PDB entry 6xdd

View 6xdd on RCSB PDB site
Description: crystal structure of ire1 in complex with g-3053
Deposited on 2020-06-10, released 2021-04-21
The last revision was dated 2021-04-21, with a file datestamp of 2021-04-16.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase/endoribonuclease IRE1
    Species: Homo sapiens [TaxId:9606]
    Gene: ERN1, IRE1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Serine/threonine-protein kinase/endoribonuclease IRE1
    Species: Homo sapiens [TaxId:9606]
    Gene: ERN1, IRE1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: N97, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6xddA (A:)
gsspsleqddgdeetsvvivgkisfcpkdvlghgaegtivyrgmfdnrdvavkrilpecf
sfadrevqllresdehpnviryfctekdrqfqyiaielcaatlqeyveqkdfahlglepi
tllqqttsglahlhslnivhrdlkphnilismpnahgkikamisdfglckklavgrhsfs
rrsgvpgtegwiapemlsedckenptytvdifsagcvfyyvisegshpfgkslqrqanil
lgacsldclhpekhedviareliekmiamdpqkrpsakhvlkhpffwslekqlqffqdvs
driekesldgpivkqlerggravvkmdwrenitvplqtdlrkfrtykggsvrdllramrn
kkhhyrelpaevretlgslpddfvcyftsrfphllahtyramelcsherlfqpyyfhepp
epqppvtpdalgns

    Sequence, based on observed residues (ATOM records):
    >6xddA (A:)
etsvvivgkisfcpkdvlghgaegtivyrgmfdnrdvavkrilpecfsfadrevqllres
dehpnviryfctekdrqfqyiaielcaatlqeyveqkdfahlglepitllqqttsglahl
hslnivhrdlkphnilismpnahgkikamisdfglckklavgrhsfsrrsgvpgtegwia
pemlsedckenptytvdifsagcvfyyvisegshpfgkslqrqanillgacsldclhpek
hedviareliekmiamdpqkrpsakhvlkhpffwslekqlqffqdvsdriekesldgpiv
kqlerggravvkmdwrenitvplqtdlrkfrtykggsvrdllramrnkkhhyrelpaevr
etlgslpddfvcyftsrfphllahtyramelcsherlfqpyyfh

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6xddB (B:)
gsspsleqddgdeetsvvivgkisfcpkdvlghgaegtivyrgmfdnrdvavkrilpecf
sfadrevqllresdehpnviryfctekdrqfqyiaielcaatlqeyveqkdfahlglepi
tllqqttsglahlhslnivhrdlkphnilismpnahgkikamisdfglckklavgrhsfs
rrsgvpgtegwiapemlsedckenptytvdifsagcvfyyvisegshpfgkslqrqanil
lgacsldclhpekhedviareliekmiamdpqkrpsakhvlkhpffwslekqlqffqdvs
driekesldgpivkqlerggravvkmdwrenitvplqtdlrkfrtykggsvrdllramrn
kkhhyrelpaevretlgslpddfvcyftsrfphllahtyramelcsherlfqpyyfhepp
epqppvtpdalgns

    Sequence, based on observed residues (ATOM records):
    >6xddB (B:)
etsvvivgkisfcpkdvlghgaegtivyrgmfdnrdvavkrilpecfsfadrevqllres
dehpnviryfctekdrqfqyiaielcaatlqeyveqkdfahlglepitllqqttsglahl
hslnivhrdlkphnilismpnahgkikamisdfglckklavgrhsfsrrsgvpgtegwia
pemlsedckenptytvdifsagcvfyyvisegshpfgkslqrqanillgacsldclhpek
hedviareliekmiamdpqkrpsakhvlkhpffwslekqlqffqdvsdriekesldgpiv
kqlerggravvkmdwrenitvplqtdlrkfrtykggsvrdllramrnkkhhyrelpaevr
etlgslpddfvcyftsrfphllahtyramelcsherlfqpyyfh