PDB entry 6x4i

View 6x4i on RCSB PDB site
Description: Crystal Structure of NSP15 Endoribonuclease from SARS CoV-2 in the Complex with 3'-uridinemonophosphate
Class: viral protein
Keywords: SARS Corona virus 2, endoribonuclease, COVID-19, Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID, VIRAL PROTEIN
Deposited on 2020-05-22, released 2020-06-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-02-24, with a file datestamp of 2021-02-19.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Uridylate-specific endoribonuclease
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (24-369)
      • expression tag (22-23)
    Domains in SCOPe 2.08: d6x4ia1, d6x4ia2, d6x4ia3
  • Chain 'B':
    Compound: Uridylate-specific endoribonuclease
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (24-End)
      • expression tag (22-23)
    Domains in SCOPe 2.08: d6x4ib1, d6x4ib2, d6x4ib3
  • Heterogens: U3P, EDO, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6x4iA (A:)
mhhhhhhssgvdlgtenlyfqsnmslenvafnvvnkghfdgqqgevpvsiinntvytkvd
gvdvelfenkttlpvnvafelwakrnikpvpevkilnnlgvdiaantviwdykrdapahi
stigvcsmtdiakkpteticapltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvg
pkqaslngvtligeavktqfnyykkvdgvvqqlpetyftqsrnlqefkprsqmeidflel
amdefieryklegyafehivygdfshsqlgglhlliglakrfkespfeledfipmdstvk
nyfitdaqtgsskcvcsvidlllddfveiiksqdlsvvskvvkvtidyteisfmlwckdg
hvetfypklq

    Sequence, based on observed residues (ATOM records): (download) 
    >6x4iA (A:)
nmslenvafnvvnkghfdgqqgevpvsiinntvytkvdgvdvelfenkttlpvnvafelw
akrnikpvpevkilnnlgvdiaantviwdykrdapahistigvcsmtdiakkpteticap
ltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvgpkqaslngvtligeavktqfny
ykkvdgvvqqlpetyftqsrnlqefkprsqmeidflelamdefieryklegyafehivyg
dfshsqlgglhlliglakrfkespfeledfipmdstvknyfitdaqtgsskcvcsvidll
lddfveiiksqdlsvvskvvkvtidyteisfmlwckdghvetfypklq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6x4iB (B:)
mhhhhhhssgvdlgtenlyfqsnmslenvafnvvnkghfdgqqgevpvsiinntvytkvd
gvdvelfenkttlpvnvafelwakrnikpvpevkilnnlgvdiaantviwdykrdapahi
stigvcsmtdiakkpteticapltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvg
pkqaslngvtligeavktqfnyykkvdgvvqqlpetyftqsrnlqefkprsqmeidflel
amdefieryklegyafehivygdfshsqlgglhlliglakrfkespfeledfipmdstvk
nyfitdaqtgsskcvcsvidlllddfveiiksqdlsvvskvvkvtidyteisfmlwckdg
hvetfypklq

    Sequence, based on observed residues (ATOM records): (download) 
    >6x4iB (B:)
nmslenvafnvvnkghfdgqqgevpvsiinntvytkvdgvdvelfenkttlpvnvafelw
akrnikpvpevkilnnlgvdiaantviwdykrdapahistigvcsmtdiakkpteticap
ltvffdgrvdgqvdlfrnarngvlitegsvkglqpsvgpkqaslngvtligeavktqfny
ykkvdgvvqqlpetyftqsrnlqefkprsqmeidflelamdefieryklegyafehivyg
dfshsqlgglhlliglakrfkespfeledfipmdstvknyfitdaqtgsskcvcsvidll
lddfveiiksqdlsvvskvvkvtidyteisfmlwckdghvetfypkl