PDB entry 6xnn

View 6xnn on RCSB PDB site
Description: Crystal Structure of Mouse STING CTD complex with SR-717.
Class: immune system
Keywords: Agonist, Complex, Closed Conformation, Immunity, IMMUNE SYSTEM
Deposited on 2020-07-03, released 2020-08-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-02, with a file datestamp of 2020-08-28.
Experiment type: XRAY
Resolution: 2.49 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Stimulator of interferon genes protein
    Species: Mus musculus [TaxId:10090]
    Gene: Sting1, Eris, Mita, Mpys, Tmem173
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6xnna_
  • Chain 'B':
    Compound: Stimulator of interferon genes protein
    Species: Mus musculus [TaxId:10090]
    Gene: Sting1, Eris, Mita, Mpys, Tmem173
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6xnnb_
  • Heterogens: V67, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6xnnA (A:)
    vahglawsyyigylrlilpglqarirmfnqlhnnmlsgagsrrlyilfpldcgvpdnlsv
    vdpnirfrdmlpqqnidragiknrvysnsvyeilengqpagvcileyatplqtlfamsqd
    akagfsredrleqaklfcrtleeiledvpesrnncrlivyqeptdgnsfslsqevlrhir
    qeekeev
    

    Sequence, based on observed residues (ATOM records): (download)
    >6xnnA (A:)
    ahglawsyyigylrlilpglqarirmfnqlhnnmlsgagsrrlyilfpldcgvpdnlsvv
    dpnirfrdmlpqqnidragiknrvysnsvyeilengqpagvcileyatplqtlfamsqda
    kagfsredrleqaklfcrtleeiledvpesrnncrlivyqeptdgnsfslsqevlrhirq
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6xnnB (B:)
    vahglawsyyigylrlilpglqarirmfnqlhnnmlsgagsrrlyilfpldcgvpdnlsv
    vdpnirfrdmlpqqnidragiknrvysnsvyeilengqpagvcileyatplqtlfamsqd
    akagfsredrleqaklfcrtleeiledvpesrnncrlivyqeptdgnsfslsqevlrhir
    qeekeev
    

    Sequence, based on observed residues (ATOM records): (download)
    >6xnnB (B:)
    ahglawsyyigylrlilpglqarirmfnqlhnnmlsgagsrrlyilfpldcgvpdnlsvv
    dpnirfrdmlpqqnidragiknrvysnsvyeilengqpagvcileyatplqtlfamsqda
    kagfsredrleqaklfcrtleeiledvpesrnncrlivyqeptdgnsfslsqevlrhirq
    e