PDB entry 6w42

View 6w42 on RCSB PDB site
Description: HIV Integrase core domain in complex with inhibitor 2-(5-methyl-2-(2-(thiophen-2-yl)ethynyl)-1-benzofuran-3-yl)acetic acid
Class: transferase/transferase inhibitor
Keywords: Inhibitor, HIV Integrase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2020-03-09, released 2021-03-10
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-03-10, with a file datestamp of 2021-03-05.
Experiment type: XRAY
Resolution: 2.26 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HIV Integrase catalytic domain
    Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • PDB 6W42
    Domains in SCOPe 2.07: d6w42a_
  • Heterogens: SJY, SO4, IOD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6w42A (A:)
gsmhgevdcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagr
wpvktvhtdngsnftsttvkaacewagikqefgipynpqsqgvieasnkelkkiigqvrd
qaehlktavqmavfihnkkrkggiggysagerivdiiatdietke

    Sequence, based on observed residues (ATOM records): (download) 
    >6w42A (A:)
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftsttvkaacewagikqefgiasnkelkkiigqvrdqaehlktavqmavfihnkkr
kggiggysagerivdiiat