PDB entry 6wax

View 6wax on RCSB PDB site
Description: C-terminal SH2 domain of p120RasGAP
Class: signaling protein
Keywords: SH2 domain, RasGAP, phosphopeptide, phosphotyrosine, SIGNALING PROTEIN
Deposited on 2020-03-26, released 2020-06-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-06-17, with a file datestamp of 2020-06-12.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ras GTPase-activating protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: RASA1, GAP, RASA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20936 (2-106)
      • engineered mutation (34)
      • engineered mutation (64)
    Domains in SCOPe 2.07: d6waxa_
  • Chain 'B':
    Compound: Ras GTPase-activating protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: RASA1, GAP, RASA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20936 (Start-106)
      • engineered mutation (34)
      • engineered mutation (64)
    Domains in SCOPe 2.07: d6waxb_
  • Heterogens: SO4, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6waxA (A:)
    gsgreedphegkiwfhgkiskqeaynllmtvgqvssflvrpsdntpgdyslyfrtneniq
    rfkisptpnnqfmmggryynsigdiidhyrkeqivegyylkepvpmq
    

    Sequence, based on observed residues (ATOM records): (download)
    >6waxA (A:)
    greedphegkiwfhgkiskqeaynllmtvgqvssflvrpsdntpgdyslyfrtneniqrf
    kisptpnnqfmmggryynsigdiidhyrkeqivegyylkepvpmq
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6waxB (B:)
    gsgreedphegkiwfhgkiskqeaynllmtvgqvssflvrpsdntpgdyslyfrtneniq
    rfkisptpnnqfmmggryynsigdiidhyrkeqivegyylkepvpmq
    

    Sequence, based on observed residues (ATOM records): (download)
    >6waxB (B:)
    edphegkiwfhgkiskqeaynllmtvgqvssflvrpsdntpgdyslyfrtneniqrfkis
    ptpnnqfmmggryynsigdiidhyrkeqivegyylkepvpmq