PDB entry 6wx7

View 6wx7 on RCSB PDB site
Description: SOX2 bound to Importin-alpha 2
Class: nuclear protein
Keywords: nuclear protein
Deposited on 2020-05-09, released 2020-10-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-01-20, with a file datestamp of 2021-01-15.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Importin subunit alpha-1
    Species: Mus musculus [TaxId:10090]
    Gene: Kpna2, Rch1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6wx7a_
  • Chain 'B':
    Compound: transcription factor sox-2
    Species: Homo sapiens [TaxId:9606]
    Gene: SOX2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6wx7A (A:)
mhhhhhhssglvprgsgmletaaalfernhmdspdlgtddddlamadigsnqgtvnwsve
divkginsnnlesqlqatqaarkllsrekqppidniiraglipkfvsflgktdcspiqfe
sawaltniasgtseqtkavvdggaipafisllasphahiseqavwalgniagdgsafrdl
vikhgaidpllallavpdlstlacgylrnltwtlsnlcrnknpappldaveqilptlvrl
lhhndpevladscwaisyltdgpneriemvvkkgvvpqlvkllgatelpivtpalraign
ivtgtdeqtqkvidagalavfpslltnpktniqkeatwtmsnitagrqdqiqqvvnhglv
pflvgvlskadfktqkeaawaitnytsggtveqivylvhcgiieplmnllsakdtkiiqv
ildaisnifqaaeklgeteklsimieecggldkiealqrhenesvykaslnliekyfsve
eeedqnvvpettsegfafqvqdgapgtfnf

    Sequence, based on observed residues (ATOM records): (download) 
    >6wx7A (A:)
gtvnwsvedivkginsnnlesqlqatqaarkllsrekqppidniiraglipkfvsflgkt
dcspiqfesawaltniasgtseqtkavvdggaipafisllasphahiseqavwalgniag
dgsafrdlvikhgaidpllallavpdlstlacgylrnltwtlsnlcrnknpappldaveq
ilptlvrllhhndpevladscwaisyltdgpneriemvvkkgvvpqlvkllgatelpivt
palraignivtgtdeqtqkvidagalavfpslltnpktniqkeatwtmsnitagrqdqiq
qvvnhglvpflvgvlskadfktqkeaawaitnytsggtveqivylvhcgiieplmnllsa
kdtkiiqvildaisnifqaaeklgeteklsimieecggldkiealqrhenesvykaslnl
iekyfs

  • Chain 'B':
    No sequence available.