PDB entry 6w5x

View 6w5x on RCSB PDB site
Description: crystal structure of human polymerase eta complexed with n7- benzylguanine and dctp*
Deposited on 2020-03-14, released 2021-03-17
The last revision was dated 2021-03-17, with a file datestamp of 2021-03-12.
Experiment type: XRAY
Resolution: 2.59 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA Polymerase ETA
    Species: Homo sapiens [TaxId:9606]
    Gene: POLH, RAD30, RAD30A, XPV
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: DNA (5'-d(*ap*gp*tp*gp*tp*gp*ap*g)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'T':
    Compound: DNA (5'-d(*cp*ap*tp*(drg)p*cp*tp*cp*ap*cp*ap*cp*t)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Heterogens: 7BG, 0KX, GOL, MN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6w5xA (A:)
matgqdrvvalvdmdcffvqveqrqnphlrnkpcavvqykswkgggiiavsyearafgvt
rsmwaddakklcpdlllaqvresrgkanltkyreasvevmeimsrfavierasideayvd
ltsavqerlqklqgqpisadllpstyieglpqgpttaeetvqkegmrkqglfqwldslqi
dnltspdlqltvgaviveemraaieretgfqcsagishnkvlaklacglnkpnrqtlvsh
gsvpqlfsqmpirkirslggklgasvieilgieymgeltqftesqlqshfgekngswlya
mcrgiehdpvkprqlpktigcsknfpgktalatreqvqwwllqlaqeleerltkdrndnd
rvatqlvvsirvqgdkrlsslrrccaltrydahkmshdaftvikncntsgiqtewspplt
mlflcatkfsas

    Sequence, based on observed residues (ATOM records):
    >6w5xA (A:)
matgqdrvvalvdmdcffvqveqrqnphlrnkpcavvqykswkgggiiavsyearafgvt
rsmwaddakklcpdlllaqvresrgkanltkyreasvevmeimsrfavierasideayvd
ltsavqerlqklqgqpisadllpstyieglpqgptvqkegmrkqglfqwldslqidnlts
pdlqltvgaviveemraaieretgfqcsagishnkvlaklacglnkpnrqtlvshgsvpq
lfsqmpirkirslggklgasvieilgieymgeltqftesqlqshfgekngswlyamcrgi
ehdpvkprqlpktigcsknfpgktalatreqvqwwllqlaqeleerltkdrndndrvatq
lvvsirvqgdkrlsslrrccaltrydahkmshdaftvikncntsgiqtewsppltmlflc
atkfsas

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.