.
Experiment type: XRAY
Resolution: 4.09 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hemagglutinin
    Species: Influenza A virus (A/Texas/50/2012(H3N2)) [TaxId:1321009]
    Gene: HA, L998_47834gpHA
    Database cross-references and differences (RAF-indexed):
    • Uniprot R4L1D1 (0-282)
      • expression tag (283-290)
  • Chain 'B':
    Compound: antibody D2 H1-1/H3-1 H3 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6XPR (0-237)
  • Chain 'C':
    Compound: antibody D2 H1-1/H3-1 H3 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6XPR (0-213)
  • Chain 'D':
    Compound: Hemagglutinin
    Species: Influenza A virus (A/Texas/50/2012(H3N2)) [TaxId:1321009]
    Gene: HA, L998_47834gpHA
    Database cross-references and differences (RAF-indexed):
    • Uniprot R4L1D1 (0-282)
      • expression tag (283-290)
  • Chain 'E':
    Compound: antibody D2 H1-1/H3-1 H3 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6XPR (0-237)
  • Chain 'F':
    Compound: antibody D2 H1-1/H3-1 H3 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6XPR (0-213)
  • Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6xprA (A:)
tnatelvqnssigeicdsphqildgenctlidallgdpqcdgfqnkkwdlfverskaysn
cypydvpdyaslrslvassgtlefnnesfnwngvtqngtssacirrsnnsffsrlnwlth
lnfkypalnvtmpnneqfdklyiwgvhhpvtdkdqiflyaqpsgritvstkrsqqavipn
igfrprirnipsrisiywtivkpgdillinstgnliaprgyfkirsgkssimrsdapigk
cksecitpngsipndkpfqnvnritygacpryvkqstlklatggalevlfq

    Sequence, based on observed residues (ATOM records):
    >6xprA (A:)
telvqnssigeicdsphqildgenctlidallgdpqcdgfqnkkwdlfverskaysncyp
ydvpdyaslrslvassgtlefnnesfnwngvtqngtssacirrsnnsffsrlnwlthlnf
kypalnvtmpnneqfdklyiwgvhhpvtdkdqiflyaqpsgritvstkrsqqavipnigf
rprirnipsrisiywtivkpgdillinstgnliaprgyfkirsgkssimrsdapigkcks
ecitpngsipndkpfqnvnritygacpry

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6xprB (B:)
qvqlvqsggglvrpggslrlscaasgftfssawmtwvrqapgkglewvanikedgsekyy
vdsvkgrfsisrdnaknslylqisslraedtavyycarrfverlwgqskpydavdiwgqg
tmvtvsgastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtf
pavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkhhhhhh

    Sequence, based on observed residues (ATOM records):
    >6xprB (B:)
vqlvqsggglvrpggslrlscaasgftfssawmtwvrqapgkglewvanikedgsekyyv
dsvkgrfsisrdnaknslylqisslraedtavyycarrfverlwgqskpydavdiwgqgt
mvtvsgastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfp
avlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvep

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6xprC (C:)
diqmtqspsslsasvgdrvtitcrasqsisnylnwyqqkpgkapklliyvasnlqsgvps
rfsgsgsgtdfaltisslqpedfasyycqqsyspvttfgggtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >6xprC (C:)
diqmtqspsslsasvgdrvtitcrasqsisnylnwyqqkpgkapklliyvasnlqsgvps
rfsgsgsgtdfaltisslqpedfasyycqqsyspvttfgggtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnr

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6xprD (D:)
tnatelvqnssigeicdsphqildgenctlidallgdpqcdgfqnkkwdlfverskaysn
cypydvpdyaslrslvassgtlefnnesfnwngvtqngtssacirrsnnsffsrlnwlth
lnfkypalnvtmpnneqfdklyiwgvhhpvtdkdqiflyaqpsgritvstkrsqqavipn
igfrprirnipsrisiywtivkpgdillinstgnliaprgyfkirsgkssimrsdapigk
cksecitpngsipndkpfqnvnritygacpryvkqstlklatggalevlfq

    Sequence, based on observed residues (ATOM records):
    >6xprD (D:)
telvqnssigeicdsphqildgenctlidallgdpqcdgfqnkkwdlfverskaysncyp
ydvpdyaslrslvassgtlefnnesfnwngvtqngtssacirrsnnsffsrlnwlthlnf
kypalnvtmpnneqfdklyiwgvhhpvtdkdqiflyaqpsgritvstkrsqqavipnigf
rprirnipsrisiywtivkpgdillinstgnliaprgyfkirsgkssimrsdapigkcks
ecitpngsipndkpfqnvnritygacpry

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6xprE (E:)
qvqlvqsggglvrpggslrlscaasgftfssawmtwvrqapgkglewvanikedgsekyy
vdsvkgrfsisrdnaknslylqisslraedtavyycarrfverlwgqskpydavdiwgqg
tmvtvsgastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtf
pavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkhhhhhh

    Sequence, based on observed residues (ATOM records):
    >6xprE (E:)
vqlvqsggglvrpggslrlscaasgftfssawmtwvrqapgkglewvanikedgsekyyv
dsvkgrfsisrdnaknslylqisslraedtavyycarrfverlwgqskpydavdiwgqgt
mvtvsgastkgpsvfplapsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvep

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6xprF (F:)
diqmtqspsslsasvgdrvtitcrasqsisnylnwyqqkpgkapklliyvasnlqsgvps
rfsgsgsgtdfaltisslqpedfasyycqqsyspvttfgggtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >6xprF (F:)
diqmtqspsslsasvgdrvtitcrasqsisnylnwyqqkpgkapklliyvasnlqsgvps
rfsgsgsgtdfaltisslqpedfasyycqqsyspvttfgggtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnr