SCOPe 2.08: Structural Classification of Proteins

PDB entry 6x2j

View 6x2j on RCSB PDB site
Description: structure of human trpa1 in complex with agonist gne551
Deposited on 2020-05-20, released 2020-11-18
The last revision was dated 2021-02-03, with a file datestamp of 2021-01-29.
Experiment type: EM
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Transient receptor potential cation channel subfamily A member 1
Species: Homo sapiens [TaxId:9606]
Gene: TRPA1, ANKTM1
Database cross-references and differences (RAF-indexed):
- Uniprot O75762 (0-630)
  - conflict (518)
Chain 'B':
Compound: Transient receptor potential cation channel subfamily A member 1
Species: Homo sapiens [TaxId:9606]
Gene: TRPA1, ANKTM1
Database cross-references and differences (RAF-indexed):
- Uniprot O75762 (0-630)
  - conflict (518)
Chain 'C':
Compound: Transient receptor potential cation channel subfamily A member 1
Species: Homo sapiens [TaxId:9606]
Gene: TRPA1, ANKTM1
Database cross-references and differences (RAF-indexed):
- Uniprot O75762 (0-630)
  - conflict (518)
Chain 'D':
Compound: Transient receptor potential cation channel subfamily A member 1
Species: Homo sapiens [TaxId:9606]
Gene: TRPA1, ANKTM1
Database cross-references and differences (RAF-indexed):
- Uniprot O75762 (0-630)
  - conflict (518)
Heterogens: ULJ

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

Chain 'A':
Sequence, based on SEQRES records:

>6x2jA (A:)
splhfaasygrintcqrllqdisdtrllnegdlhgmtplhlaaknghdkvvqlllkkgal
flsdhngwtalhhasmggytqtmkvildtnlkctdrldedgntalhfaareghakavall
lshnadivlnkqqasflhlalhnkrkevvltiirskrwdeclkifshnspgnkcpitemi
eylpecmkvlldfcmlhstedkscrdyyieynfkylqcpleftkktptqdviyepltaln
amvqnnriellnhpvckeyllmkwlaygfrahmmnlgsyclglipmtilvvnikpgmafn
stgiinetsdhseildttnsyliktcmilvflssifgyckeagqifqqkrnyfmdisnvl
ewiiyttgiifvlplfveipahlqwqcgaiavyfywmnfllylqrfencgifivmlevil
ktllrstvvfiflllafglsfyillnlqdpfsspllsiiqtfsmmlgdinyresflepyl
rnelahpvlsfaqlvsftifvpivlmnlliglavgdiadvqkhaslkriamqvelhtsle
kklplwflrkvdqkstivypnkprsggmlfhifcflfctgeirqeipnadkslemeilkq
kyrlkdltfllekqhelikliiqkmeiiset

Sequence, based on observed residues (ATOM records):

>6x2jA (A:)
splhfaasygrintcqrllqdisdtrllnegdlhgmtplhlaaknghdkvvqlllkkgal
flsdhngwtalhhasmggytqtmkvildtnlkctdrldedgntalhfaareghakavall
lshnadivlnkqqasflhlalhnkrkevvltiirskrwdeclkifshnspgnkcpitemi
eylpecmkvlldfcmlhstedkscrdyyieynfkylqcltalnamvqnnriellnhpvck
eyllmkwlaygfrahmmnlgsyclglipmtilvvnikpgmafnstgiinnsyliktcmil
vflssifgyckeisnvlewiiyttgiifvlplfveipahlqwqcgaiavyfywmnfllyl
qrfencgifivmlevilktllrstvvfiflllafglsfyillnlqdpfsspllsiiqtfs
mmlgdinyresflepylrnelahpvlsfaqlvsftifvpivlmnlliglavgdiadvqkh
aslkriamqvelhtslekklplwflrkvdqkstivypslemeilkqkyrlkdltfllekq
helikliiqkmeiiset

Chain 'B':
Sequence, based on SEQRES records:

>6x2jB (B:)
splhfaasygrintcqrllqdisdtrllnegdlhgmtplhlaaknghdkvvqlllkkgal
flsdhngwtalhhasmggytqtmkvildtnlkctdrldedgntalhfaareghakavall
lshnadivlnkqqasflhlalhnkrkevvltiirskrwdeclkifshnspgnkcpitemi
eylpecmkvlldfcmlhstedkscrdyyieynfkylqcpleftkktptqdviyepltaln
amvqnnriellnhpvckeyllmkwlaygfrahmmnlgsyclglipmtilvvnikpgmafn
stgiinetsdhseildttnsyliktcmilvflssifgyckeagqifqqkrnyfmdisnvl
ewiiyttgiifvlplfveipahlqwqcgaiavyfywmnfllylqrfencgifivmlevil
ktllrstvvfiflllafglsfyillnlqdpfsspllsiiqtfsmmlgdinyresflepyl
rnelahpvlsfaqlvsftifvpivlmnlliglavgdiadvqkhaslkriamqvelhtsle
kklplwflrkvdqkstivypnkprsggmlfhifcflfctgeirqeipnadkslemeilkq
kyrlkdltfllekqhelikliiqkmeiiset

Sequence, based on observed residues (ATOM records):

>6x2jB (B:)
splhfaasygrintcqrllqdisdtrllnegdlhgmtplhlaaknghdkvvqlllkkgal
flsdhngwtalhhasmggytqtmkvildtnlkctdrldedgntalhfaareghakavall
lshnadivlnkqqasflhlalhnkrkevvltiirskrwdeclkifshnspgnkcpitemi
eylpecmkvlldfcmlhstedkscrdyyieynfkylqcltalnamvqnnriellnhpvck
eyllmkwlaygfrahmmnlgsyclglipmtilvvnikpgmafnstgiinnsyliktcmil
vflssifgyckeisnvlewiiyttgiifvlplfveipahlqwqcgaiavyfywmnfllyl
qrfencgifivmlevilktllrstvvfiflllafglsfyillnlqdpfsspllsiiqtfs
mmlgdinyresflepylrnelahpvlsfaqlvsftifvpivlmnlliglavgdiadvqkh
aslkriamqvelhtslekklplwflrkvdqkstivypslemeilkqkyrlkdltfllekq
helikliiqkmeiiset

Chain 'C':
Sequence, based on SEQRES records:

>6x2jC (C:)
splhfaasygrintcqrllqdisdtrllnegdlhgmtplhlaaknghdkvvqlllkkgal
flsdhngwtalhhasmggytqtmkvildtnlkctdrldedgntalhfaareghakavall
lshnadivlnkqqasflhlalhnkrkevvltiirskrwdeclkifshnspgnkcpitemi
eylpecmkvlldfcmlhstedkscrdyyieynfkylqcpleftkktptqdviyepltaln
amvqnnriellnhpvckeyllmkwlaygfrahmmnlgsyclglipmtilvvnikpgmafn
stgiinetsdhseildttnsyliktcmilvflssifgyckeagqifqqkrnyfmdisnvl
ewiiyttgiifvlplfveipahlqwqcgaiavyfywmnfllylqrfencgifivmlevil
ktllrstvvfiflllafglsfyillnlqdpfsspllsiiqtfsmmlgdinyresflepyl
rnelahpvlsfaqlvsftifvpivlmnlliglavgdiadvqkhaslkriamqvelhtsle
kklplwflrkvdqkstivypnkprsggmlfhifcflfctgeirqeipnadkslemeilkq
kyrlkdltfllekqhelikliiqkmeiiset

Sequence, based on observed residues (ATOM records):

>6x2jC (C:)
splhfaasygrintcqrllqdisdtrllnegdlhgmtplhlaaknghdkvvqlllkkgal
flsdhngwtalhhasmggytqtmkvildtnlkctdrldedgntalhfaareghakavall
lshnadivlnkqqasflhlalhnkrkevvltiirskrwdeclkifshnspgnkcpitemi
eylpecmkvlldfcmlhstedkscrdyyieynfkylqcltalnamvqnnriellnhpvck
eyllmkwlaygfrahmmnlgsyclglipmtilvvnikpgmafnstgiinnsyliktcmil
vflssifgyckeisnvlewiiyttgiifvlplfveipahlqwqcgaiavyfywmnfllyl
qrfencgifivmlevilktllrstvvfiflllafglsfyillnlqdpfsspllsiiqtfs
mmlgdinyresflepylrnelahpvlsfaqlvsftifvpivlmnlliglavgdiadvqkh
aslkriamqvelhtslekklplwflrkvdqkstivypslemeilkqkyrlkdltfllekq
helikliiqkmeiiset

Chain 'D':
Sequence, based on SEQRES records:

>6x2jD (D:)
splhfaasygrintcqrllqdisdtrllnegdlhgmtplhlaaknghdkvvqlllkkgal
flsdhngwtalhhasmggytqtmkvildtnlkctdrldedgntalhfaareghakavall
lshnadivlnkqqasflhlalhnkrkevvltiirskrwdeclkifshnspgnkcpitemi
eylpecmkvlldfcmlhstedkscrdyyieynfkylqcpleftkktptqdviyepltaln
amvqnnriellnhpvckeyllmkwlaygfrahmmnlgsyclglipmtilvvnikpgmafn
stgiinetsdhseildttnsyliktcmilvflssifgyckeagqifqqkrnyfmdisnvl
ewiiyttgiifvlplfveipahlqwqcgaiavyfywmnfllylqrfencgifivmlevil
ktllrstvvfiflllafglsfyillnlqdpfsspllsiiqtfsmmlgdinyresflepyl
rnelahpvlsfaqlvsftifvpivlmnlliglavgdiadvqkhaslkriamqvelhtsle
kklplwflrkvdqkstivypnkprsggmlfhifcflfctgeirqeipnadkslemeilkq
kyrlkdltfllekqhelikliiqkmeiiset

Sequence, based on observed residues (ATOM records):

>6x2jD (D:)
splhfaasygrintcqrllqdisdtrllnegdlhgmtplhlaaknghdkvvqlllkkgal
flsdhngwtalhhasmggytqtmkvildtnlkctdrldedgntalhfaareghakavall
lshnadivlnkqqasflhlalhnkrkevvltiirskrwdeclkifshnspgnkcpitemi
eylpecmkvlldfcmlhstedkscrdyyieynfkylqcltalnamvqnnriellnhpvck
eyllmkwlaygfrahmmnlgsyclglipmtilvvnikpgmafnstgiinnsyliktcmil
vflssifgyckeisnvlewiiyttgiifvlplfveipahlqwqcgaiavyfywmnfllyl
qrfencgifivmlevilktllrstvvfiflllafglsfyillnlqdpfsspllsiiqtfs
mmlgdinyresflepylrnelahpvlsfaqlvsftifvpivlmnlliglavgdiadvqkh
aslkriamqvelhtslekklplwflrkvdqkstivypslemeilkqkyrlkdltfllekq
helikliiqkmeiiset