PDB entry 6wqq

View 6wqq on RCSB PDB site
Description: structure of the 50s subunit of the ribosome from methicillin resistant staphylococcus aureus in complex with the antibiotic, radezolid
Deposited on 2020-04-29, released 2020-06-03
The last revision was dated 2020-12-16, with a file datestamp of 2020-12-11.
Experiment type: EM
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain '1':
    Compound: 23s rRNA
    Species: Staphylococcus aureus [TaxId:1280]
  • Chain '2':
    Compound: 5s rRNA
    Species: Staphylococcus aureus [TaxId:1280]
  • Chain 'A':
    Compound: 50S ribosomal protein L19
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: 50S ribosomal protein L2
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: 50S ribosomal protein L20
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: 50S ribosomal protein L21
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: 50S ribosomal protein L22
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: 50S ribosomal protein L23
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: 50S ribosomal protein L24
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: 50S ribosomal protein L25
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: 50S ribosomal protein L27
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: 50S ribosomal protein L28
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: 50S ribosomal protein L29
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: 50S ribosomal protein L3
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'M':
    Compound: 50S ribosomal protein L30
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'N':
    Compound: 50S ribosomal protein L32
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'O':
    Compound: 50S ribosomal protein L33
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: 50S ribosomal protein L34
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'Q':
    Compound: 50S ribosomal protein L35
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'R':
    Compound: 50S ribosomal protein L36
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'S':
    Compound: 50S ribosomal protein L4
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'V':
    Compound: 50S ribosomal protein L13
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'W':
    Compound: 50S ribosomal protein L14
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'X':
    Compound: 50S ribosomal protein L15
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'Y':
    Compound: 50S ribosomal protein L16
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'Z':
    Compound: 50S ribosomal protein L17
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Chain 'a':
    Compound: 50S ribosomal protein L18
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: RD8

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain '1':
    No sequence available.

  • Chain '2':
    No sequence available.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6wqqA (A:)
mtnhklieavtksqlrtdlpsfrpgdtlrvhvriiegtreriqvfegvvikrrgggvset
ftvrkissgvgvertfplhtpkiekievkrrgkvrraklyylrslrgkaariqeir

    Sequence, based on observed residues (ATOM records):
    >6wqqA (A:)
nhklieavtksqlrtdlpsfrpgdtlrvhvriiegtreriqvfegvvikrrgggvsetft
vrkissgvgvertfplhtpkiekievkrrgkvrraklyylrslrgkaariqei

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6wqqB (B:)
maikkykpitngrrnmtsldfaeitkttpeksllkplpkkagrnnqgkltvrhhggghkr
qyrvidfkrnkdginakvdsiqydpnrsanialvvyadgekryiiapkglevgqivesga
eadikvgnalplqnipvgtvvhnielkpgkggqiarsagasaqvlgkegkyvlirlrsge
vrmilstcratigqvgnlqhelvnvgkagrsrwkgirptvrgsvmnpndhphgggegrap
igrpspmspwgkptlgkktrrgkkssdklivrgrkkk

    Sequence, based on observed residues (ATOM records):
    >6wqqB (B:)
aikkykpitngrrnmtsldfaeitkttpeksllkplpkkagrnnqgkltvrhhggghkrq
yrvidfkrnkdginakvdsiqydpnrsanialvvyadgekryiiapkglevgqivesgae
adikvgnalplqnipvgtvvhnielkpgkggqiarsagasaqvlgkegkyvlirlrsgev
rmilstcratigqvgnlqhelvnvgkagrsrwkgirptvrgsvmnpndhphgggegrapi
grpspmspwgkptlgkktrrgkkssdklivrgrk

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6wqqC (C:)
mprvkggtvtrarrkktiklakgyfgskhtlykvakqqvmksgqyafrdrrqrkrdfrkl
witrinaaarqhemsysrlmnglkkagidinrkmlseiaisdekafaqlvtkakdalk

    Sequence, based on observed residues (ATOM records):
    >6wqqC (C:)
prvkggtvtrarrkktiklakgyfgskhtlykvakqqvmksgqyafrdrrqrkrdfrklw
itrinaaarqhemsysrlmnglkkagidinrkmlseiaisdekafaqlvtkakdal

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6wqqD (D:)
mqsmfaiietggkqikveegqeifvekldvnegdtftfdkvlfvggdsvkvgaptvegat
vtatvnkqgrgkkitvftykrrknskrkkghrqpytkltidkina

    Sequence, based on observed residues (ATOM records):
    >6wqqD (D:)
mfaiietggkqikveegqeifvekldvnegdtftfdkvlfvggdsvkvgaptvegatvta
tvnkqgrgkkitvftykrrknskrkkghrqpytkltidki

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6wqqE (E:)
meakavartiriaprkvrlvldlirgknaaeaiailkltnkasspviekvlmsalanaeh
nydmntdelvvkeayanegptlkrfrpraqgrasainkrtshitivvsdakeeakea

    Sequence, based on observed residues (ATOM records):
    >6wqqE (E:)
meakavartiriaprkvrlvldlirgknaaeaiailkltnkasspviekvlmsalanaeh
nydmntdelvvkeayanegptlkrfrpraqgrasainkrtshitivvsdak

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6wqqF (F:)
meardilkrpviteksseamaedkytfdvdtrvnktqvkmaveeifnvkvasvnimnykp
kkkrmgryqgytnkrrkaivtlkegsddlfn

    Sequence, based on observed residues (ATOM records):
    >6wqqF (F:)
rdilkrpviteksseamaedkytfdvdtrvnktqvkmaveeifnvkvasvnimnykpkkk
rmgryqgytnkrrkaivtlkegsddlf

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6wqqG (G:)
mhikkgdnvkviagkdkgkegkviatlpkkdrvvvegvnimkkhqkptqlnpesgilete
aaihvsnvqlldpktneptrvgykfvdgkkvriakksgeeiksnn

    Sequence, based on observed residues (ATOM records):
    >6wqqG (G:)
hikkgdnvkviagkdkgkegkviatlpkkdrvvvegvnimkkhqkptqlnpesgiletea
aihvsnvqlldpktneptrvgykfvdgkkvriakksgeei

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6wqqH (H:)
maslksiirqgkqtrsdlkqlrksgkvpavvygygtknvsvkvdevefikvirevgrngv
ielgvgsktikvmvadyqfdplknqithidflainmsedvllkyqfn

    Sequence, based on observed residues (ATOM records):
    >6wqqH (H:)
aslksiirqgkqtrsdlkqlrksgkvpavvygygtknvsvkvdevefikvirevgrngvi
elgvgsktikvmvadyqfdplknqithidflai

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6wqqI (I:)
askkgvsstkngrdseskrlgakradgqfvtggsilyrqrgtkiypgenvgrggddtlfa
kidgvvkferkgrdkkqvsvyavae

    Sequence, based on observed residues (ATOM records):
    >6wqqI (I:)
sstkngrdseskrlgakradgqfvtggsilyrqrgtkiypgenvgrggddtlfakidgvv
kferkgrdkkqvsvyava

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6wqqJ (J:)
mgkqcfvtgrkastgnrrshalnstkrrwnanlqkvrilvdgkpkkvwvsaralksgkvt
ra

    Sequence, based on observed residues (ATOM records):
    >6wqqJ (J:)
gkqcfvtgrkastgnrrshalnstkrrwnanlqkvrilvdgkpkkvwvsaralksgkvt

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6wqqK (K:)
mkkkkakeirnlttseieeqiksskeelfnlrfqlatgqleetarirtvrktiarlktva
rereieqskanq

    Sequence, based on observed residues (ATOM records):
    >6wqqK (K:)
kakeirnlttseieeqiksskeelfnlrfqlatgqleetarirtvrktiarlktvarere

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6wqqL (L:)
mtkgilgrkigmtqvfgengelipvtvveakenvvlqkktvevdgynaiqvgfedkkayk
kdaksnkyankpaeghakkadaapkrfirefrnvdvdayevgqevsvdtfvagdvidvtg
vskgkgfqgaikrhgqsrgpmshgshfhrapgsvgmasdasrvfkgqkmpgrmggntvtv
qnlevvqvdtenkvilvkgnvpgpkkglveirtsikk

    Sequence, based on observed residues (ATOM records):
    >6wqqL (L:)
tkgilgrkigmtqvfgengelipvtvveakenvvlqkktvevdgynaiqvgfedkkaykk
daksnkyankpaeghakkadaapkrfirefrnvdvdayevgqevsvdtfvagdvidvtgv
skgkgfqgaikrhgqsrgpmshgshfhrapgsvgmasdasrvfkgqkmpgrmggntvtvq
nlevvqvdtenkvilvkgnvpgpkkglveirtsik

  • Chain 'M':
    Sequence, based on SEQRES records:
    >6wqqM (M:)
aklqitltrsvigrpetqrktvealglkktnssvvvednpairgqinkvkhlvtveek

    Sequence, based on observed residues (ATOM records):
    >6wqqM (M:)
aklqitltrsvigrpetqrktvealglkktnssvvvednpairgqinkvkhlvtve

  • Chain 'N':
    Sequence, based on SEQRES records:
    >6wqqN (N:)
mavpkrrtsktrknkrrthfkisvpgmtecpncgeyklshrvckncgsyngeeaaak

    Sequence, based on observed residues (ATOM records):
    >6wqqN (N:)
avpkrrtsktrknkrrthfkisvpgmtecpncgeyklshrvckncgsyng

  • Chain 'O':
    Sequence, based on SEQRES records:
    >6wqqO (O:)
mrvnvtlactecgdrnyittknkrnnpervemkkfcsrenkqtlhretk

    Sequence, based on observed residues (ATOM records):
    >6wqqO (O:)
mrvnvtlactecgdrnyittknkrnnpervemkkfcsrenkqtlhre

  • Chain 'P':
    Sequence, based on SEQRES records:
    >6wqqP (P:)
mevfcmvkrtyqpnkrkhskvhgfrkrmstkngrkvlarrrrkgrkvlsa

    Sequence, based on observed residues (ATOM records):
    >6wqqP (P:)
vkrtyqpnkrkhskvhgfrkrmstkngrkvlarrrrkgrkvlsa

  • Chain 'Q':
    Sequence, based on SEQRES records:
    >6wqqQ (Q:)
mpkmkthrgaakrvkrtasgqlkrsraftshlfankstkqkrqlrkarlvsksdmkrvkq
llayk

    Sequence, based on observed residues (ATOM records):
    >6wqqQ (Q:)
pkmkthrgaakrvkrtasgqlkrsraftshlfankstkqkrqlrkarlvsksdmkrvkql
layk

  • Chain 'R':
    Sequence; same for both SEQRES and ATOM records:
    >6wqqR (R:)
mkvrpsvkpicekckvikrkgkvmvicenpkhkqrqg

  • Chain 'S':
    Sequence, based on SEQRES records:
    >6wqqS (S:)
manydvlkldgtksgsielsdavfgiepnnsvlfeainlqraslrqgthavknrsavsgg
grkpwkqkgtgrarqgtirapqwrgggivfgptprsyaykmpkkmrrlalrsalsfkvqe
ngltvvdafnfeapktkefknvlstleqpkkvlvvtenedvnvelsarnipgvqvttaqg
lnvlditnadslviteaaakkveevlg

    Sequence, based on observed residues (ATOM records):
    >6wqqS (S:)
sielsdavfgiepnnsvlfeainlqraslrqgthavknrsavsgggrkpwkqkgtgrarq
gtirapqwrgggivfgptprsyaykmpkkmrrlalrsalsfkvqengltvvdafnfeapk
tkefknvlstleqpkkvlvvtenedvnvelsarnipgvqvttaqglnvlditnadslvit
eaaakkveevlg

  • Chain 'V':
    Sequence, based on SEQRES records:
    >6wqqV (V:)
mrqtfmanesnierkwyvidaegqtlgrlssevasilrgknkvtytphvdtgdyvivina
skieftgnketdkvyyrhsnhpggiksitagelrrtnperliensikgmlpstrlgekqg
kklfvyggaehphaaqqpenyelrg

    Sequence, based on observed residues (ATOM records):
    >6wqqV (V:)
rqtfmanesnierkwyvidaegqtlgrlssevasilrgknkvtytphvdtgdyvivinas
kieftgnketdkvyyrhsnhpggiksitagelrrtnperliensikgmlpstrlgekqgk
klfvyggaehphaaqqpenyelr

  • Chain 'W':
    Sequence, based on SEQRES records:
    >6wqqW (W:)
miqqetrlkvadnsgarevltikvlggsgrktanigdvivctvknatpggvvkkgdvvka
vivrtksgvrrndgsyikfdenacviirddkgprgtrifgpvarelregnfmkivslape
vl

    Sequence, based on observed residues (ATOM records):
    >6wqqW (W:)
miqqetrlkvadnsgarevltikvlggsgrktanigdvivctvknatpggvvkkgdvvka
vivrtksgvrrndgsyikfdenacviirddkgprgtrifgpvarelregnfmkivslape
v

  • Chain 'X':
    Sequence, based on SEQRES records:
    >6wqqX (X:)
mklhelkpaegsrkernrvgrgvatgngktsgrghkgqkarsgggvrpgfeggqlplfrr
lpkrgftninrkeyaivnldqlnkfedgtevtpallvesgvvkneksgikilgngsldkk
ltvkahkfsasaaeaidakggahevi

    Sequence, based on observed residues (ATOM records):
    >6wqqX (X:)
klhelkpaegsrkernrvgrgvatgngktsgrghkgqkarsgggvrpgfeggqlplfrrl
pkrgftninrkeyaivnldqlnkfedgtevtpallvesgvvkneksgikilgngsldkkl
tvkahkfsasaaeaidakggahev

  • Chain 'Y':
    Sequence, based on SEQRES records:
    >6wqqY (Y:)
mllpkrvkyrrqhrpkttgrskggnyvtfgefglqatttswitsrqiesariamtrymkr
ggkvwikifphtpytkkplevrmgagkgavegwiavvkpgrilfevagvseevarealrl
ashklpvktkfvkreelggetnes

    Sequence, based on observed residues (ATOM records):
    >6wqqY (Y:)
mllpkrvkyrrqhrpkttgrskggnyvtfgefglqatttswitsrqiesariamtrymkr
ggkvwikifphtpytkkplevrmgagkgavegwiavvkpgrilfevagvseevarealrl
ashklpvktkfvkree

  • Chain 'Z':
    Sequence, based on SEQRES records:
    >6wqqZ (Z:)
mgyrklgrtsdqrkamlrdlatsliiseriettearakevrsvveklitlgkkgdlasrr
naaktlrnveilnedettqtalqklfgeiaeryterqggytrilkqgprrgdgaesviie
lv

    Sequence, based on observed residues (ATOM records):
    >6wqqZ (Z:)
gyrklgrtsdqrkamlrdlatsliiseriettearakevrsvveklitlgkkgdlasrrn
aaktlrnveilnedettqtalqklfgeiaeryterqggytrilkqgprrgdgaesviiel
v

  • Chain 'a':
    Sequence, based on SEQRES records:
    >6wqqa (a:)
miskidknkvrlkrharvrtnlsgtaekprlnvyrsnkhiyaqiiddnkgvtlaqasskd
sdiattatkvelatkvgeaiakkaadkgikeivfdrggylyhgrvkalaeaaresglef

    Sequence, based on observed residues (ATOM records):
    >6wqqa (a:)
kidknkvrlkrharvrtnlsgtaekprlnvyrsnkhiyaqiiddnkgvtlaqassktatk
velatkvgeaiakkaadkgikeivfdrggylyhgrvkalaeaaresglef