PDB entry 6wzm

View 6wzm on RCSB PDB site
Description: LY3041658 Fab bound to CXCL8
Class: immune system
Keywords: CXCR1, CXCR2, neutrophil, interleukin-8, IMMUNE SYSTEM
Deposited on 2020-05-14, released 2020-11-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-11-25, with a file datestamp of 2020-11-20.
Experiment type: XRAY
Resolution: 2.28 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: LY3041658 Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6WZM (0-223)
    Domains in SCOPe 2.08: d6wzma_
  • Chain 'B':
    Compound: LY3041658 Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6WZM (0-End)
    Domains in SCOPe 2.08: d6wzmb1, d6wzmb2
  • Chain 'C':
    Compound: LY3041658 Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6WZM (0-223)
    Domains in SCOPe 2.08: d6wzmc_
  • Chain 'D':
    Compound: LY3041658 Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6WZM (0-End)
    Domains in SCOPe 2.08: d6wzmd1, d6wzmd2
  • Chain 'E':
    Compound: interleukin-8
    Species: Homo sapiens [TaxId:9606]
    Gene: CXCL8, IL8
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6wzme_
  • Chain 'F':
    Compound: interleukin-8
    Species: Homo sapiens [TaxId:9606]
    Gene: CXCL8, IL8
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6wzmf_
  • Heterogens: EDO, PG4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6wzmA (A:)
qvqlvqsgaevkkpgasvkvsckasgyeftsywihwvrqapgqglewmgnispnsgsany
nekfksrvtmtrdtststvymelsslrsedtavyycaregpysyypsreyygsdlwgqgt
lvtvssastkgpsvfplapcsrstsestaalgclvkdyfpepvtvswnsgaltsgvhtfp
avlqssglyslssvvtvpssslgtktytcnvdhkpsntkvdkrv

    Sequence, based on observed residues (ATOM records): (download) 
    >6wzmA (A:)
qvqlvqsgaevkkpgasvkvsckasgyeftsywihwvrqapgqglewmgnispnsgsany
nekfksrvtmtrdtststvymelsslrsedtavyycaregpysyypsreyygsdlwgqgt
lvtvssastkgpsvfplapcsrsestaalgclvkdyfpepvtvswnsgaltsgvhtfpav
lqssglyslssvvtvpssslgtktytcnvdhkpsntkvdkrv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6wzmB (B:)
eivltqspatlslspgeratlscrasqsisnnlhwyqqkpgqaprlliyytsrsvsgipa
rfsgsgsgtdftltisslepedfavyycgqnnewpevfgggtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >6wzmB (B:)
eivltqspatlslspgeratlscrasqsisnnlhwyqqkpgqaprlliyytsrsvsgipa
rfsgsgsgtdftltisslepedfavyycgqnnewpevfgggtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrge

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6wzmC (C:)
qvqlvqsgaevkkpgasvkvsckasgyeftsywihwvrqapgqglewmgnispnsgsany
nekfksrvtmtrdtststvymelsslrsedtavyycaregpysyypsreyygsdlwgqgt
lvtvssastkgpsvfplapcsrstsestaalgclvkdyfpepvtvswnsgaltsgvhtfp
avlqssglyslssvvtvpssslgtktytcnvdhkpsntkvdkrv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6wzmD (D:)
eivltqspatlslspgeratlscrasqsisnnlhwyqqkpgqaprlliyytsrsvsgipa
rfsgsgsgtdftltisslepedfavyycgqnnewpevfgggtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >6wzmD (D:)
eivltqspatlslspgeratlscrasqsisnnlhwyqqkpgqaprlliyytsrsvsgipa
rfsgsgsgtdftltisslepedfavyycgqnnewpevfgggtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrge

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6wzmE (E:)
sakelrcqciktyskpfhpkfikelrviesgphcanteiivklsdgrelcldpkenwvqr
vvekfl

    Sequence, based on observed residues (ATOM records): (download) 
    >6wzmE (E:)
kelrcqciktyskpfhpkfikelrviesgphcanteiivklsdgrelcldpkenwvqrvv
ekfl

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6wzmF (F:)
sakelrcqciktyskpfhpkfikelrviesgphcanteiivklsdgrelcldpkenwvqr
vvekfl

    Sequence, based on observed residues (ATOM records): (download) 
    >6wzmF (F:)
akelrcqciktyskpfhpkfikelrviesgphcanteiivklsdgrelcldpkenwvqrv
vekfl