PDB entry 6ww1

View 6ww1 on RCSB PDB site
Description: Crystal structure of the LmFPPS mutant E97Y
Class: transferase
Keywords: FPPS, Farnesyl diphosphate synthase, TRANSFERASE
Deposited on 2020-05-07, released 2020-10-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-07, with a file datestamp of 2020-10-02.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: farnesyl pyrophosphate synthase
    Species: Leishmania major [TaxId:5664]
    Gene: FPPS, LMJF_22_1360
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4QBL1 (0-361)
      • engineered mutation (96)
    Domains in SCOPe 2.08: d6ww1a_
  • Chain 'B':
    Compound: farnesyl pyrophosphate synthase
    Species: Leishmania major [TaxId:5664]
    Gene: FPPS, LMJF_22_1360
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4QBL1 (0-361)
      • engineered mutation (96)
    Domains in SCOPe 2.08: d6ww1b_
  • Heterogens: 476, CA, IPR, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6ww1A (A:)
    mahmerfqkvyeevqefllgdaekrfemdvhrkgylksmmdttclggkynrglcvvdvae
    amakdtqmdaaamervlhdacvcgwmiemlqahflvyddimdhsktrrgkpcwylhpgvt
    aqvaindglillawatqmalhyfadrpflaevlrvfhdvdltttigqlydvtsmvdsakl
    dakvahanttdyveytpfnhrrivvyktayytywlplvmgllvsgtlekvdkkathkvam
    vmgeyfqvqddvmdcftppeklgkigtdiedakcswlavtflttapaekvaefkanygst
    dpaavavikqlyteqnllarfeeyekavvaeveqliaaleaqnaafaasvkvlwsktykr
    qk
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6ww1B (B:)
    mahmerfqkvyeevqefllgdaekrfemdvhrkgylksmmdttclggkynrglcvvdvae
    amakdtqmdaaamervlhdacvcgwmiemlqahflvyddimdhsktrrgkpcwylhpgvt
    aqvaindglillawatqmalhyfadrpflaevlrvfhdvdltttigqlydvtsmvdsakl
    dakvahanttdyveytpfnhrrivvyktayytywlplvmgllvsgtlekvdkkathkvam
    vmgeyfqvqddvmdcftppeklgkigtdiedakcswlavtflttapaekvaefkanygst
    dpaavavikqlyteqnllarfeeyekavvaeveqliaaleaqnaafaasvkvlwsktykr
    qk