PDB entry 6xar

View 6xar on RCSB PDB site
Description: Structure of CBL tyrosine kinase binding domain (TKBD) with C-terminal tail of Src-like kinase protein 2 (SLAP2)
Class: signaling protein
Keywords: adaptor, E3 ubiquitin ligase, activation, complex, SIGNALING PROTEIN
Deposited on 2020-06-04, released 2021-03-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-03-03, with a file datestamp of 2021-02-26.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: E3 ubiquitin-protein ligase CBL
    Species: Homo sapiens [TaxId:9606]
    Gene: CBL, CBL2, RNF55
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6xara1, d6xara2, d6xara3
  • Chain 'B':
    Compound: E3 ubiquitin-protein ligase CBL
    Species: Homo sapiens [TaxId:9606]
    Gene: CBL, CBL2, RNF55
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6xarb1, d6xarb2, d6xarb3
  • Chain 'C':
    Compound: Src-like-adapter 2
    Species: Mus musculus [TaxId:10090]
    Gene: Sla2
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Src-like-adapter 2
    Species: Mus musculus [TaxId:10090]
    Gene: Sla2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6xarA (A:)
gsliglmkdafqphhhhhhhlsphppgtvdkkmvekcwklmdkvvrlcqnpklalknspp
yildllpdtyqhlrtilsryegkmetlgeneyfrvfmenlmkktkqtislfkegkermye
ensqprrnltklslifshmlaelkgifpsglfqgdtfritkadaaefwrkafgektivpw
ksfrqalhevhpissgleamalkstidltcndyisvfefdiftrlfqpwssllrnwnsla
vthpgymafltydevkarlqkfihkpgsyifrlsctrlgqwaigyvtadgnilqtiphnk
plfqalidgfregfylfpdgrnqnpdltglceptp

    Sequence, based on observed residues (ATOM records): (download) 
    >6xarA (A:)
pgtvdkkmvekcwklmdkvvrlcqnpklalknsppyildllpdtyqhlrtilsryegkme
tlgeneyfrvfmenlmkktkqtislfkegkermyeensqprrnltklslifshmlaelkg
ifpsglfqgdtfritkadaaefwrkafgektivpwksfrqalhevhpissgleamalkst
idltcndyisvfefdiftrlfqpwssllrnwnslavthpgymafltydevkarlqkfihk
pgsyifrlsctrlgqwaigyvtadgnilqtiphnkplfqalidgfregfylfpdgrnqnp
dltgl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6xarB (B:)
gsliglmkdafqphhhhhhhlsphppgtvdkkmvekcwklmdkvvrlcqnpklalknspp
yildllpdtyqhlrtilsryegkmetlgeneyfrvfmenlmkktkqtislfkegkermye
ensqprrnltklslifshmlaelkgifpsglfqgdtfritkadaaefwrkafgektivpw
ksfrqalhevhpissgleamalkstidltcndyisvfefdiftrlfqpwssllrnwnsla
vthpgymafltydevkarlqkfihkpgsyifrlsctrlgqwaigyvtadgnilqtiphnk
plfqalidgfregfylfpdgrnqnpdltglceptp

    Sequence, based on observed residues (ATOM records): (download) 
    >6xarB (B:)
dkkmvekcwklmdkvvrlcqnpklalknsppyildllpdtyqhlrtilsryegkmetlge
neyfrvfmenlmkktkqtislfkegkermyeensqprrnltklslifshmlaelkgifps
glfqgdtfritkadaaefwrkafgektivpwksfrqalhevhpissgleamalkstidlt
cndyisvfefdiftrlfqpwssllrnwnslavthpgymafltydevkarlqkfihkpgsy
ifrlsctrlgqwaigyvtadgnilqtiphnkplfqalidgfregfylfpdgrnqnpdltg

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.