PDB entry 6xlw

View 6xlw on RCSB PDB site
Description: crystal structure of u2af65 bound to adml splice site sequence
Deposited on 2020-06-29, released 2020-10-07
The last revision was dated 2022-03-16, with a file datestamp of 2022-03-11.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.57 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: splicing factor u2af 65 kda subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: U2AF2, U2AF65
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26368 (3-203)
      • expression tag (0-2)
  • Chain 'B':
    Compound: DNA/RNA (5'-r(p*up*up*(ud)p*up*u)-d(p*(bru))-r(p*cp*c)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Heterogens: GOL, PEG, NA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6xlwA (A:)
    gplgsqmtrqarrlyvgnipfgiteeammdffnaqmrlggltqapgnpvlavqinqdknf
    aflefrsvdettqamafdgiifqgqslkirrphdyqplpgmsenpsvyvpgvvstvvpds
    ahklfigglpnylnddqvkelltsfgplkafnlvkdsatglskgyafceyvdinvtdqai
    aglngmqlgdkkllvqrasvgakn
    

    Sequence, based on observed residues (ATOM records):
    >6xlwA (A:)
    sqmtrqarrlyvgnipfgiteeammdffnaqmrlggltqapgnpvlavqinqdknfafle
    frsvdettqamafdgiifqgqslkirrphdyqplpgmsenpsvyvpgvvstvvpdsahkl
    figglpnylnddqvkelltsfgplkafnlvkdsatglskgyafceyvdinvtdqaiagln
    gmqlgdkkllvqrasvgak
    

  • Chain 'B':
    No sequence available.