PDB entry 6xec

View 6xec on RCSB PDB site
Description: structure of human hdac2 in complex with ketone inhibitor (compound o)
Deposited on 2020-06-12, released 2020-08-12
The last revision was dated 2020-08-12, with a file datestamp of 2020-08-07.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone deacetylase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: HDAC2
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Histone deacetylase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: HDAC2
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Histone deacetylase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: HDAC2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: V1S, ZN, SO4, CA, PEG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6xecA (A:)
maysqgggkkkvcyyydgdignyyygqghpmkphrirmthnlllnyglyrkmeiyrphka
taeemtkyhsdeyikflrsirpdnmseyskqmqrfnvgedcpvfdglfefcqlstggsva
gavklnrqqtdmavnwagglhhakkseasgfcyvndivlailellkyhqrvlyididihh
gdgveeafyttdrvmtvsfhkygeyfpgtgdlrdigagkgkyyavnfpmrdgiddesygq
ifkpiiskvmemyqpsavvlqcgadslsgdrlgcfnltvkghakcvevvktfnlpllmlg
gggytirnvarcwtyetavaldceipnelpyndyfeyfgpdfklhispsnmtnqntpeym
ekikqrlfenlrmlph

    Sequence, based on observed residues (ATOM records):
    >6xecA (A:)
gkkkvcyyydgdignyyygqghpmkphrirmthnlllnyglyrkmeiyrphkataeemtk
yhsdeyikflrsirpdnmseyskqmqrfnvgedcpvfdglfefcqlstggsvagavklnr
qqtdmavnwagglhhakkseasgfcyvndivlailellkyhqrvlyididihhgdgveea
fyttdrvmtvsfhkygeyfpgtgdlrdigagkgkyyavnfpmrdgiddesygqifkpiis
kvmemyqpsavvlqcgadslsgdrlgcfnltvkghakcvevvktfnlpllmlggggytir
nvarcwtyetavaldceipnelpyndyfeyfgpdfklhispsnmtnqntpeymekikqrl
fenlrmlp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6xecB (B:)
maysqgggkkkvcyyydgdignyyygqghpmkphrirmthnlllnyglyrkmeiyrphka
taeemtkyhsdeyikflrsirpdnmseyskqmqrfnvgedcpvfdglfefcqlstggsva
gavklnrqqtdmavnwagglhhakkseasgfcyvndivlailellkyhqrvlyididihh
gdgveeafyttdrvmtvsfhkygeyfpgtgdlrdigagkgkyyavnfpmrdgiddesygq
ifkpiiskvmemyqpsavvlqcgadslsgdrlgcfnltvkghakcvevvktfnlpllmlg
gggytirnvarcwtyetavaldceipnelpyndyfeyfgpdfklhispsnmtnqntpeym
ekikqrlfenlrmlph

    Sequence, based on observed residues (ATOM records):
    >6xecB (B:)
kkvcyyydgdignyyygqghpmkphrirmthnlllnyglyrkmeiyrphkataeemtkyh
sdeyikflrsirpdnmseyskqmqrfnvgedcpvfdglfefcqlstggsvagavklnrqq
tdmavnwagglhhakkseasgfcyvndivlailellkyhqrvlyididihhgdgveeafy
ttdrvmtvsfhkygeyfpgtgdlrdigagkgkyyavnfpmrdgiddesygqifkpiiskv
memyqpsavvlqcgadslsgdrlgcfnltvkghakcvevvktfnlpllmlggggytirnv
arcwtyetavaldceipnelpyndyfeyfgpdfklhispsnmtnqntpeymekikqrlfe
nlrmlp

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6xecC (C:)
maysqgggkkkvcyyydgdignyyygqghpmkphrirmthnlllnyglyrkmeiyrphka
taeemtkyhsdeyikflrsirpdnmseyskqmqrfnvgedcpvfdglfefcqlstggsva
gavklnrqqtdmavnwagglhhakkseasgfcyvndivlailellkyhqrvlyididihh
gdgveeafyttdrvmtvsfhkygeyfpgtgdlrdigagkgkyyavnfpmrdgiddesygq
ifkpiiskvmemyqpsavvlqcgadslsgdrlgcfnltvkghakcvevvktfnlpllmlg
gggytirnvarcwtyetavaldceipnelpyndyfeyfgpdfklhispsnmtnqntpeym
ekikqrlfenlrmlph

    Sequence, based on observed residues (ATOM records):
    >6xecC (C:)
kkvcyyydgdignyyygqghpmkphrirmthnlllnyglyrkmeiyrphkataeemtkyh
sdeyikflrsirpdnmseyskqmqrfnvgedcpvfdglfefcqlstggsvagavklnrqq
tdmavnwagglhhakkseasgfcyvndivlailellkyhqrvlyididihhgdgveeafy
ttdrvmtvsfhkygeyfpgtgdlrdigagkgkyyavnfpmrdgiddesygqifkpiiskv
memyqpsavvlqcgadslsgdrlgcfnltvkghakcvevvktfnlpllmlggggytirnv
arcwtyetavaldceipnelpyndyfeyfgpdfklhispsnmtnqntpeymekikqrlfe
nlrmlp