PDB entry 6wfg

View 6wfg on RCSB PDB site
Description: Crystal structure of human Naa50 in complex with an inhibitor (compound 3) identified using DNA encoded library technology
Class: transferase/inhibitor
Keywords: N-alpha-acetyltransferase 50, Inhibitor complex, DNA encoded library, CoA, TRANSFERASE, TRANSFERASE-INHIBITOR complex
Deposited on 2020-04-03, released 2020-07-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-01, with a file datestamp of 2020-06-26.
Experiment type: XRAY
Resolution: 2.16 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: N-alpha-acetyltransferase 50
    Species: Homo sapiens [TaxId:9606]
    Gene: NAA50, MAK3, NAT13, NAT5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6wfga_
  • Chain 'C':
    Compound: N-alpha-acetyltransferase 50
    Species: Homo sapiens [TaxId:9606]
    Gene: NAA50, MAK3, NAT13, NAT5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6wfgc_
  • Chain 'E':
    Compound: N-alpha-acetyltransferase 50
    Species: Homo sapiens [TaxId:9606]
    Gene: NAA50, MAK3, NAT13, NAT5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6wfge_
  • Heterogens: U3V, COA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6wfgA (A:)
gsmkgsrielgdvtphnikqlkrlnqvifpvsyndkfykdvlevgelaklayfndiavga
vccrvdhsqnqkrlyimtlgclapyrrlgigtkmlnhvlnicekdgtfdniylhvqisne
saidfyrkfgfeiietkknyykriepadahvlqknlkvpsgqnadvqktdn

    Sequence, based on observed residues (ATOM records): (download) 
    >6wfgA (A:)
rielgdvtphnikqlkrlnqvifpvsyndkfykdvlevgelaklayfndiavgavccrvd
hsqnqkrlyimtlgclapyrrlgigtkmlnhvlnicekdgtfdniylhvqisnesaidfy
rkfgfeiietkknyykriepadahvlqknl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6wfgC (C:)
gsmkgsrielgdvtphnikqlkrlnqvifpvsyndkfykdvlevgelaklayfndiavga
vccrvdhsqnqkrlyimtlgclapyrrlgigtkmlnhvlnicekdgtfdniylhvqisne
saidfyrkfgfeiietkknyykriepadahvlqknlkvpsgqnadvqktdn

    Sequence, based on observed residues (ATOM records): (download) 
    >6wfgC (C:)
gsrielgdvtphnikqlkrlnqvifpvsyndkfykdvlevgelaklayfndiavgavccr
vdhsqnqkrlyimtlgclapyrrlgigtkmlnhvlnicekdgtfdniylhvqisnesaid
fyrkfgfeiietkknyykriepadahvlqknl

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6wfgE (E:)
gsmkgsrielgdvtphnikqlkrlnqvifpvsyndkfykdvlevgelaklayfndiavga
vccrvdhsqnqkrlyimtlgclapyrrlgigtkmlnhvlnicekdgtfdniylhvqisne
saidfyrkfgfeiietkknyykriepadahvlqknlkvpsgqnadvqktdn

    Sequence, based on observed residues (ATOM records): (download) 
    >6wfgE (E:)
srielgdvtphnikqlkrlnqvifpvsyndkfykdvlevgelaklayfndiavgavccrv
dhsqnqkrlyimtlgclapyrrlgigtkmlnhvlnicekdgtfdniylhvqisnesaidf
yrkfgfeiietkknyykriepadahvlqknl