PDB entry 6wt3

View 6wt3 on RCSB PDB site
Description: Structural basis for the binding of monoclonal antibody 5D2 to the tryptophan-rich lipid-binding loop in lipoprotein lipase
Class: immune system
Keywords: 5d2, lipoprotein lipase, immune system
Deposited on 2020-05-01, released 2020-07-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-12-02, with a file datestamp of 2020-11-27.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: 5d2 fab heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6WT3 (Start-222)
    Domains in SCOPe 2.08: d6wt3h_
  • Chain 'L':
    Compound: 5d2 fab light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6WT3
    Domains in SCOPe 2.08: d6wt3l1, d6wt3l2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6wt3H (H:)
skvqlqqsgaelvkpgasvklsckasgytfteyiihwvkqksgqglewigwfypgsgnik
ynekfkdkatltadkssstvymelsrltsedsavyfcarhedrnyysywdywgqgttltv
ssakttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlq
sdlytlsssvtvpsstwpsetvtcnvahpasstkvdkkivprd

    Sequence, based on observed residues (ATOM records): (download) 
    >6wt3H (H:)
kvqlqqsgaelvkpgasvklsckasgytfteyiihwvkqksgqglewigwfypgsgniky
nekfkdkatltadkssstvymelsrltsedsavyfcarhedrnyysywdywgqgttltvs
sakttppsvyplapgsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlytls
ssvtvpsstwpsetvtcnvahpasstkvdkkivprd

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6wt3L (L:)
gqivltqspalmsaspgekvtmtcsasssvsnmywyqqkprsspkpwiyltsnlasgvpa
rfsgsgsgtsysltissmeaedaatyycqqwssnpltfgagtklelkradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrnec

    Sequence, based on observed residues (ATOM records): (download) 
    >6wt3L (L:)
qivltqspalmsaspgekvtmtcsasssvsnmywyqqkprsspkpwiyltsnlasgvpar
fsgsgsgtsysltissmeaedaatyycqqwssnpltfgagtklelkradaaptvsifpps
seqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstltl
tkdeyerhnsytceathktstspivksfnrne