SCOPe 2.08: Structural Classification of Proteins

PDB entry 6whv

View 6whv on RCSB PDB site
Description: glun1b-glun2b nmda receptor in complex with sdz 220-040 and l689,560, class 2
Deposited on 2020-04-08, released 2020-08-05
The last revision was dated 2020-08-05, with a file datestamp of 2020-07-31.
Experiment type: EM
Resolution: 4.05 Å
R-factor: N/A
AEROSPACI score: 0.06 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Glutamate receptor ionotropic, NMDA 1
Species: Rattus norvegicus [TaxId:10116]
Gene: Grin1, Nmdar1
Database cross-references and differences (RAF-indexed):
- Uniprot P35439
  - conflict (60)
  - conflict (259)
  - conflict (370)
  - conflict (491)
  - conflict (511)
  - conflict (791)
  - conflict (830)
Chain 'B':
Compound: Glutamate receptor ionotropic, NMDA 2B
Species: Rattus norvegicus [TaxId:10116]
Gene: Grin2b
Database cross-references and differences (RAF-indexed):
- Uniprot Q00960
  - conflict (378)
  - conflict (587)
  - conflict (868)
Chain 'C':
Compound: Glutamate receptor ionotropic, NMDA 1
Species: Rattus norvegicus [TaxId:10116]
Gene: Grin1, Nmdar1
Database cross-references and differences (RAF-indexed):
- Uniprot P35439
  - conflict (60)
  - conflict (259)
  - conflict (370)
  - conflict (491)
  - conflict (511)
  - conflict (791)
  - conflict (830)
Chain 'D':
Compound: Glutamate receptor ionotropic, NMDA 2B
Species: Rattus norvegicus [TaxId:10116]
Gene: Grin2b
Database cross-references and differences (RAF-indexed):
- Uniprot Q00960
  - conflict (378)
  - conflict (587)
  - conflict (868)
Heterogens: QGM, QGP, NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

Chain 'A':
Sequence, based on SEQRES records:

>6whvA (A:)
mstmhlltfallfscsfaraasdpkivnigavlstrkheqmfreavnqankrhgswkiql
qatsvthkpnaiqmalsvcedlissqvyailvshpptpndhftptpvsytagfyripvlg
lttrmsiysdksihlsflrtvppyshqssvwfemmrvynwnhiillvsddhegraaqkrl
etlleereskskkrnyenldqlsydnkrgpkaekvlqfdpgtknvtallmearelearvi
ilsaseddaatvyraaamldmtgsgyvwlvgereisgnalryapdgiiglqlingknesa
hisdavgvvaqavhellekenitdpprgcvgntniwktgplfkrvlmsskyadgvtgrve
fnedgdrkfaqysimnlqnrklvqvgiyngthvipndrkiiwpggetekprgyqmstrlk
ivtihqepfvyvkptmsdgtckeeftvngdpvkkvictgpndtspgsprhtvpqccygfc
idlliklartmqftyevhlvadgkfgtqervqnsnkkewngmmgellsgqadmivaplti
nneraqyiefskpfkyqgltilvkkeiprstldsfmqpfqstlwllvglsvhvvavmlyl
ldrfspfgrfkvnsqsestdaltlssamwfswgvllnsgigegaprsfsarilgmvwagf
amiivasytanlaaflvldrpeeritgindprlrnpsdkfiyatvkqssvdiyfrrqvel
stmyrhmekhnyesaaeaiqavrdnklhafiwdsavlefeasqkcdlvttgelffrsgfg
igmrkdspwkqqvslsilkshengfmedldktwvryqecdsrsnapatltcenmagvfml
vaggivagiflifieiaykrhkdarrkqmqlafaavnvwrknlqdrksgraepdpkkkat
fraitstlassfkrrrsskdtstgggrgalqnqkdtvlprraiereegqlqlcsrhres

Sequence, based on observed residues (ATOM records):

>6whvA (A:)
kivnigavlstrkheqmfreavnqankriqlqatsvthkpnaiqmalsvcedlissqvya
ilvshpptpndhftptpvsytagfyripvlglttrmsiysdksihlsflrtvppyshqss
vwfemmrvynwnhiillvsddhegraaqkrletlleereskydnkrgpkaekvlqfdpgt
knvtallmearelearviilsaseddaatvyraaamldmtgsgyvwlvgereisgnalry
apdgiiglqlingknesahisdavgvvaqavhellekenitdpprgcvgntniwktgplf
krvlmsskyadgvtgrvefnedgdrkfaqysimnlqnrklvqvgiyngthvipndrkiiw
pggetekprgyqmstrlkivtihqepfvyvkptmsdgtckeeftvngdpvkkvictgpnd
tspgsprhtvpqccygfcidlliklartmqftyevhlvadgkfgtqervqnsnkkewngm
mgellsgqadmivapltinneraqyiefskpfkyqgltilvkkeiprstldsfmqpfqst
lwllvglsvhvvavmlylldrfstlssamwfswgvllnsgigegaprsfsarilgmvwag
famiivasytanlaaflvldrpeeritgindprlrnpsdkfiyatvkqssvdiyfrrqve
lstmyrhmekhnyesaaeaiqavrdnklhafiwdsavlefeasqkcdlvttgelffrsgf
gigmrkdspwkqqvslsilkshengfmedldktwvryqecdsrsnapatltcenmagvfm
lvaggivagiflifieiaykrhk

Chain 'B':
Sequence, based on SEQRES records:

>6whvB (B:)
mgtmrlfllavlflfsfaratgwshpqfekgggsgggsggsawshpqfekgalvprgrsq
ksppsigiavilvgtsdevaikdahekddfhhlsvvprvelvamnetdpksiitricdlm
sdrkiqgvvfaddtdqeaiaqildfisaqtltpilgihggssmimadkdessmffqfgps
ieqqasvmlnimeeydwyifsivttyfpgyqdfvnkirstiensfvgweleevllldmsl
ddgdskiqnqlkklqspiillyctkeeatyifevansvgltgygytwivpslvagdtdtv
psefptglisvsydewdyglparvrdgiaiittaasdmlsehsfipepksscynthekri
yqsnmlnrylinvtfegrdlsfsedgyqmhpklviillnkerkwervgkwkdkslqmkyy
vwprmcpeteeqeddhlsivtleeapfvivesvdplsgtcmrntvpcqkriisenktdee
pgyikkcckgfcidilkkisksvkftydlylvtngkhgkkingtwngmigevvmkrayma
vgsltineersevvdfsvpfietgisvmvsrsngtvspsaflepfsacvwvmmfvmlliv
savavfvfeyfspvgynrsladgrepggpsftigkaiwllwglvfnnsvpvqnpkgttsk
imvsvwaffaviflasytanlaafmiqeeyvdqvsglsdkkfqrpndfsppfrfgtvpng
sternirnnyaemhaymgkfnqrgvddallslktgkldafiydaavlnymagrdegcklv
tigsgkvfastgygiaiqkdsgwkrqvdlailqlfgdgemeelealwltgichneknevm
ssqldidnmagvfymlgaamalslitfisehlfywqfrhsfmg

Sequence, based on observed residues (ATOM records):

>6whvB (B:)
igiavilvgtsdevaikdahekddfhhlsvvprvelvamnetdpksiitricdlmsdrki
qgvvfaddtdqeaiaqildfisaqtltpilgihggssmimadkdessmffqfgpsieqqa
svmlnimeeydwyifsivttyfpgyqdfvnkirstiensfvgweleevllldmslddgds
kiqnqlkklqspiillyctkeeatyifevansvgltgygytwivpslvagdtdtvpsefp
tglisvsydewdyglparvrdgiaiittaasdmlsehsfipepksscynthekriyqsnm
lnrylinvtfegrdlsfsedgyqmhpklviillnkerkwervgkwkdkslqmkyyvwprm
dhlsivtleeapfvivesvdplsgtcmrntvpcqkriisenktdeepgyikkcckgfcid
ilkkisksvkftydlylvtngkhgkkingtwngmigevvmkraymavgsltineersevv
dfsvpfietgisvmvsrsngtvspsaflepfsacvwvmmfvmllivsavavfvfeysfti
gkaiwllwglvfnnsvpvqnpkgttskimvsvwaffaviflasytanlaafmiqeeyvdq
vsglsdkkfqrpndfsppfrfgtvpngsternirnnyaemhaymgkfnqrgvddallslk
tgkldafiydaavlnymagrdegcklvtigsgkvfastgygiaiqkdsgwkrqvdlailq
lfgdgemeelealwltgichneknevmssqldidnmagvfymlgaamalslitfisehlf
ywq

Chain 'C':
Sequence, based on SEQRES records:

>6whvC (C:)
mstmhlltfallfscsfaraasdpkivnigavlstrkheqmfreavnqankrhgswkiql
qatsvthkpnaiqmalsvcedlissqvyailvshpptpndhftptpvsytagfyripvlg
lttrmsiysdksihlsflrtvppyshqssvwfemmrvynwnhiillvsddhegraaqkrl
etlleereskskkrnyenldqlsydnkrgpkaekvlqfdpgtknvtallmearelearvi
ilsaseddaatvyraaamldmtgsgyvwlvgereisgnalryapdgiiglqlingknesa
hisdavgvvaqavhellekenitdpprgcvgntniwktgplfkrvlmsskyadgvtgrve
fnedgdrkfaqysimnlqnrklvqvgiyngthvipndrkiiwpggetekprgyqmstrlk
ivtihqepfvyvkptmsdgtckeeftvngdpvkkvictgpndtspgsprhtvpqccygfc
idlliklartmqftyevhlvadgkfgtqervqnsnkkewngmmgellsgqadmivaplti
nneraqyiefskpfkyqgltilvkkeiprstldsfmqpfqstlwllvglsvhvvavmlyl
ldrfspfgrfkvnsqsestdaltlssamwfswgvllnsgigegaprsfsarilgmvwagf
amiivasytanlaaflvldrpeeritgindprlrnpsdkfiyatvkqssvdiyfrrqvel
stmyrhmekhnyesaaeaiqavrdnklhafiwdsavlefeasqkcdlvttgelffrsgfg
igmrkdspwkqqvslsilkshengfmedldktwvryqecdsrsnapatltcenmagvfml
vaggivagiflifieiaykrhkdarrkqmqlafaavnvwrknlqdrksgraepdpkkkat
fraitstlassfkrrrsskdtstgggrgalqnqkdtvlprraiereegqlqlcsrhres

Sequence, based on observed residues (ATOM records):

>6whvC (C:)
kivnigavlstrkheqmfreavnqankriqlqatsvthkpnaiqmalsvcedlissqvya
ilvshpptpndhftptpvsytagfyripvlglttrmsiysdksihlsflrtvppyshqss
vwfemmrvynwnhiillvsddhegraaqkrletlleereskkrgpkaekvlqfdpgtknv
tallmearelearviilsaseddaatvyraaamldmtgsgyvwlvgereisgnalryapd
giiglqlingknesahisdavgvvaqavhellekenitdpprgcvgntniwktgplfkrv
lmsskyadgvtgrvefnedgdrkfaqysimnlqnrklvqvgiyngthvipndrkiiwpgg
etekprgyqmstrlkivtihqepfvyvkptmsdgtckeeftvngdpvkkvictgpndtsp
gsprhtvpqccygfcidlliklartmqftyevhlvadgkfgtqervqnsnkkewngmmge
llsgqadmivapltinneraqyiefskpfkyqgltilvkkeiprstldsfmqpfqstlwl
lvglsvhvvavmlylldrfstlssamwfswgvllnsgigegaprsfsarilgmvwagfam
iivasytanlaaflvldrpeeritgindprlrnpsdkfiyatvkqssvdiyfrrqvelst
myrhmekhnyesaaeaiqavrdnklhafiwdsavlefeasqkcdlvttgelffrsgfgig
mrkdspwkqqvslsilkshengfmedldktwvryqecdsrsnapatltcenmagvfmlva
ggivagiflifieiaykrhk

Chain 'D':
Sequence, based on SEQRES records:

>6whvD (D:)
mgtmrlfllavlflfsfaratgwshpqfekgggsgggsggsawshpqfekgalvprgrsq
ksppsigiavilvgtsdevaikdahekddfhhlsvvprvelvamnetdpksiitricdlm
sdrkiqgvvfaddtdqeaiaqildfisaqtltpilgihggssmimadkdessmffqfgps
ieqqasvmlnimeeydwyifsivttyfpgyqdfvnkirstiensfvgweleevllldmsl
ddgdskiqnqlkklqspiillyctkeeatyifevansvgltgygytwivpslvagdtdtv
psefptglisvsydewdyglparvrdgiaiittaasdmlsehsfipepksscynthekri
yqsnmlnrylinvtfegrdlsfsedgyqmhpklviillnkerkwervgkwkdkslqmkyy
vwprmcpeteeqeddhlsivtleeapfvivesvdplsgtcmrntvpcqkriisenktdee
pgyikkcckgfcidilkkisksvkftydlylvtngkhgkkingtwngmigevvmkrayma
vgsltineersevvdfsvpfietgisvmvsrsngtvspsaflepfsacvwvmmfvmlliv
savavfvfeyfspvgynrsladgrepggpsftigkaiwllwglvfnnsvpvqnpkgttsk
imvsvwaffaviflasytanlaafmiqeeyvdqvsglsdkkfqrpndfsppfrfgtvpng
sternirnnyaemhaymgkfnqrgvddallslktgkldafiydaavlnymagrdegcklv
tigsgkvfastgygiaiqkdsgwkrqvdlailqlfgdgemeelealwltgichneknevm
ssqldidnmagvfymlgaamalslitfisehlfywqfrhsfmg

Sequence, based on observed residues (ATOM records):

>6whvD (D:)
sigiavilvgtsdevaikdahekddfhhlsvvprvelvamnetdpksiitricdlmsdrk
iqgvvfaddtdqeaiaqildfisaqtltpilgihggssmimadkdessmffqfgpsieqq
asvmlnimeeydwyifsivttyfpgyqdfvnkirstiensfvgweleevllldmslddgd
skiqnqlkklqspiillyctkeeatyifevansvgltgygytwivpslvagdtdtvpsef
ptglisvsydewdyglparvrdgiaiittaasdmlsehsfipepksscynthekriyqsn
mlnrylinvtfegrdlsfsedgyqmhpklviillnkerkwervgkwkdkslqmkyyvwpr
mddhlsivtleeapfvivesvdplsgtcmrntvpcqkriisendeepgyikkcckgfcid
ilkkisksvkftydlylvtngkhgkkingtwngmigevvmkraymavgsltineersevv
dfsvpfietgisvmvsrsngtvspsaflepfsacvwvmmfvmllivsavavfvfeypsft
igkaiwllwglvfnnsvpvqnpkgttskimvsvwaffaviflasytanlaafmiqeeyvd
qvsglsdkkfqrpndfsppfrfgtvpngsternirnnyaemhaymgkfnqrgvddallsl
ktgkldafiydaavlnymagrdegcklvtigsgkvfastgygiaiqkdsgwkrqvdlail
qlfgdgemeelealwltgichneknevmssqldidnmagvfymlgaamalslitfisehl
fywq