PDB entry 6wwa

View 6wwa on RCSB PDB site
Description: crystal structure of human shld2-shld3-rev7 complex
Deposited on 2020-05-08, released 2021-03-03
The last revision was dated 2021-03-03, with a file datestamp of 2021-02-26.
Experiment type: XRAY
Resolution: 3.8 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitotic spindle assembly checkpoint protein MAD2B
    Species: Homo sapiens [TaxId:9606]
    Gene: Mad2l2, Mad2b, Rev7
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Mitotic spindle assembly checkpoint protein MAD2B
    Species: Homo sapiens [TaxId:9606]
    Gene: Mad2l2, Mad2b, Rev7
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Mitotic spindle assembly checkpoint protein MAD2B
    Species: Homo sapiens [TaxId:9606]
    Gene: Mad2l2, Mad2b, Rev7
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Mitotic spindle assembly checkpoint protein MAD2B
    Species: Homo sapiens [TaxId:9606]
    Gene: Mad2l2, Mad2b, Rev7
    Database cross-references and differences (RAF-indexed):
  • Chain 'X':
    Compound: Shieldin complex subunit 2,Shieldin complex subunit 3 chimera
    Species: Homo sapiens [TaxId:9606]
    Gene: SHLD3, FLJ26957, RINN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q86V20 (1-End)
    • Uniprot Q6ZNX1 (32-88)
      • expression tag (89-90)
  • Chain 'Y':
    Compound: Shieldin complex subunit 2,Shieldin complex subunit 3 chimera
    Species: Homo sapiens [TaxId:9606]
    Gene: SHLD3, FLJ26957, RINN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q86V20 (1-End)
    • Uniprot Q6ZNX1 (32-88)
      • expression tag (89-91)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6wwaA (A:)
    sttltrqdlnfgqvvadvlceflevavhlilyvrevypvgifqkrkkynvpvqmschpel
    nqyiqdtlhcvkpllekndvekvvvvildkehrpvekfvfeitqppllsissdsllshve
    qllrafilkisvcdavldhnppgctftvlvhtreaatrnmekiqvikdfpwiladeqdvh
    mhdprliplktmtsdilkmqlyveerahkgs
    

    Sequence, based on observed residues (ATOM records):
    >6wwaA (A:)
    gqvvadvlceflevavhlilyvrevypvgifqkrkkynvpvqmschpelnqyiqdtlhcv
    kpllekndvekvvvvildkehrpvekfvfeitqppllsllshveqllrafilkisvcdav
    ldhnppgctftvlvhtreaatrnmekiqvikdfpwiladeqdvhmhdprliplktmtsdi
    lkmqlyveerah
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6wwaB (B:)
    sttltrqdlnfgqvvadvlceflevavhlilyvrevypvgifqkrkkynvpvqmschpel
    nqyiqdtlhcvkpllekndvekvvvvildkehrpvekfvfeitqppllsissdsllshve
    qllrafilkisvcdavldhnppgctftvlvhtreaatrnmekiqvikdfpwiladeqdvh
    mhdprliplktmtsdilkmqlyveerahkgs
    

    Sequence, based on observed residues (ATOM records):
    >6wwaB (B:)
    gqvvadvlceflevavhlilyvrevypvgifqkrkkynvpvqmschpelnqyiqdtlhcv
    kpllekndvekvvvvildkehrpvekfvfeitqppllshveqllrafilkisvcdavldh
    nppgctftvlvhtreaatrmqlyveerah
    

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6wwaC (C:)
    sttltrqdlnfgqvvadvlceflevavhlilyvrevypvgifqkrkkynvpvqmschpel
    nqyiqdtlhcvkpllekndvekvvvvildkehrpvekfvfeitqppllsissdsllshve
    qllrafilkisvcdavldhnppgctftvlvhtreaatrnmekiqvikdfpwiladeqdvh
    mhdprliplktmtsdilkmqlyveerahkgs
    

    Sequence, based on observed residues (ATOM records):
    >6wwaC (C:)
    gqvvadvlceflevavhlilyvrevypvgifqkrkkynvpvqmschpelnqyiqdtlhcv
    kpllekndvekvvvvildkehrpvekfvfeitqppssdsllshveqllrafilkisvcda
    vldhnppgctftvlvhtrktmtsdilkmqlyveerah
    

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6wwaD (D:)
    sttltrqdlnfgqvvadvlceflevavhlilyvrevypvgifqkrkkynvpvqmschpel
    nqyiqdtlhcvkpllekndvekvvvvildkehrpvekfvfeitqppllsissdsllshve
    qllrafilkisvcdavldhnppgctftvlvhtreaatrnmekiqvikdfpwiladeqdvh
    mhdprliplktmtsdilkmqlyveerahkgs
    

    Sequence, based on observed residues (ATOM records):
    >6wwaD (D:)
    gqvvadvlceflevavhlilyvrevypvgifqkrkkynvpvqmschpelnqyiqdtlhcv
    kpllekndvekvvvvildkehrpvekfvfeitqppllsllshveqllrafilkisvcdav
    ldhnppgctftvlvhtreaatrnmekiqvikdfpwiladeqdvhmhdprliplktmtsdi
    lkmqlyveerah
    

  • Chain 'X':
    Sequence, based on SEQRES records:
    >6wwaX (X:)
    msqvhifwgapiaplkgsgsgsgsgsgsgsgsttevilhyrpcesdptqlpkiaekaiqd
    fptrplsrfipwfpydgsklplrpkrsppasreeimatl
    

    Sequence, based on observed residues (ATOM records):
    >6wwaX (X:)
    sqvhifwgapiapttevilhyrpcesdptqlpkiaekaiqdfptrplsrfipwfpydgsk
    lplrpkrsppas
    

  • Chain 'Y':
    Sequence, based on SEQRES records:
    >6wwaY (Y:)
    msqvhifwgapiaplkgsgsgsgsgsgsgsgsttevilhyrpcesdptqlpkiaekaiqd
    fptrplsrfipwfpydgsklplrpkrsppasreeimatl
    

    Sequence, based on observed residues (ATOM records):
    >6wwaY (Y:)
    sqvhifwgapiapttevilhyrpcesdptqlpkiaekaiqdfptrplsrfipwfpydgsk
    lplrpkrsppasr