PDB entry 6wsl

View 6wsl on RCSB PDB site
Description: Cryo-EM structure of VASH1-SVBP bound to microtubules
Class: protein binding
Keywords: Microtubule, Posttranslational modification, Detyrosination, Vasohibin, PROTEIN BINDING
Deposited on 2020-05-01, released 2020-08-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-08-26, with a file datestamp of 2020-08-21.
Experiment type: EM
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tubulin alpha-1a chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TUBA1A, TUBA3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6wsla1, d6wsla2
  • Chain 'B':
    Compound: Tubulin beta-3 chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TUBB3, TUBB4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6wslb1, d6wslb2
  • Chain 'C':
    Compound: Tubulinyl-Tyr carboxypeptidase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: VASH1, KIAA1036, VASH
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Small vasohibin-binding protein
    Species: Homo sapiens [TaxId:9606]
    Gene: SVBP, CCDC23
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: tubulin alpha-1a chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TUBA1A, TUBA3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6wsle1, d6wsle2
  • Chain 'F':
    Compound: Tubulin beta-3 chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TUBB3, TUBB4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6wslf1, d6wslf2
  • Chain 'G':
    Compound: Tubulinyl-Tyr carboxypeptidase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: VASH1, KIAA1036, VASH
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Small vasohibin-binding protein
    Species: Homo sapiens [TaxId:9606]
    Gene: SVBP, CCDC23
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GTP, G2P

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6wslA (A:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsdktigggddsfntffsetgagk
hvpravfvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvld
rirkladqctglqgflvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvsta
vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssita
slrfdgalnvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepan
qmvkcdprhgkymaccllyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyqpp
tvvpggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefse
aredmaalekdyeevgvdsvegegeeegeey

    Sequence, based on observed residues (ATOM records): (download) 
    >6wslA (A:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpdsfntffsetgagkhvpravfvd
leptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvldrirkladqc
tglqgflvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvstavvepynsil
tthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssitaslrfdgaln
vdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepanqmvkcdprh
gkymaccllyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyqpptvvpggdla
kvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefsearedmaale
kdyeevgvdsv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6wslB (B:)
mreivhiqagqcgnqigakfwevisdehgidpsgnyvgdsdlqlerisvyyneasshkyv
prailvdlepgtmdsvrsgafghlfrpdnfifgqsgagnnwakghytegaelvdsvldvv
rkecencdclqgfqlthslgggtgsgmgtlliskvreeypdrimntfsvvpspkvsdtvv
epynatlsihqlventdetycidnealydicfrtlklatptygdlnhlvsatmsgvttsl
rfpgqlnadlrklavnmvpfprlhffmpgfapltargsqqyraltvpeltqqmfdaknmm
aacdprhgryltvatvfrgrmsmkevdeqmlaiqsknssyfvewipnnvkvavcdipprg
lkmsstfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
eyqqyqdataeeegemyeddeeeseaqgpk

    Sequence, based on observed residues (ATOM records): (download) 
    >6wslB (B:)
mreivhiqagqcgnqigakfwevisdehgidpsgnyvgdsdlqlerisvyyneasshkyv
prailvdlepgtmdsvrsgafghlfrpdnfifgqsgagnnwakghytegaelvdsvldvv
rkecencdclqgfqlthslgggtgsgmgtlliskvreeypdrimntfsvvpspkvsdtvv
epynatlsihqlventdetycidnealydicfrtlklatptygdlnhlvsatmsgvttsl
rfpgqlnadlrklavnmvpfprlhffmpgfapltargsqqyraltvpeltqqmfdaknmm
aacdprhgryltvatvfrgrmsmkevdeqmlaiqsknssyfvewipnnvkvavcdipprg
lkmsstfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
eyqqyqdat

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6wslE (E:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsdktigggddsfntffsetgagk
hvpravfvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvld
rirkladqctglqgflvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvsta
vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssita
slrfdgalnvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepan
qmvkcdprhgkymaccllyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyqpp
tvvpggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefse
aredmaalekdyeevgvdsvegegeeegeey

    Sequence, based on observed residues (ATOM records): (download) 
    >6wslE (E:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpdsfntffsetgagkhvpravfvd
leptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvldrirkladqc
tglqgflvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvstavvepynsil
tthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssitaslrfdgaln
vdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepanqmvkcdprh
gkymaccllyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyqpptvvpggdla
kvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefsearedmaale
kdyeevgvdsv

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6wslF (F:)
mreivhiqagqcgnqigakfwevisdehgidpsgnyvgdsdlqlerisvyyneasshkyv
prailvdlepgtmdsvrsgafghlfrpdnfifgqsgagnnwakghytegaelvdsvldvv
rkecencdclqgfqlthslgggtgsgmgtlliskvreeypdrimntfsvvpspkvsdtvv
epynatlsihqlventdetycidnealydicfrtlklatptygdlnhlvsatmsgvttsl
rfpgqlnadlrklavnmvpfprlhffmpgfapltargsqqyraltvpeltqqmfdaknmm
aacdprhgryltvatvfrgrmsmkevdeqmlaiqsknssyfvewipnnvkvavcdipprg
lkmsstfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
eyqqyqdataeeegemyeddeeeseaqgpk

    Sequence, based on observed residues (ATOM records): (download) 
    >6wslF (F:)
mreivhiqagqcgnqigakfwevisdehgidpsgnyvgdsdlqlerisvyyneasshkyv
prailvdlepgtmdsvrsgafghlfrpdnfifgqsgagnnwakghytegaelvdsvldvv
rkecencdclqgfqlthslgggtgsgmgtlliskvreeypdrimntfsvvpspkvsdtvv
epynatlsihqlventdetycidnealydicfrtlklatptygdlnhlvsatmsgvttsl
rfpgqlnadlrklavnmvpfprlhffmpgfapltargsqqyraltvpeltqqmfdaknmm
aacdprhgryltvatvfrgrmsmkevdeqmlaiqsknssyfvewipnnvkvavcdipprg
lkmsstfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
eyqqyqdat

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.