PDB entry 6wqz

View 6wqz on RCSB PDB site
Description: structure of human atg9a, the only transmembrane protein of the core autophagy machinery
Deposited on 2020-04-29, released 2020-07-08
The last revision was dated 2020-07-15, with a file datestamp of 2020-07-10.
Experiment type: EM
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Autophagy-related protein 9A
    Species: Homo sapiens [TaxId:9606]
    Gene: ATG9A, APG9L1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Autophagy-related protein 9A
    Species: Homo sapiens [TaxId:9606]
    Gene: ATG9A, APG9L1
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Autophagy-related protein 9A
    Species: Homo sapiens [TaxId:9606]
    Gene: ATG9A, APG9L1
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Autophagy-related protein 9A
    Species: Homo sapiens [TaxId:9606]
    Gene: ATG9A, APG9L1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7Z3C6
    • PDB 6WQZ (688-723)
  • Chain 'E':
    Compound: Autophagy-related protein 9A
    Species: Homo sapiens [TaxId:9606]
    Gene: ATG9A, APG9L1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7Z3C6
    • PDB 6WQZ (688-723)
  • Chain 'F':
    Compound: Autophagy-related protein 9A
    Species: Homo sapiens [TaxId:9606]
    Gene: ATG9A, APG9L1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7Z3C6
    • PDB 6WQZ (688-End)
  • Heterogens: LMN

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6wqzA (A:)
    maqfdteyqrleasysdsppgeedllvhvaegskspwhhienldlffsrvynlhqkngft
    cmligeifelmqflfvvafttflvscvdydilfankmvnhslhptepvkvtlpdaflpaq
    vcsariqengslitilviagvfwihrlikfiyniccyweihsfylhalripmsalpyctw
    qevqarivqtqkehqicihkrelteldiyhrilrfqnymvalvnksllplrfrlpglgea
    vfftrglkynfelilfwgpgslflnewslkaeykrggqrlelaqrlsnrilwigianfll
    cpliliwqilyaffsyaevlkrepgalgarcwslygrcylrhfnelehelqsrlnrgykp
    askymncflsplltllakngaffagsilavlialtiydedvlavehvlttvtllgvtvtv
    crsfipdqhmvfcpeqllrvilahihympdhwqgnahrsqtrdefaqlfqykavfileel
    lspivtplilifclrpraleiidffrnftvevvgvgdtcsfaqmdvrqhghpqwlsagqt
    easvyqqaedgktelslmhfaitnpgwqpprestaflgflkeqvqrdgaaaslaqggllp
    enalftsiqslqseseplslianvvagsscrgpplprdlqgsrhraevasalrsfsplqp
    gqaptgrahstmtgsgvdartassgssvxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
    xxxx
    

    Sequence, based on observed residues (ATOM records):
    >6wqzA (A:)
    pwhhienldlffsrvynlhqkngftcmligeifelmqflfvvafttflvscvdydilfan
    kvtlpdaflpaqvcsariqengslitilviagvfwihrlikfiyniccyweihsfylhal
    ripmsalpyctwqevqarivqtqkehqicihkrelteldiyhrilrfqnymvalvnksll
    plrfrlpglgeavfftrglkynfelilfwgpgslflnewslkaeykrggqrlelaqrlsn
    rilwigianfllcpliliwqilyaffsyaevlkrepgalgarcwslygrcylrhfneleh
    elqsrlnrgykpaskymncflsplltllakngaffagsilavlialtiydedvlavehvl
    ttvtllgvtvtvcrsfipdqhmvfcpeqllrvilahihympdhwqgnahrsqtrdefaql
    fqykavfileellspivtplilifclrpraleiidffrnftvevvgvgdtcsfaqmdvrq
    hghpqwlqteasvyqqaedgktelslmhfaitnpgwqpprestaflgflkeqvqrd
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6wqzB (B:)
    maqfdteyqrleasysdsppgeedllvhvaegskspwhhienldlffsrvynlhqkngft
    cmligeifelmqflfvvafttflvscvdydilfankmvnhslhptepvkvtlpdaflpaq
    vcsariqengslitilviagvfwihrlikfiyniccyweihsfylhalripmsalpyctw
    qevqarivqtqkehqicihkrelteldiyhrilrfqnymvalvnksllplrfrlpglgea
    vfftrglkynfelilfwgpgslflnewslkaeykrggqrlelaqrlsnrilwigianfll
    cpliliwqilyaffsyaevlkrepgalgarcwslygrcylrhfnelehelqsrlnrgykp
    askymncflsplltllakngaffagsilavlialtiydedvlavehvlttvtllgvtvtv
    crsfipdqhmvfcpeqllrvilahihympdhwqgnahrsqtrdefaqlfqykavfileel
    lspivtplilifclrpraleiidffrnftvevvgvgdtcsfaqmdvrqhghpqwlsagqt
    easvyqqaedgktelslmhfaitnpgwqpprestaflgflkeqvqrdgaaaslaqggllp
    enalftsiqslqseseplslianvvagsscrgpplprdlqgsrhraevasalrsfsplqp
    gqaptgrahstmtgsgvdartassgssvxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
    xxxx
    

    Sequence, based on observed residues (ATOM records):
    >6wqzB (B:)
    pwhhienldlffsrvynlhqkngftcmligeifelmqflfvvafttflvscvdydilfan
    kvtlpdaflpaqvcsariqengslitilviagvfwihrlikfiyniccyweihsfylhal
    ripmsalpyctwqevqarivqtqkehqicihkrelteldiyhrilrfqnymvalvnksll
    plrfrlpglgeavfftrglkynfelilfwgpgslflnewslkaeykrggqrlelaqrlsn
    rilwigianfllcpliliwqilyaffsyaevlkrepgalgarcwslygrcylrhfneleh
    elqsrlnrgykpaskymncflsplltllakngaffagsilavlialtiydedvlavehvl
    ttvtllgvtvtvcrsfipdqhmvfcpeqllrvilahihympdhwqgnahrsqtrdefaql
    fqykavfileellspivtplilifclrpraleiidffrnftvevvgvgdtcsfaqmdvrq
    hghpqwlqteasvyqqaedgktelslmhfaitnpgwqpprestaflgflkeqvqrd
    

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6wqzC (C:)
    maqfdteyqrleasysdsppgeedllvhvaegskspwhhienldlffsrvynlhqkngft
    cmligeifelmqflfvvafttflvscvdydilfankmvnhslhptepvkvtlpdaflpaq
    vcsariqengslitilviagvfwihrlikfiyniccyweihsfylhalripmsalpyctw
    qevqarivqtqkehqicihkrelteldiyhrilrfqnymvalvnksllplrfrlpglgea
    vfftrglkynfelilfwgpgslflnewslkaeykrggqrlelaqrlsnrilwigianfll
    cpliliwqilyaffsyaevlkrepgalgarcwslygrcylrhfnelehelqsrlnrgykp
    askymncflsplltllakngaffagsilavlialtiydedvlavehvlttvtllgvtvtv
    crsfipdqhmvfcpeqllrvilahihympdhwqgnahrsqtrdefaqlfqykavfileel
    lspivtplilifclrpraleiidffrnftvevvgvgdtcsfaqmdvrqhghpqwlsagqt
    easvyqqaedgktelslmhfaitnpgwqpprestaflgflkeqvqrdgaaaslaqggllp
    enalftsiqslqseseplslianvvagsscrgpplprdlqgsrhraevasalrsfsplqp
    gqaptgrahstmtgsgvdartassgssvxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
    xxxx
    

    Sequence, based on observed residues (ATOM records):
    >6wqzC (C:)
    pwhhienldlffsrvynlhqkngftcmligeifelmqflfvvafttflvscvdydilfan
    kvtlpdaflpaqvcsariqengslitilviagvfwihrlikfiyniccyweihsfylhal
    ripmsalpyctwqevqarivqtqkehqicihkrelteldiyhrilrfqnymvalvnksll
    plrfrlpglgeavfftrglkynfelilfwgpgslflnewslkaeykrggqrlelaqrlsn
    rilwigianfllcpliliwqilyaffsyaevlkrepgalgarcwslygrcylrhfneleh
    elqsrlnrgykpaskymncflsplltllakngaffagsilavlialtiydedvlavehvl
    ttvtllgvtvtvcrsfipdqhmvfcpeqllrvilahihympdhwqgnahrsqtrdefaql
    fqykavfileellspivtplilifclrpraleiidffrnftvevvgvgdtcsfaqmdvrq
    hghpqwlqteasvyqqaedgktelslmhfaitnpgwqpprestaflgflkeqvqrd
    

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6wqzD (D:)
    maqfdteyqrleasysdsppgeedllvhvaegskspwhhienldlffsrvynlhqkngft
    cmligeifelmqflfvvafttflvscvdydilfankmvnhslhptepvkvtlpdaflpaq
    vcsariqengslitilviagvfwihrlikfiyniccyweihsfylhalripmsalpyctw
    qevqarivqtqkehqicihkrelteldiyhrilrfqnymvalvnksllplrfrlpglgea
    vfftrglkynfelilfwgpgslflnewslkaeykrggqrlelaqrlsnrilwigianfll
    cpliliwqilyaffsyaevlkrepgalgarcwslygrcylrhfnelehelqsrlnrgykp
    askymncflsplltllakngaffagsilavlialtiydedvlavehvlttvtllgvtvtv
    crsfipdqhmvfcpeqllrvilahihympdhwqgnahrsqtrdefaqlfqykavfileel
    lspivtplilifclrpraleiidffrnftvevvgvgdtcsfaqmdvrqhghpqwlsagqt
    easvyqqaedgktelslmhfaitnpgwqpprestaflgflkeqvqrdgaaaslaqggllp
    enalftsiqslqseseplslianvvagsscrgpplprdlqgsrhraevasalrsfsplqp
    gqaptgrahstmtgsgvdartassgssvxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
    xxxx
    

    Sequence, based on observed residues (ATOM records):
    >6wqzD (D:)
    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
    

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6wqzE (E:)
    maqfdteyqrleasysdsppgeedllvhvaegskspwhhienldlffsrvynlhqkngft
    cmligeifelmqflfvvafttflvscvdydilfankmvnhslhptepvkvtlpdaflpaq
    vcsariqengslitilviagvfwihrlikfiyniccyweihsfylhalripmsalpyctw
    qevqarivqtqkehqicihkrelteldiyhrilrfqnymvalvnksllplrfrlpglgea
    vfftrglkynfelilfwgpgslflnewslkaeykrggqrlelaqrlsnrilwigianfll
    cpliliwqilyaffsyaevlkrepgalgarcwslygrcylrhfnelehelqsrlnrgykp
    askymncflsplltllakngaffagsilavlialtiydedvlavehvlttvtllgvtvtv
    crsfipdqhmvfcpeqllrvilahihympdhwqgnahrsqtrdefaqlfqykavfileel
    lspivtplilifclrpraleiidffrnftvevvgvgdtcsfaqmdvrqhghpqwlsagqt
    easvyqqaedgktelslmhfaitnpgwqpprestaflgflkeqvqrdgaaaslaqggllp
    enalftsiqslqseseplslianvvagsscrgpplprdlqgsrhraevasalrsfsplqp
    gqaptgrahstmtgsgvdartassgssvxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
    xxxx
    

    Sequence, based on observed residues (ATOM records):
    >6wqzE (E:)
    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
    

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6wqzF (F:)
    maqfdteyqrleasysdsppgeedllvhvaegskspwhhienldlffsrvynlhqkngft
    cmligeifelmqflfvvafttflvscvdydilfankmvnhslhptepvkvtlpdaflpaq
    vcsariqengslitilviagvfwihrlikfiyniccyweihsfylhalripmsalpyctw
    qevqarivqtqkehqicihkrelteldiyhrilrfqnymvalvnksllplrfrlpglgea
    vfftrglkynfelilfwgpgslflnewslkaeykrggqrlelaqrlsnrilwigianfll
    cpliliwqilyaffsyaevlkrepgalgarcwslygrcylrhfnelehelqsrlnrgykp
    askymncflsplltllakngaffagsilavlialtiydedvlavehvlttvtllgvtvtv
    crsfipdqhmvfcpeqllrvilahihympdhwqgnahrsqtrdefaqlfqykavfileel
    lspivtplilifclrpraleiidffrnftvevvgvgdtcsfaqmdvrqhghpqwlsagqt
    easvyqqaedgktelslmhfaitnpgwqpprestaflgflkeqvqrdgaaaslaqggllp
    enalftsiqslqseseplslianvvagsscrgpplprdlqgsrhraevasalrsfsplqp
    gqaptgrahstmtgsgvdartassgssvxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
    xxxx
    

    Sequence, based on observed residues (ATOM records):
    >6wqzF (F:)
    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx