PDB entry 6wx9

View 6wx9 on RCSB PDB site
Description: SOX2 bound to Importin-alpha 5
Class: nuclear protein
Keywords: Importin, SOX2, NUCLEAR PROTEIN
Deposited on 2020-05-10, released 2020-10-28
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-10-28, with a file datestamp of 2020-10-23.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Importin subunit alpha-5
    Species: Homo sapiens [TaxId:9606]
    Gene: KPNA1, RCH2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6wx9a_
  • Chain 'B':
    Compound: transcription factor sox-2
    Species: Homo sapiens [TaxId:9606]
    Gene: SOX2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6wx9A (A:)
ssnmemapggvitsdmiemifskspeqqlsatqkfrkllskepnppidevistpgvvarf
veflkrkenctlqfesawvltniasgnslqtriviqagavpifiellssefedvqeqavw
algniagdstmcrdyvldcnilppllqlfskqnrltmtrnavwalsnlcrgkspppefak
vspclnvlswllfvsdtdvladacwalsylsdgpndkiqavidagvcrrlvellmhndyk
vvspalravgnivtgddiqtqvilncsalqsllhllsspkesikkeacwtisnitagnra
qiqtvidanifpalisilqtaefrtrkeaawaitnatsggsaeqikylvelgcikplcdl
ltvmdskivqvalnglenilrlgeqeakrngtginpycalieeaygldkieflqshenqe
iyqkafdliehyfgtededssiapqvdlnqqqyifqqceapmegfql

    Sequence, based on observed residues (ATOM records): (download) 
    >6wx9A (A:)
gvitsdmiemifskspeqqlsatqkfrkllskepnppidevistpgvvarfveflkrken
ctlqfesawvltniasgnslqtriviqagavpifiellssefedvqeqavwalgniagds
tmcrdyvldcnilppllqlfskqnrltmtrnavwalsnlcrgkspppefakvspclnvls
wllfvsdtdvladacwalsylsdgpndkiqavidagvcrrlvellmhndykvvspalrav
gnivtgddiqtqvilncsalqsllhllsspkesikkeacwtisnitagnraqiqtvidan
ifpalisilqtaefrtrkeaawaitnatsggsaeqikylvelgcikplcdlltvmdskiv
qvalnglenilrlgeqeakrngtginpycalieeaygldkieflqshenqeiyqkafdli
ehyf

  • Chain 'B':
    No sequence available.