PDB entry 6wx2

View 6wx2 on RCSB PDB site
Description: vaccine-elicited mouse fp-targeting neutralizing antibody vfp16.02 with f60p mutation on light chain in complex with hiv fusion peptide (residue 512-519)
Deposited on 2020-05-09, released 2021-03-17
The last revision was dated 2021-03-17, with a file datestamp of 2021-03-12.
Experiment type: XRAY
Resolution: 2.39 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: vFP16.02 antibody heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6WX2 (0-216)
  • Chain 'B':
    Compound: vFP16.02 antibody light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6WX2 (0-217)
  • Chain 'C':
    Compound: fusion peptide
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • PDB 6WX2 (0-7)
  • Chain 'F':
    Compound: fusion peptide
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • PDB 6WX2 (0-7)
  • Chain 'H':
    Compound: vFP16.02 antibody heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6WX2 (0-216)
  • Chain 'L':
    Compound: vFP16.02 antibody light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6WX2 (0-217)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6wx2A (A:)
qvqllqsgaelvrpgasvtlsckasgyafsdyeihwvkqtpvrgldwigafdpksgasas
nqkvkgrailtadkssstaymelrsltsedsavyyctrlryfgyfdvwgtgttvtvssas
ttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdly
tlsssvtvpsstwpsetvtcnvahpasstkvdkkivp

    Sequence, based on observed residues (ATOM records):
    >6wx2A (A:)
qvqllqsgaelvrpgasvtlsckasgyafsdyeihwvkqtpvrgldwigafdpksgasas
nqkvkgrailtadkssstaymelrsltsedsavyyctrlryfgyfdvwgtgttvtvssas
ttppsvyplapsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlytlsssvt
vpsstwpsetvtcnvahpasstkvdkkivp

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >6wx2B (B:)
dvlmtqtplslpvslggqasiscrssqsvvysdgdtylewylqkpgqspklliykvsrrp
sgvpdrfsgsgsgtdftlkisrvetedlgvyycfqgshvpytfgggtkleikrtdaaptv
sifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysm
sstltltkdeyerhnsytceathktstspivksfnrne

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >6wx2C (C:)
avgigavf

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records:
    >6wx2F (F:)
avgigavf

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6wx2H (H:)
qvqllqsgaelvrpgasvtlsckasgyafsdyeihwvkqtpvrgldwigafdpksgasas
nqkvkgrailtadkssstaymelrsltsedsavyyctrlryfgyfdvwgtgttvtvssas
ttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdly
tlsssvtvpsstwpsetvtcnvahpasstkvdkkivp

    Sequence, based on observed residues (ATOM records):
    >6wx2H (H:)
qvqllqsgaelvrpgasvtlsckasgyafsdyeihwvkqtpvrgldwigafdpksgasas
nqkvkgrailtadkssstaymelrsltsedsavyyctrlryfgyfdvwgtgttvtvssas
ttppsvyplapsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlytlsssvt
vpsstwpsetvtcnvahpasstkvdkkivp

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records:
    >6wx2L (L:)
dvlmtqtplslpvslggqasiscrssqsvvysdgdtylewylqkpgqspklliykvsrrp
sgvpdrfsgsgsgtdftlkisrvetedlgvyycfqgshvpytfgggtkleikrtdaaptv
sifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysm
sstltltkdeyerhnsytceathktstspivksfnrne