PDB entry 6wia

View 6wia on RCSB PDB site
Description: crystal structure of human protective protein/cathepsin a, dfp-inhibited (aged)
Class: hydrolase
Keywords: Lysosomal, Cathepsin A, CatA, CTSA, organophosphate, renin-angiotensin system (RAS), HYDROLASE
Deposited on 2020-04-09, released 2020-04-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-04-29, with a file datestamp of 2020-04-24.
Experiment type: XRAY
Resolution: 2.21 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: lysosomal protective protein
    Species: Homo sapiens [TaxId:9606]
    Gene: CTSA, PPGB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6wiaa_
  • Heterogens: MIS, NAG, ACT, CD, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6wiaA (A:)
apdqdeiqrlpglakqpsfrqysgylkgsgskhlhywfvesqkdpenspvvlwlnggpgc
ssldglltehgpflvqpdgvtleynpyswnlianvlylespagvgfsysddkfyatndte
vaqsnfealqdffrlfpeyknnklfltgesyagiyiptlavlvmqdpsmnlqglavgngl
ssyeqndnslvyfayyhgllgnrlwsslqthccsqnkcnfydnkdlecvtnlqevarivg
nsglniynlyapcaggvpshfryekdtvvvqdlgniftrlplkrmwhqallrsgdkvrmd
ppctnttaastylnnpyvrkalnipeqlpqwdmcnflvnlqyrrlyrsmnsqylkllssq
kyqillyngdvdmacnfmgdewfvdslnqkmevqrrpwlvkygdsgeqiagfvkefshia
fltikgaghmvptdkplaaftmfsrflnkqpyhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6wiaA (A:)
apdqdeiqrlpglakqpsfrqysgylkgsgskhlhywfvesqkdpenspvvlwlnggpgc
ssldglltehgpflvqpdgvtleynpyswnlianvlylespagvgfsysddkfyatndte
vaqsnfealqdffrlfpeyknnklfltgesyagiyiptlavlvmqdpsmnlqglavgngl
ssyeqndnslvyfayyhgllgnrlwsslqthccsqnkcnfydnkdlecvtnlqevarivg
nsglniynlyapcaggvpsmdppctnttaastylnnpyvrkalnipeqlpqwdmcnflvn
lqyrrlyrsmnsqylkllssqkyqillyngdvdmacnfmgdewfvdslnqkmevqrrpwl
vkygdsgeqiagfvkefshiafltikgaghmvptdkplaaftmfsrflnkq