PDB entry 6x5e

View 6x5e on RCSB PDB site
Description: Crystal structure of a Lewis-binding Fab (ch88.2)
Class: immune system
Keywords: immunoglobulin, chimeric antibody, antigen binding fragment, Lewis-binding antibody, IMMUNE SYSTEM
Deposited on 2020-05-26, released 2020-08-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-30, with a file datestamp of 2020-09-25.
Experiment type: XRAY
Resolution: 2.29 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ch88.2 Fab light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6X5E (0-213)
    Domains in SCOPe 2.08: d6x5ea1, d6x5ea2
  • Chain 'B':
    Compound: ch88.2 Fab heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6X5E (0-226)
    Domains in SCOPe 2.08: d6x5eb_
  • Chain 'H':
    Compound: ch88.2 Fab heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6X5E (0-End)
    Domains in SCOPe 2.08: d6x5eh_
  • Chain 'L':
    Compound: ch88.2 Fab light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6X5E (0-End)
    Domains in SCOPe 2.08: d6x5el1, d6x5el2
  • Heterogens: NI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6x5eA (A:)
diqmtqsptslsasvgetvtitcrtsenihnfltwyqqkqgkspqvlvynaktlpdgvps
rfsgsgsgtqyslkinslqpedfgtyycqhfwsspwtfgggtkleikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6x5eB (B:)
evkleesggglvqpggsmklscaasgftfsdawmnwvrqspekglewvaeirskvinpai
yyaesvkerftilrddskssvylqmnslraedtgiyycsrstmittrdpsryfdvwgagt
tvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfp
avlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

    Sequence, based on observed residues (ATOM records): (download) 
    >6x5eB (B:)
evkleesggglvqpggsmklscaasgftfsdawmnwvrqspekglewvaeirskvinpai
yyaesvkerftilrddskssvylqmnslraedtgiyycsrstmittrdpsryfdvwgagt
tvtvssastkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6x5eH (H:)
evkleesggglvqpggsmklscaasgftfsdawmnwvrqspekglewvaeirskvinpai
yyaesvkerftilrddskssvylqmnslraedtgiyycsrstmittrdpsryfdvwgagt
tvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfp
avlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

    Sequence, based on observed residues (ATOM records): (download) 
    >6x5eH (H:)
evkleesggglvqpggsmklscaasgftfsdawmnwvrqspekglewvaeirskvinpai
yyaesvkerftilrddskssvylqmnslraedtgiyycsrstmittrdpsryfdvwgagt
tvtvssastkgpsvfplapgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6x5eL (L:)
diqmtqsptslsasvgetvtitcrtsenihnfltwyqqkqgkspqvlvynaktlpdgvps
rfsgsgsgtqyslkinslqpedfgtyycqhfwsspwtfgggtkleikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >6x5eL (L:)
diqmtqsptslsasvgetvtitcrtsenihnfltwyqqkqgkspqvlvynaktlpdgvps
rfsgsgsgtqyslkinslqpedfgtyycqhfwsspwtfgggtkleikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrge