PDB entry 6wyr

View 6wyr on RCSB PDB site
Description: Crystal structure of anti-Muscle Specific Kinase (MuSK) Fab, MuSK1A
Class: immune system
Keywords: Human Fab, anti-MuSK, IMMUNE SYSTEM
Deposited on 2020-05-13, released 2020-07-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-02, with a file datestamp of 2020-08-28.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: MuSK1A heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6WYR (0-End)
    Domains in SCOPe 2.08: d6wyrh_
  • Chain 'I':
    Compound: MuSK1A heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6WYR (0-End)
    Domains in SCOPe 2.08: d6wyri_
  • Chain 'L':
    Compound: MuSK1A light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6WYR (Start-213)
    Domains in SCOPe 2.08: d6wyrl1, d6wyrl2
  • Chain 'M':
    Compound: MuSK1A light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6WYR (Start-213)
    Domains in SCOPe 2.08: d6wyrm1, d6wyrm2
  • Heterogens: EDO, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6wyrH (H:)
evqlvqsgaevkkpgasvkvscktsgytfnnydinwvrqaagqglewmgwmnpysgntgy
aqkfqgrvtmtrnisittvymelsslrsedtavyycarevrgdtgygggsdywgqgtlvt
vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkschhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6wyrH (H:)
evqlvqsgaevkkpgasvkvscktsgytfnnydinwvrqaagqglewmgwmnpysgntgy
aqkfqgrvtmtrnisittvymelsslrsedtavyycarevrgygggsdywgqgtlvtvss
astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepks

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >6wyrI (I:)
evqlvqsgaevkkpgasvkvscktsgytfnnydinwvrqaagqglewmgwmnpysgntgy
aqkfqgrvtmtrnisittvymelsslrsedtavyycarevrgdtgygggsdywgqgtlvt
vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkschhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6wyrI (I:)
evqlvqsgaevkkpgasvkvscktsgytfnnydinwvrqaagqglewmgwmnpysgntgy
aqkfqgrvtmtrnisittvymelsslrsedtavyycarevrgdtgygggsdywgqgtlvt
vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepksc

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6wyrL (L:)
syeltqppsvslspgqtatitcsgdklddnyvcwyqqkpgqspvlviyqdtmrpsgiper
fsgsnsgniatltisgtqavdeadyycqawdgstvvfgggtrltvlgqpkaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >6wyrL (L:)
yeltqppsvslspgqtatitcsgdklddnyvcwyqqkpgqspvlviyqdtmrpsgiperf
sgsnsgniatltisgtqavdeadyycqawdgstvvfgggtrltvlgqpkaapsvfifpps
deqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltl
skadyekhkvyacevthqglsspvtksfnrgec

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >6wyrM (M:)
syeltqppsvslspgqtatitcsgdklddnyvcwyqqkpgqspvlviyqdtmrpsgiper
fsgsnsgniatltisgtqavdeadyycqawdgstvvfgggtrltvlgqpkaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >6wyrM (M:)
eltqppsvslspgqtatitcsgdklddnyvcwyqqkpgqspvlviyqdtmrpsgiperfs
gsnsgniatltisgtqavdeadyycqawdgstvvfgggtrltvlgqpkaapsvfifppsd
eqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltls
kadyekhkvyacevthqglsspvtksfnrgec