PDB entry 6w8v

View 6w8v on RCSB PDB site
Description: crystal structure of mouse dnmt1 in complex with acg dna
Deposited on 2020-03-21, released 2020-07-08
The last revision was dated 2020-07-08, with a file datestamp of 2020-07-03.
Experiment type: XRAY
Resolution: 3.12 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA (cytosine-5)-methyltransferase 1
    Species: Mus musculus [TaxId:10090]
    Gene: Dnmt1, Dnmt, Met1, Uim
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: DNA (cytosine-5)-methyltransferase 1
    Species: Mus musculus [TaxId:10090]
    Gene: Dnmt1, Dnmt, Met1, Uim
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: acg DNA (5'-d(*cp*cp*tp*tp*cp*(5cm)p*gp*tp*ap*ap*gp*t)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'D':
    Compound: acg DNA (5'-d(*ap*cp*tp*tp*ap*(c49)p*gp*gp*ap*ap*gp*g)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'E':
    Compound: acg DNA (5'-d(*cp*cp*tp*tp*cp*(5cm)p*gp*tp*ap*ap*gp*t)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'F':
    Compound: acg DNA (5'-d(*ap*cp*tp*tp*ap*(c49)p*gp*gp*ap*ap*gp*g)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Heterogens: 5CM, C49, SAH, ZN

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6w8vA (A:)
skdriswlgqpmkieenrtyyqkvsideemlevgdcvsvipddsskplylarvtalwedk
ngqmmfhahwfcagtdtvlgatsdplelflvgecenmqlsyihskvkviykapsenwame
ggtdpettlpgaedgktyffqlwynqeyarfesppktqptednkhkfclscirlaelrqk
empkvleqieevdgrvycssitkngvvyrlgdsvylppeaftfnikvaspvkrpkkdpvn
etlypehyrkysdyikgsnldapepyrigrikeihcgkkkgkvneadiklrlykfyrpen
thrsyngsyhtdinmlywsdeeavvnfsdvqgrctveygedllesiqdysqggpdrfyfl
eaynsktknfedppnharspgnkgkgkgkgkgkgkhqvsepkepeaaiklpklrtldvfs
gcgglsegfhqagisetlwaiemwdpaaqafrlnnpgttvftedcnvllklvmagevtns
lgqrlpqkgdvemlcggppcqgfsgmnrfnsrtyskfknslvvsflsycdyyrprfflle
nvrnfvsyrrsmvlkltlrclvrmgyqctfgvlqagqygvaqtrrraiilaaapgeklpl
fpeplhvfapracqlsvvvddkkfvsnitrlssgpfrtitvrdtmsdlpeiqngasnsei
pyngeplswfqrqlrgshyqpilrdhickdmsplvaarmrhiplfpgsdwrdlpniqvrl
gdgviahklqytfhdvkngysstgalrgvcscaegkacdpesrqfstlipwclphtgnrh
nhwaglygrlewdgffsttvtnpepmgkqgrvlhpeqhrvvsvrecarsqgfpdsyrffg
nildrhrqvgnavppplakaigleiklcllssa

    Sequence, based on observed residues (ATOM records):
    >6w8vA (A:)
driswlgqpmkieenrtyyqkvsideemlevgdcvsvipddsskplylarvtalwedkng
qmmfhahwfcagtdtvlgatsdplelflvgecenmqlsyihskvkviykapsenwamegg
edgktyffqlwynqeyarfesppktqptednkhkfclscirlaelrqkempkvleqieev
dgrvycssitkngvvyrlgdsvylppeaftfnikvaspvkrpkkdpvnetlypehyrkys
dyikgsnldapepyrigrikeihcgkkkgkvneadiklrlykfyrpenthrsyngsyhtd
inmlywsdeeavvnfsdvqgrctveygedllesiqdysqggpdrfyfleaynsktknfed
ppnharspgnklpklrtldvfsgcgglsegfhqagisetlwaiemwdpaaqafrlnnpgt
tvftedcnvllklvmagevtnslgqrlpqkgdvemlcggppcqgfsgmnrfnsyskfkns
lvvsflsycdyyrprffllenvrnfvsyrrsmvlkltlrclvrmgyqctfgvlqagqygv
aqtrrraiilaaapgeklplfpeplhvfapracqlsvvvddkkfvsnitrlssgpfrtit
vrdtmsdlpeiqngasnseipyngeplswfqrqlrgshyqpilrdhickdmsplvaarmr
hiplfpgsdwrdlpniqvrlgdgviahklqytfhdvkngysstgalrgvcscaegkacdp
esrqfstlipwclphtgnrhnhwaglygrlewdgffsttvtnpepmgkqgrvlhpeqhrv
vsvrecarsqgfpdsyrffgnildrhrqvgnavppplakaigleiklclls

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6w8vB (B:)
skdriswlgqpmkieenrtyyqkvsideemlevgdcvsvipddsskplylarvtalwedk
ngqmmfhahwfcagtdtvlgatsdplelflvgecenmqlsyihskvkviykapsenwame
ggtdpettlpgaedgktyffqlwynqeyarfesppktqptednkhkfclscirlaelrqk
empkvleqieevdgrvycssitkngvvyrlgdsvylppeaftfnikvaspvkrpkkdpvn
etlypehyrkysdyikgsnldapepyrigrikeihcgkkkgkvneadiklrlykfyrpen
thrsyngsyhtdinmlywsdeeavvnfsdvqgrctveygedllesiqdysqggpdrfyfl
eaynsktknfedppnharspgnkgkgkgkgkgkgkhqvsepkepeaaiklpklrtldvfs
gcgglsegfhqagisetlwaiemwdpaaqafrlnnpgttvftedcnvllklvmagevtns
lgqrlpqkgdvemlcggppcqgfsgmnrfnsrtyskfknslvvsflsycdyyrprfflle
nvrnfvsyrrsmvlkltlrclvrmgyqctfgvlqagqygvaqtrrraiilaaapgeklpl
fpeplhvfapracqlsvvvddkkfvsnitrlssgpfrtitvrdtmsdlpeiqngasnsei
pyngeplswfqrqlrgshyqpilrdhickdmsplvaarmrhiplfpgsdwrdlpniqvrl
gdgviahklqytfhdvkngysstgalrgvcscaegkacdpesrqfstlipwclphtgnrh
nhwaglygrlewdgffsttvtnpepmgkqgrvlhpeqhrvvsvrecarsqgfpdsyrffg
nildrhrqvgnavppplakaigleiklcllssa

    Sequence, based on observed residues (ATOM records):
    >6w8vB (B:)
driswlgqpmkieenrtyyqkvsideemlevgdcvsvipddsskplylarvtalwedkng
qmmfhahwfcagtdtvlgatsdplelflvgecenmqlsyihskvkviykapsenwamegg
tyffqlwynqeyarfesppktqptednkhkfclscirlaelrqkempkvleqieevdgrv
ycssitkngvvyrlgdsvylppeaftfnikvaspvkrpkkdpvnetlypehyrkysdyik
gsnldapepyrigrikeihcgkkkgkvneadiklrlykfyrpenthrsyngsyhtdinml
ywsdeeavvnfsdvqgrctveygedllesiqdysqggpdrfyfleaynsktknfedppnh
arspgnklpklrtldvfsgcgglsegfhqagisetlwaiemwdpaaqafrlnnpgttvft
edcnvllklvmagevtnslgqrlpqkgdvemlcggppcqgfsgmnrfnskfknslvvsfl
sycdyyrprffllenvrnfvsyrrsmvlkltlrclvrmgyqctfgvlqagqygvaqtrrr
aiilaaapgeklplfpeplhvfapracqlsvvvddkkfvsnitrlssgpfrtitvrdtms
dlpeiqngasnseipyngeplswfqrqlrgshyqpilrdhickdmsplvaarmrhiplfp
gsdwrdlpniqvrlgdgviahklqytfhdvkngysstgalrgvcscaegkacdpesrqfs
tlipwclphtgnrhnhwaglygrlewdgffsttvtnpepmgkqgrvlhpeqhrvvsvrec
arsqgfpdsyrffgnildrhrqvgnavppplakaigleiklclls

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.