PDB entry 6x78

View 6x78 on RCSB PDB site
Description: vaccine-elicited mouse fp-targeting neutralizing antibody vfp48.03 in complex with hiv fusion peptide (residue 512-519)
Deposited on 2020-05-29, released 2021-06-02
The last revision was dated 2021-06-02, with a file datestamp of 2021-05-28.
Experiment type: XRAY
Resolution: 2.36 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: antibody vFP48.03 light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6X78 (0-End)
  • Chain 'B':
    Compound: antibody vFP48.03 heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6X78 (0-End)
  • Chain 'G':
    Compound: HIV fusion peptide 512-519 V2
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • PDB 6X78 (0-End)
  • Chain 'H':
    Compound: antibody vFP48.03 heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6X78 (0-End)
  • Chain 'I':
    Compound: HIV fusion peptide 512-519 V2
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • PDB 6X78 (0-End)
  • Chain 'L':
    Compound: antibody vFP48.03 light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6X78 (0-End)
  • Heterogens: SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6x78A (A:)
dvvmtqtaltlsvtigqpasisckssqslldsdgktylnwllqrpgqspkrliylvskld
sgvpdrftgsgsgtdftlkisrveaedlgvyycwqgthfpqtfgggtrleikrtdaaptv
sifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysm
sstltltkdeyerhnsytceathktstspivksfnrnec

    Sequence, based on observed residues (ATOM records):
    >6x78A (A:)
dvvmtqtaltlsvtigqpasisckssqslldsdgktylnwllqrpgqspkrliylvskld
sgvpdrftgsgsgtdftlkisrveaedlgvyycwqgthfpqtfgggtrleikrtdaaptv
sifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysm
sstltltkdeyerhnsytceathktstspivksfnrne

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6x78B (B:)
qvqlqqpgaefvkpgasvrmsckasgytftsywiawvkqrpgqglewigdiypgsgytny
ngklknratltvdtssntaymqlssltsedsavyyctrggttfvaepwlaywgqgtlvav
saasttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlq
sdlytlsssvtvpsstwpsetvtcnvahpasstkvdkkivprdcdkglevlfqg

    Sequence, based on observed residues (ATOM records):
    >6x78B (B:)
qvqlqqpgaefvkpgasvrmsckasgytftsywiawvkqrpgqglewigdiypgsgytny
ngklknratltvdtssntaymqlssltsedsavyyctrggttfvaepwlaywgqgtlvav
saasttppsvyplapgnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlyt
lsssvtvpsstwpsetvtcnvahpasstkvdkkivprd

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6x78G (G:)
avglgavf

    Sequence, based on observed residues (ATOM records):
    >6x78G (G:)
avglg

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6x78H (H:)
qvqlqqpgaefvkpgasvrmsckasgytftsywiawvkqrpgqglewigdiypgsgytny
ngklknratltvdtssntaymqlssltsedsavyyctrggttfvaepwlaywgqgtlvav
saasttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlq
sdlytlsssvtvpsstwpsetvtcnvahpasstkvdkkivprdcdkglevlfqg

    Sequence, based on observed residues (ATOM records):
    >6x78H (H:)
qvqlqqpgaefvkpgasvrmsckasgytftsywiawvkqrpgqglewigdiypgsgytny
ngklknratltvdtssntaymqlssltsedsavyyctrggttfvaepwlaywgqgtlvav
saasttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlq
sdlytlsssvtvpsstwpsetvtcnvahpasstkvdkkivprd

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6x78I (I:)
avglgavf

    Sequence, based on observed residues (ATOM records):
    >6x78I (I:)
avglg

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6x78L (L:)
dvvmtqtaltlsvtigqpasisckssqslldsdgktylnwllqrpgqspkrliylvskld
sgvpdrftgsgsgtdftlkisrveaedlgvyycwqgthfpqtfgggtrleikrtdaaptv
sifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysm
sstltltkdeyerhnsytceathktstspivksfnrnec

    Sequence, based on observed residues (ATOM records):
    >6x78L (L:)
dvvmtqtaltlsvtigqpasisckssqslldsdgktylnwllqrpgqspkrliylvskld
sgvpdrftgsgsgtdftlkisrveaedlgvyycwqgthfpqtfgggtrleikrtdaaptv
sifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysm
sstltltkdeyerhnsytceathktstspivksfnrne