PDB entry 6wjy

View 6wjy on RCSB PDB site
Description: human ido1 in complex with compound 4-a
Class: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Keywords: INDOLEAMINE DIOXYGENASE, HEME, INHIBITOR, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE inhibitor complex
Deposited on 2020-04-14, released 2020-08-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-09-09, with a file datestamp of 2020-09-04.
Experiment type: XRAY
Resolution: 1.91 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Indoleamine 2,3-dioxygenase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: IDO1, IDO, INDO
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14902 (1-End)
      • initiating methionine (0)
    Domains in SCOPe 2.07: d6wjya_
  • Chain 'B':
    Compound: Indoleamine 2,3-dioxygenase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: IDO1, IDO, INDO
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6wjyb_
  • Heterogens: U41, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6wjyA (A:)
miskeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidh
ltdhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadc
vlanwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamq
mqerdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvy
egfwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcs
lesnpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqqpkenktse
dpskleakgtggtdlmnflktvrstteksllkeg

    Sequence, based on observed residues (ATOM records): (download) 
    >6wjyA (A:)
miskeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidh
ltdhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadc
vlanwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamq
mqerdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvy
egfwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcs
lesnpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqqpggtdlmn
flktvrstteksllk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6wjyB (B:)
miskeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidh
ltdhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadc
vlanwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamq
mqerdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvy
egfwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcs
lesnpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqqpkenktse
dpskleakgtggtdlmnflktvrstteksllkeg

    Sequence, based on observed residues (ATOM records): (download) 
    >6wjyB (B:)
iskeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhl
tdhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcv
lanwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqm
qerdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvye
gfwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsl
esnpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqqggtdlmnfl
ktvrstteksllkeg