PDB entry 6xmo

View 6xmo on RCSB PDB site
Description: Human aldolase A I98F
Class: lyase
Keywords: rheostat, allosterism, LYASE
Deposited on 2020-06-30, released 2021-07-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-07, with a file datestamp of 2021-07-02.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fructose-bisphosphate aldolase A
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDOA, ALDA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04075 (0-363)
      • engineered mutation (97)
    Domains in SCOPe 2.08: d6xmoa_
  • Chain 'B':
    Compound: Fructose-bisphosphate aldolase A
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDOA, ALDA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04075 (0-363)
      • engineered mutation (97)
    Domains in SCOPe 2.08: d6xmob_
  • Heterogens: PO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6xmoA (A:)
mpyqypaltpeqkkelsdiahrivapgkgilaadestgsiakrlqsigtenteenrrfyr
qllltaddrvnpciggvilfhetlyqkaddgrpfpqvfkskggvvgikvdkgvvplagtn
getttqgldglsercaqykkdgadfakwrcvlkigehtpsalaimenanvlaryasicqq
ngivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhiylegtllkpnmvtpghac
tqkfsheeiamatvtalrrtvppavtgitflsggqseeeasinlnainkcpllkpwaltf
sygralqasalkawggkkenlkaaqeeyvkralanslacqgkytpsgqagaaaseslfvs
nhay

    Sequence, based on observed residues (ATOM records): (download) 
    >6xmoA (A:)
altpeqkkelsdiahrivapgkgilaadestgsiakrlqsigtenteenrrfyrqlllta
ddrvnpciggvilfhetlyqkaddgrpfpqvfkskggvvgikvdkgvvplagtngetttq
gldglsercaqykkdgadfakwrcvlkigehtpsalaimenanvlaryasicqqngivpi
vepeilpdgdhdlkrcqyvtekvlaavykalsdhhiylegtllkpnmvtpghactqkfsh
eeiamatvtalrrtvppavtgitflsggqseeeasinlnainkcpllkpwaltfsygral
qasalkawggkkenlkaaqeeyvkralanslacqgkytpaaaseslfvsnhay

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6xmoB (B:)
mpyqypaltpeqkkelsdiahrivapgkgilaadestgsiakrlqsigtenteenrrfyr
qllltaddrvnpciggvilfhetlyqkaddgrpfpqvfkskggvvgikvdkgvvplagtn
getttqgldglsercaqykkdgadfakwrcvlkigehtpsalaimenanvlaryasicqq
ngivpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhiylegtllkpnmvtpghac
tqkfsheeiamatvtalrrtvppavtgitflsggqseeeasinlnainkcpllkpwaltf
sygralqasalkawggkkenlkaaqeeyvkralanslacqgkytpsgqagaaaseslfvs
nhay

    Sequence, based on observed residues (ATOM records): (download) 
    >6xmoB (B:)
altpeqkkelsdiahrivapgkgilaadestgsiakrlqsigtenteenrrfyrqlllta
ddrvnpciggvilfhetlyqkaddgrpfpqvfkskggvvgikvdkgvvplagtngetttq
gldglsercaqykkdgadfakwrcvlkigehtpsalaimenanvlaryasicqqngivpi
vepeilpdgdhdlkrcqyvtekvlaavykalsdhhiylegtllkpnmvtpghactqkfsh
eeiamatvtalrrtvppavtgitflsggqseeeasinlnainkcpllkpwaltfsygral
qasalkawggkkenlkaaqeeyvkralanslacqgkytpaaaseslfvsnhay