PDB entry 6w74

View 6w74 on RCSB PDB site
Description: Structure of cIAP with compound 15
Class: ligase
Keywords: cIAP E3 PROTAC, LIGASE
Deposited on 2020-03-18, released 2020-11-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-11-18, with a file datestamp of 2020-11-13.
Experiment type: XRAY
Resolution: 2.11 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Baculoviral IAP repeat-containing protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: BIRC2, API1, MIHB, RNF48
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6w74a_
  • Heterogens: TKY, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6w74A (A:)
gsgpgssisnlsmqthaarmrtfmywpssvpvqpeqlasagfyyvgrnddvkcfccdggl
rcwesgddpwvehakwfprceflirmkgqefvdeiqgry

    Sequence, based on observed residues (ATOM records): (download) 
    >6w74A (A:)
mqthaarmrtfmywpssvpvqpeqlasagfyyvgrnddvkcfccdgglrcwesgddpwve
hakwfprceflirmkgqefvdeiqgry