PDB entry 6xaa
View 6xaa on RCSB PDB site
Description: SARS CoV-2 PLpro in complex with ubiquitin propargylamide
Class: hydrolase/substrate
Keywords: SARS CoV-2, papain-like protease, ubiquitin activity based probe, COVID19, HYDROLASE-SUBSTRATE complex
Deposited on
2020-06-04, released
2020-06-17
The last revision prior to the SCOPe 2.08 freeze date was dated
2021-01-27, with a file datestamp of
2021-01-22.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.27
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: non-structural protein 3
Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
Gene: rep, 1a-1b
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6xaaa1, d6xaaa2 - Chain 'B':
Compound: Ubiquitin-propargylamide
Species: Homo sapiens [TaxId:9606]
Gene: UBB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6xaab_ - Heterogens: ZN, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6xaaA (A:)
gtrevrtikvfttvdninlhtqvvdmsmtygqqfgptyldgadvtkikphnshegktfyv
lpnddtlrveafeyyhttdpsflgrymsalnhtkkwkypqvngltsikwadnncylatal
ltlqqielkfnppalqdayyrarageaanfcalilaycnktvgelgdvretmsylfqhan
ldsckrvlnvvcktcgqqqttlkgveavmymgtlsyeqfkkgvqipctcgkqatkylvqq
espfvmmsappaqyelkhgtftcaseytgnyqcghykhitsketlycidgalltksseyk
gpitdvfykensytttik
Sequence, based on observed residues (ATOM records): (download)
>6xaaA (A:)
ikvfttvdninlhtqvvdmsmtygqqfgptyldgadvtkikphnshegktfyvlpnddtl
rveafeyyhttdpsflgrymsalnhtkkwkypqvngltsikwadnncylatalltlqqie
lkfnppalqdayyrarageaanfcalilaycnktvgelgdvretmsylfqhanldsckrv
lnvvcktcgqqqttlkgveavmymgtlsyeqfkkgvqipctcgkqatkylvqqespfvmm
sappaqyelkhgtftcaseytgnyqcghykhitsketlycidgalltksseykgpitdvf
ykensyttt
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>6xaaB (B:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgx