PDB entry 6xkp

View 6xkp on RCSB PDB site
Description: Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CV07-270
Class: viral protein/immune system
Keywords: SARS-CoV-2, Antibody, Spike, Coronavirus, COVID-19, IMMUNE SYSTEM, VIRAL PROTEIN-IMMUNE SYSTEM complex
Deposited on 2020-06-26, released 2020-10-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-11-25, with a file datestamp of 2020-11-20.
Experiment type: XRAY
Resolution: 2.72 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Spike protein S1
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6xkpa_
  • Chain 'B':
    Compound: Spike protein S1
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6xkpb_
  • Chain 'H':
    Compound: CV07-270 Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6XKP (0-End)
    Domains in SCOPe 2.08: d6xkph_
  • Chain 'L':
    Compound: CV07-270 Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6XKP
    Domains in SCOPe 2.08: d6xkpl1, d6xkpl2
  • Chain 'M':
    Compound: CV07-270 Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6XKP (0-End)
    Domains in SCOPe 2.08: d6xkpm_
  • Chain 'N':
    Compound: CV07-270 Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6XKP
    Domains in SCOPe 2.08: d6xkpn1, d6xkpn2
  • Heterogens: NAG, SO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6xkpA (A:)
rvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfk
cygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawns
nnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfq
ptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvnfsghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6xkpA (A:)
nlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcft
nvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynyly
rlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpyrvvvl
sfellhapatvcgp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6xkpB (B:)
rvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfk
cygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawns
nnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfq
ptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvnfsghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6xkpB (B:)
nlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcft
nvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynyly
rlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpyrvvvl
sfellhapatvcgp

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6xkpH (H:)
qvqlvesggglvkpggslrlscaasgftfsdyymtwirqapgkglewvsyisssgstiyy
adsvkgrftisrdnaknslylqmnslraedtavyycarargssgwyrigtrwgnwfdpwg
qgtlvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvh
tfpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

    Sequence, based on observed residues (ATOM records): (download) 
    >6xkpH (H:)
qvqlvesggglvkpggslrlscaasgftfsdyymtwirqapgkglewvsyisssgstiyy
adsvkgrftisrdnaknslylqmnslraedtavyycarargssgwyrigtrwgnwfdpwg
qgtlvtvssastkgpsvfplapalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6xkpL (L:)
qsaltqpasvsgspgqsitisctgtssdvggynyvswyqqhpgkapklmiyevsnrpsgv
snrfsgsksgntasltisglqaedeadyycssytsssnvvfgggtmltvlgqpkaapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >6xkpL (L:)
altqpasvsgspgqsitisctgtssdvggynyvswyqqhpgkapklmiyevsnrpsgvsn
rfsgsksgntasltisglqaedeadyycssytsssnvvfgggtmltvlgqpkaapsvtlf
ppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassyl
sltpeqwkshrsyscqvthegstvektvapt

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >6xkpM (M:)
qvqlvesggglvkpggslrlscaasgftfsdyymtwirqapgkglewvsyisssgstiyy
adsvkgrftisrdnaknslylqmnslraedtavyycarargssgwyrigtrwgnwfdpwg
qgtlvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvh
tfpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

    Sequence, based on observed residues (ATOM records): (download) 
    >6xkpM (M:)
qvqlvesggglvkpggslrlscaasgftfsdyymtwirqapgkglewvsyisssgstiyy
adsvkgrftisrdnaknslylqmnslraedtavyycarargssgwyrigtrwgnwfdpwg
qgtlvtvssastkgpsvfplaptstaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'N':
    Sequence, based on SEQRES records: (download) 
    >6xkpN (N:)
qsaltqpasvsgspgqsitisctgtssdvggynyvswyqqhpgkapklmiyevsnrpsgv
snrfsgsksgntasltisglqaedeadyycssytsssnvvfgggtmltvlgqpkaapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >6xkpN (N:)
altqpasvsgspgqsitisctgtssdvggynyvswyqqhpgkapklmiyevsnrpsgvsn
rfsgsksgntasltisglqaedeadyycssytsssnvvfgggtmltvlgqpkaapsvtlf
ppsseelqankatlvclisdfypgavtvawkdsspvkagvetttpskqsnnkyaassyls
ltpeqwkshrsyscqvthegstvektvapt