PDB entry 6xco

View 6xco on RCSB PDB site
Description: Immune receptor complex
Class: immune system
Keywords: Complex, IMMUNE SYSTEM
Deposited on 2020-06-08, released 2021-07-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-14, with a file datestamp of 2021-07-09.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: MHC class II HLA-DQ-alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-DQA1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q30069 (0-183)
      • engineered mutation (74)
      • expression tag (184-192)
    Domains in SCOPe 2.08: d6xcoa1, d6xcoa2
  • Chain 'B':
    Compound: Hybrid Insulin Peptide, MHC class II HLA-DQ-beta-1 fusion
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-DQB1
    Database cross-references and differences (RAF-indexed):
    • PDB 6XCO (0-14)
      • linker (15-29)
    • Uniprot O19707 (30-221)
      • expression tag (222-229)
  • Chain 'D':
    Compound: T-CELL-RECEPTOR, A1.9-alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TRAV20*02
    Database cross-references and differences (RAF-indexed):
    • PDB 6XCO (0-204)
  • Chain 'E':
    Compound: T-CELL-RECEPTOR, A1.9-beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TRBV5-1*01
    Database cross-references and differences (RAF-indexed):
    • PDB 6XCO (0-239)
    Domains in SCOPe 2.08: d6xcoe1, d6xcoe2
  • Heterogens: NAG, GOL, CAC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6xcoA (A:)
edivadhvasygvnlyqsygpsgqyshefdgdeefyvdlerketvwqlplfrrfrrfdpq
faltniavlkhnlncvikrsnstaatnevpevtvfskspvtlgqpntliclvdnifppvv
nitwlsnghsvtegvsetsflsksdhsffkisyltflpsadeiydckvehwgldepllkh
wepestggddddk

    Sequence, based on observed residues (ATOM records): (download) 
    >6xcoA (A:)
divadhvasygvnlyqsygpsgqyshefdgdeefyvdlerketvwqlplfrrfrrfdpqf
altniavlkhnlncvikrsnstaatnevpevtvfskspvtlgqpntliclvdnifppvvn
itwlsnghsvtegvsetsflsksdhsffkisyltflpsadeiydckvehwgldepllkhw
ep

  • Chain 'B':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6xcoE (E:)
mgvtqtpryliktrgqqvtlscspisghrsvswyqqtpgqglqflfeyfsetqrnkgnfp
grfsgrqfsnsrsemnvstlelgdsalylcasslerdgytfgsgtrltvvedlnkvfppe
vavfepseaeishtqkatlvclatgffpdhvelswwvngkevhsgvctdpqplkeqpaln
dsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >6xcoE (E:)
gvtqtpryliktrgqqvtlscspisghrsvswyqqtpgqglqflfeyfsetqrnkgnfpg
rfsgrqfsnsrsemnvstlelgdsalylcasslerdgytfgsgtrltvvedlnkvfppev
avfepseaeishtqkatlvclatgffpdhvelswwvngkevhsgvctdpqplkeqpalnd
sryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgra