PDB entry 6x3n

View 6x3n on RCSB PDB site
Description: Co-structure of BTK kinase domain with L-005085737 inhibitor
Class: transferase
Keywords: Bruton tyrosine kinase inhibitor, TRANSFERASE
Deposited on 2020-05-21, released 2020-07-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-08-12, with a file datestamp of 2020-08-07.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase BTK
    Species: Homo sapiens [TaxId:9606]
    Gene: BTK, AGMX1, ATK, BPK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6x3na_
  • Heterogens: ULV, 5WE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6x3nA (A:)
glgygsweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefieeakv
mmnlsheklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvcea
meyleskqflhrdlaarnclvndqgvvkvsdfglsryvlddeytssvgskfpvrwsppev
lmyskfssksdiwafgvlmweiyslgkmpyerftnsetaehiaqglrlyrphlasekvyt
imyscwhekaderptfkillsnildvmdees

    Sequence, based on observed residues (ATOM records): (download) 
    >6x3nA (A:)
ygsweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefieeakvmmn
lsheklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceamey
leskqflhrdlaarnclvndqgvvkvsdfglskfpvrwsppevlmyskfssksdiwafgv
lmweiyslgkmpyerftnsetaehiaqglrlyrphlasekvytimyscwhekaderptfk
illsnildvmdees