PDB entry 6xca

View 6xca on RCSB PDB site
Description: Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C105
Class: immune system
Keywords: Antibody, SARS-CoV-2, SARS2, Coronavirus, Neutralizing, IMMUNE SYSTEM
Deposited on 2020-06-08, released 2020-07-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-02, with a file datestamp of 2020-08-28.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: C105 Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6XCA
    Domains in SCOPe 2.08: d6xcah_
  • Chain 'L':
    Compound: C105 Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6XCA
    Domains in SCOPe 2.08: d6xcal1, d6xcal2
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6xcaH (H:)
qvqlvesgggliqpggslrlscaasgftvssnymswvrqapgkglewvsviysggstyya
dsvkgrftisrdnskntlylqmnslraedtavyycargegwelpydywgqgtlvtvssas
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkthhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6xcaH (H:)
vqlvesgggliqpggslrlscaasgftvssnymswvrqapgkglewvsviysggstyyad
svkgrftisrdnskntlylqmnslraedtavyycargegwelpydywgqgtlvtvssast
kgpsvfplapggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvv
tvpssslgtqtyicnvnhkpsntkvdkrvep

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6xcaL (L:)
qsaltqppsgsgspgqsvtisctgtssdvggykyvswyqqhpgkapklmiyevskrpsgv
pdrfsgsksgntasltvsglqaedeadyycssyegsnnfvvfgggtkltvlgqpkaapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >6xcaL (L:)
altqppsgsgspgqsvtisctgtssdvggykyvswyqqhpgkapklmiyevskrpsgvpd
rfsgsksgntasltvsglqaedeadyycssyegsnnfvvfgggtkltvlgqpkaapsvtl
fppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassy
lsltpeqwkshrsyscqvthegstvektvap