PDB entry 6w44

View 6w44 on RCSB PDB site
Description: Crystal structure of HAO1 in complex with indazole acid inhibitor - compound 4
Class: oxidoreductase
Keywords: Inhibitor, Complex, OXIDOREDUCTASE
Deposited on 2020-03-10, released 2021-05-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-06-09, with a file datestamp of 2021-06-04.
Experiment type: XRAY
Resolution: 1.64 Å
R-factor: N/A
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hydroxyacid oxidase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: HAO1, GOX1, HAOX1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6w44a_
  • Heterogens: SLJ, FMN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6w44A (A:)
mlprlicindyeqhaksvlpksiydyyrsgandeetladniaafsrwklyprmlrnvaet
dlstsvlgqrvsmpicvgatamqrmahvdgelatvracqslgtgmmlsswatssieevae
agpealrwlqlyiykdrevtkklvrqaekmgykaifvtvdtpylgnrlddvrnrfklppq
lrmknfetstlsfspeenfgddsglaayvakaidpsiswedikwlrrltslpivakgilr
gddareavkhglngilvsnhgarqldgvpatidvlpeiveavegkvevfldggvrkgtdv
lkalalgakavfvgrpivwglafqgekgvqdvleilkeefrlamalsgcqnvkvidktlv
rknplavs

    Sequence, based on observed residues (ATOM records): (download) 
    >6w44A (A:)
prlicindyeqhaksvlpksiydyyrsgandeetladniaafsrwklyprmlrnvaetdl
stsvlgqrvsmpicvgatamqrmahvdgelatvracqslgtgmmlsswatssieevaeag
pealrwlqlyiykdrevtkklvrqaekmgykaifvtvdtpylgnrlddvrnglaayvaka
idpsiswedikwlrrltslpivakgilrgddareavkhglngilvsnhgarqldgvpati
dvlpeiveavegkvevfldggvrkgtdvlkalalgakavfvgrpivwglafqgekgvqdv
leilkeefrlamalsgcqnvkvidktlvrk