PDB entry 6x93

View 6x93 on RCSB PDB site
Description: interleukin-10 signaling complex with il-10ra and il-10rb
Deposited on 2020-06-02, released 2021-03-17
The last revision was dated 2021-03-31, with a file datestamp of 2021-03-26.
Experiment type: EM
Resolution: 3.5 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: interleukin-10
    Species: Homo sapiens [TaxId:9606]
    Gene: IL10
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22301 (Start-159)
      • conflict (17)
      • conflict (91)
      • conflict (99)
      • conflict (103)
  • Chain 'B':
    Compound: Interleukin-10 receptor subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: IL10RA, IL10R
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Interleukin-10 receptor subunit beta
    Species: Homo sapiens [TaxId:9606]
    Gene: IL10RB, CRFB4, D21S58, D21S66
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q08334
      • conflict (29)
      • conflict (48)
      • conflict (82)
  • Chain 'D':
    Compound: interleukin-10
    Species: Homo sapiens [TaxId:9606]
    Gene: IL10
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22301 (Start-159)
      • conflict (17)
      • conflict (91)
      • conflict (99)
      • conflict (103)
  • Chain 'E':
    Compound: Interleukin-10 receptor subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: IL10RA, IL10R
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Interleukin-10 receptor subunit beta
    Species: Homo sapiens [TaxId:9606]
    Gene: IL10RB, CRFB4, D21S58, D21S66
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q08334
      • conflict (29)
      • conflict (48)
      • conflict (82)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6x93A (A:)
spgqgtqsenscthfpgylpnmlrdlrdafsrvktffqmkdqldnlllkeslledfkgyl
gcqalsemiqfyleevmpqaenqdpdikahvqslgenlkdlrlwlrrchrflpcenkska
veqvknafnklqekgiykamsefdifinyieaymtmkirn

    Sequence, based on observed residues (ATOM records):
    >6x93A (A:)
cthfpgylpnmlrdlrdafsrvktffqmkdqldnlllkeslledfkgylgcqalsemiqf
yleevmpqaenqdpdikahvqslgenlkdlrlwlrrchrknafnklqekgiykamsefdi
finyieaymtmkirn

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6x93B (B:)
hgtelpsppsvwfeaeffhhilhwtpipnqsestcyevallrygieswnsisncsqtlsy
dltavtldlyhsngyrarvravdgsrhsnwtvtntrfsvdevtltvgsvnleihngfilg
kiqlprpkmapandtyesifshfreyeiairkvpgnftfthkkvkhenfslltsgevgef
cvqvkpsvasrsnkgmwskeecisltrqyftvtn

    Sequence, based on observed residues (ATOM records):
    >6x93B (B:)
elpsppsvwfeaeffhhilhwtpipnqsestcyevallrygieswnsisncsqtlsydlt
avtldlyhsngyrarvravdgsrhsnwtvtntrfsvdevtltvgsvnleihngfilgkiq
lprpkmapandtyesifshfreyeiairkvpthkkvkhenfslltsgevgefcvqvkpsv
asrsnkgmwskeecislt

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6x93C (C:)
mvpppenvrmnsvnfknilqwespafakgqltftaqylsyrifqdkcmqttltecdfssl
skygdhtlrvraefadehsdwvqitfcpvddtiigppgmqvevladslhmrflapkiene
yetwtmknvynswtynvqywkngtdekfqitpqydfevlrnlepwttycvqvrgflpdrn
kagewsepvceqtthdetvps

    Sequence, based on observed residues (ATOM records):
    >6x93C (C:)
vpppenvrmnsvnfknilqwespafakgqltftaqylsyrifqdkcmqttltecdfssls
kygdhtlrvraefadehsdwvqitfcpvddtiigppgmqvevladslhmrflapkieney
etwtmknvynswtynvqywqitpqydfevlepwttycvqvrgflpdrnkagewsepvceq
tth

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6x93D (D:)
spgqgtqsenscthfpgylpnmlrdlrdafsrvktffqmkdqldnlllkeslledfkgyl
gcqalsemiqfyleevmpqaenqdpdikahvqslgenlkdlrlwlrrchrflpcenkska
veqvknafnklqekgiykamsefdifinyieaymtmkirn

    Sequence, based on observed residues (ATOM records):
    >6x93D (D:)
cthfpgylpnmlrdlrdafsrvktffqmkdqldnlllkeslledfkgylgcqalsemiqf
yleevmpqaenqdpdikahvqslgenlkdlrlwlrrlpcenkskaveqvknafnklqekg
iykamsefdifinyieaymtmkirn

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6x93E (E:)
hgtelpsppsvwfeaeffhhilhwtpipnqsestcyevallrygieswnsisncsqtlsy
dltavtldlyhsngyrarvravdgsrhsnwtvtntrfsvdevtltvgsvnleihngfilg
kiqlprpkmapandtyesifshfreyeiairkvpgnftfthkkvkhenfslltsgevgef
cvqvkpsvasrsnkgmwskeecisltrqyftvtn

    Sequence, based on observed residues (ATOM records):
    >6x93E (E:)
elpsppsvwfeaeffhhilhwtpipnqsestcyevallrygieswnsisncsqtlsydlt
avtldlyhsngyrarvravdgsrhsnwtvtntrfsvdevtltvgsvnleihngfilgkiq
lprpkmapandtyesifshfreyeiairkvpthkkvkhenfslltsgevgefcvqvkpsv
asrsnkgmwskeecislt

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6x93F (F:)
mvpppenvrmnsvnfknilqwespafakgqltftaqylsyrifqdkcmqttltecdfssl
skygdhtlrvraefadehsdwvqitfcpvddtiigppgmqvevladslhmrflapkiene
yetwtmknvynswtynvqywkngtdekfqitpqydfevlrnlepwttycvqvrgflpdrn
kagewsepvceqtthdetvps

    Sequence, based on observed residues (ATOM records):
    >6x93F (F:)
vpppenvrmnsvnfknilqwespafakgqltftaqylsyrifqdkcmqttltecdfssls
kygdhtlrvraefadehsdwvqitfcpvddtiigppgmqvevladslhmrflapkieney
etwtmknvynswtynvqywqitpqydfevlepwttycvqvrgflpdrnkagewsepvceq
tth