PDB entry 6x2y
View 6x2y on RCSB PDB site
Description: Crystal Structure of mDia2NES peptide bound to CRM1(E571K)
Class: protein transport
Keywords: Nuclear export, CRM1, XPO1, Exportin-1, PROTEIN TRANSPORT
Deposited on
2020-05-21, released
2020-07-01
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-08-12, with a file datestamp of
2020-08-07.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.33
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: GTP-binding nuclear protein ran
Species: Homo sapiens [TaxId:9606]
Gene: RAN, ARA24, OK/SW-cl.81
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6x2ya_ - Chain 'B':
Compound: Ran-specific GTPase-activating protein 1
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: YRB1, CST20, HTN1, SFO1, YDR002W, YD8119.08
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6x2yb_ - Chain 'C':
Compound: Exportin-1
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: CRM1, KAP124, XPO1, YGR218W, G8514
Database cross-references and differences (RAF-indexed):
- Uniprot P30822 (3-End)
- expression tag (2)
- conflict (502)
- conflict (504-506)
- engineered mutation (547)
- conflict (987)
- Chain 'D':
Compound: Protein diaphanous homolog 3
Species: Homo sapiens [TaxId:9606]
Gene: DIAPH3, DIAP3
Database cross-references and differences (RAF-indexed):
- Heterogens: GNP, MG, GOL, EDO, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6x2yA (A:)
maaqgepqvqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpik
fnvwdtagqekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlc
gnkvdikdrkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlefvamp
alappevvmdpalaaqyehdlevaqttalpdedddl
Sequence, based on observed residues (ATOM records): (download)
>6x2yA (A:)
vqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpikfnvwdtag
qekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkvdikd
rkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlefvampalappedp
alaaqyehdlevaqttalpdedddl
- Chain 'B':
Sequence, based on SEQRES records: (download)
>6x2yB (B:)
dihfepvvhlekvdvktmeedeevlykvraklfrfdadakewkergtgdckflknkktnk
vrilmrrdktlkicanhiiapeytlkpnvgsdrswvyactadiaegeaeaftfairfgsk
enadkfkeefekaqeinkka
Sequence, based on observed residues (ATOM records): (download)
>6x2yB (B:)
tmeedeevlykvraklfrfdadakewkergtgdckflknkktnkvrilmrrdktlkican
hiiapeytlkpnvgsdrswvyactadiaegeaeaftfairfgskenadkfkeefekaqei
nkk
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.