PDB entry 6xmx

View 6xmx on RCSB PDB site
Description: cryo-em structure of bcl6 bound to bi-3802
Deposited on 2020-07-01, released 2020-11-25
The last revision was dated 2020-12-16, with a file datestamp of 2020-12-11.
Experiment type: EM
Resolution: 3.7 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
  • Heterogens: U52

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6xmxA (A:)
mdwshpqfeksavglndifeaqkiewheggggsgenlyfqgggradsciqftrhasdvll
nlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlkcnlsvinldpeinp
egfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfikaseaemvsaikppr
eeflnsrmlmpqdimayrgcevvennlplrsapgcesrafapslysglstppasysmysh
lpvssllfsdeefrdvrmpvanpfpkeralpcdsarpvpgeysrptlevspnvchsniys
pketipeearsdmhysvaeglkpaapsarnapyfpcdkaskeeerpssedeialhfeppn
aplnrkglvspqspqksdcqpnsptescssknacilqasg

    Sequence, based on observed residues (ATOM records):
    >6xmxA (A:)
sciqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlk
cnlsvinldpeinpegfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfik
as

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6xmxB (B:)
mdwshpqfeksavglndifeaqkiewheggggsgenlyfqgggradsciqftrhasdvll
nlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlkcnlsvinldpeinp
egfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfikaseaemvsaikppr
eeflnsrmlmpqdimayrgcevvennlplrsapgcesrafapslysglstppasysmysh
lpvssllfsdeefrdvrmpvanpfpkeralpcdsarpvpgeysrptlevspnvchsniys
pketipeearsdmhysvaeglkpaapsarnapyfpcdkaskeeerpssedeialhfeppn
aplnrkglvspqspqksdcqpnsptescssknacilqasg

    Sequence, based on observed residues (ATOM records):
    >6xmxB (B:)
sciqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlk
cnlsvinldpeinpegfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfik
as

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6xmxC (C:)
mdwshpqfeksavglndifeaqkiewheggggsgenlyfqgggradsciqftrhasdvll
nlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlkcnlsvinldpeinp
egfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfikaseaemvsaikppr
eeflnsrmlmpqdimayrgcevvennlplrsapgcesrafapslysglstppasysmysh
lpvssllfsdeefrdvrmpvanpfpkeralpcdsarpvpgeysrptlevspnvchsniys
pketipeearsdmhysvaeglkpaapsarnapyfpcdkaskeeerpssedeialhfeppn
aplnrkglvspqspqksdcqpnsptescssknacilqasg

    Sequence, based on observed residues (ATOM records):
    >6xmxC (C:)
sciqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlk
cnlsvinldpeinpegfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfik
as

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6xmxD (D:)
mdwshpqfeksavglndifeaqkiewheggggsgenlyfqgggradsciqftrhasdvll
nlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlkcnlsvinldpeinp
egfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfikaseaemvsaikppr
eeflnsrmlmpqdimayrgcevvennlplrsapgcesrafapslysglstppasysmysh
lpvssllfsdeefrdvrmpvanpfpkeralpcdsarpvpgeysrptlevspnvchsniys
pketipeearsdmhysvaeglkpaapsarnapyfpcdkaskeeerpssedeialhfeppn
aplnrkglvspqspqksdcqpnsptescssknacilqasg

    Sequence, based on observed residues (ATOM records):
    >6xmxD (D:)
sciqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlk
cnlsvinldpeinpegfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfik
as

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6xmxE (E:)
mdwshpqfeksavglndifeaqkiewheggggsgenlyfqgggradsciqftrhasdvll
nlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlkcnlsvinldpeinp
egfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfikaseaemvsaikppr
eeflnsrmlmpqdimayrgcevvennlplrsapgcesrafapslysglstppasysmysh
lpvssllfsdeefrdvrmpvanpfpkeralpcdsarpvpgeysrptlevspnvchsniys
pketipeearsdmhysvaeglkpaapsarnapyfpcdkaskeeerpssedeialhfeppn
aplnrkglvspqspqksdcqpnsptescssknacilqasg

    Sequence, based on observed residues (ATOM records):
    >6xmxE (E:)
sciqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlk
cnlsvinldpeinpegfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfik
as

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6xmxF (F:)
mdwshpqfeksavglndifeaqkiewheggggsgenlyfqgggradsciqftrhasdvll
nlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlkcnlsvinldpeinp
egfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfikaseaemvsaikppr
eeflnsrmlmpqdimayrgcevvennlplrsapgcesrafapslysglstppasysmysh
lpvssllfsdeefrdvrmpvanpfpkeralpcdsarpvpgeysrptlevspnvchsniys
pketipeearsdmhysvaeglkpaapsarnapyfpcdkaskeeerpssedeialhfeppn
aplnrkglvspqspqksdcqpnsptescssknacilqasg

    Sequence, based on observed residues (ATOM records):
    >6xmxF (F:)
sciqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlk
cnlsvinldpeinpegfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfik
as

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6xmxG (G:)
mdwshpqfeksavglndifeaqkiewheggggsgenlyfqgggradsciqftrhasdvll
nlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlkcnlsvinldpeinp
egfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfikaseaemvsaikppr
eeflnsrmlmpqdimayrgcevvennlplrsapgcesrafapslysglstppasysmysh
lpvssllfsdeefrdvrmpvanpfpkeralpcdsarpvpgeysrptlevspnvchsniys
pketipeearsdmhysvaeglkpaapsarnapyfpcdkaskeeerpssedeialhfeppn
aplnrkglvspqspqksdcqpnsptescssknacilqasg

    Sequence, based on observed residues (ATOM records):
    >6xmxG (G:)
sciqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlk
cnlsvinldpeinpegfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfik
as

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6xmxH (H:)
mdwshpqfeksavglndifeaqkiewheggggsgenlyfqgggradsciqftrhasdvll
nlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlkcnlsvinldpeinp
egfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfikaseaemvsaikppr
eeflnsrmlmpqdimayrgcevvennlplrsapgcesrafapslysglstppasysmysh
lpvssllfsdeefrdvrmpvanpfpkeralpcdsarpvpgeysrptlevspnvchsniys
pketipeearsdmhysvaeglkpaapsarnapyfpcdkaskeeerpssedeialhfeppn
aplnrkglvspqspqksdcqpnsptescssknacilqasg

    Sequence, based on observed residues (ATOM records):
    >6xmxH (H:)
sciqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlk
cnlsvinldpeinpegfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfik
as