PDB entry 6wro

View 6wro on RCSB PDB site
Description: crystal structure of inositol polyphosphate 1-phosphatase inpp1 in complex gadolinium but no lithium at 3 angstrom resolution
Class: signaling protein
Keywords: inositol phosphate, neurological disease, Bipolar disorder, manic depressive illness, phosphatase, metal binding, cellular signaling, SIGNALING PROTEIN
Deposited on 2020-04-29, released 2020-11-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-14, with a file datestamp of 2021-07-09.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: inositol polyphosphate 1-phosphatase
    Species: Bos taurus [TaxId:9913]
    Gene: INPP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21327 (0-399)
      • conflict (83)
    Domains in SCOPe 2.08: d6wroa_
  • Heterogens: GD, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6wroA (A:)
    msdilqellrvsekaaniaracrqqetlfqllieekkegeknkkfavdfktladvlvqev
    ikenmenkfpglgkkifgeesneltndlgekiimrlgpteeetvallskvlngnklasea
    lakvvhqdvffsdpaldsveinipqdilgiwvdpidstyqyikgsaditpnqgifpsglq
    cvtvligvydiqtgvplmgvinqpfvsqdlhtrrwkgqcywglsylgtnihsllppvstr
    snseaqsqgtqnpssegscrfsvvistseketikgalshvcgerifraagagykslcvil
    gladiyifsedttfkwdscaahailramgggmvdlkeclernpdtgldlpqlvyhvgneg
    aagvdqwankggliayrsekqletflsrllqhlapvatht
    

    Sequence, based on observed residues (ATOM records): (download)
    >6wroA (A:)
    msdilqellrvsekaaniaracrqqetlfqlfavdfktladvlvqevikenmenkfpglg
    kkifgeesneltndlgekiimrlgpteeetvallskvlngnklasealakvvhqdvffsd
    paldsveinipqdilgiwvdpidstyqyikgsaditpnqgifpsglqcvtvligvydiqt
    gvplmgvinqpfvsqdlhtrrwkgqcywglsylgtnihsllppvvvistseketikrifr
    aagagykslcvilgladiyifsedttfkwdscaahailramgggmvdlkeclelpqlvyh
    vgnqwankggliayrsekqletflsrl